Phase 2 Hepatitis B Clinical Trials
41 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 41 trials
Recruiting
Phase 1Phase 2
TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Michael Hoelscher81 enrolled6 locationsNCT06513286
Recruiting
Phase 2
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Phase 2
Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region
Hepatitis B, Chronic
AusperBio Therapeutics Inc.84 enrolled8 locationsNCT07370207
Recruiting
Phase 2
VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B
Chronic Hepatitis B
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)50 enrolled1 locationNCT06092333
Recruiting
Phase 2
A Multicenter Study of AHB-137 Injection Combined With Other Hepatitis B Drugs
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.200 enrolled1 locationNCT07069569
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.60 enrolled1 locationNCT07137910
Recruiting
Phase 2
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Chronic Hepatitis B Infection
Aligos Therapeutics200 enrolled58 locationsNCT06963710
Recruiting
Phase 2
A Study of Hydronidone Capsules in Patients With Chronic Hepatitis B Virus-Related Liver Fibrosis
Chronic Hepatitis B-related Liver Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.150 enrolled1 locationNCT07417553
Recruiting
Phase 2
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B
Gilead Sciences150 enrolled62 locationsNCT02932150
Recruiting
Phase 2
A Study to Evaluate the Safety of Hydronidone Capsules in Patients With Liver Fibrosis
Chronic Hepatitis B With Hepatic Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.200 enrolled1 locationNCT07364448
Recruiting
Phase 1Phase 2
Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.76 enrolled1 locationNCT07413549
Recruiting
Phase 2
A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.30 enrolled1 locationNCT06993480
Recruiting
Phase 2
A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B
Chronic Hepatitis B
Fujian Shengdi Pharmaceutical Co., Ltd.369 enrolled1 locationNCT06425341
Recruiting
Phase 2
Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B
Chronic Hepatitis B
University of Maryland, Baltimore10 enrolled1 locationNCT06154278
Recruiting
Phase 2
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (A)
Anti-PD-1 AntibodyChronic Hepatitis B
The Second Affiliated Hospital of Chongqing Medical University120 enrolled1 locationNCT05769816
Recruiting
Phase 2
A Novel Combination Therapeutic Strategy Aiming to Functional Cure for Chronic Hepatitis B Virus Infection (Sustained HBsAg Loss) (B)
Anti-PD-1 AntibodyChronic Hepatitis BPeg-IFNα
The Second Affiliated Hospital of Chongqing Medical University120 enrolled1 locationNCT05771402
Recruiting
Phase 2Phase 3
A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series
DiphtheriaPoliomyelitisHepatitis B+3 more
LG Chem1,186 enrolled1 locationNCT06947499
Recruiting
Phase 2
Vaccinal Effect of HBsAg Monoclonal Ab VIR-3434 in Chronic Hepatitis B Infection [VISION]
Hepatitis B, Chronic
University Health Network, Toronto15 enrolled1 locationNCT06216470
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of Combination Therapy of BRII-179, BRII-835 and PEG-IFNα in Participants With Chronic Hepatitis B Virus (HBV) Infection (ENHANCE)
Chronic Hepatitis B Virus (HBV) Infection
Brii Biosciences Limited250 enrolled14 locationsNCT06650852
Recruiting
Phase 2
Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants (B-Sure)
Hepatitis B
GlaxoSmithKline450 enrolled51 locationsNCT04954859