Phase 1 Hepatitis Clinical Trials
69 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 69 trials
Recruiting
Phase 1Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Chronic Hepatitis Delta
Gilead Sciences107 enrolled15 locationsNCT07096193
Recruiting
Phase 1
hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis
Hepatitis B
Sclnow Biotechnology Co., Ltd.20 enrolled1 locationNCT03826433
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)
Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
Regeneron Pharmaceuticals132 enrolled3 locationsNCT06836609
Recruiting
Phase 1Phase 2
Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV
Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)30 enrolled10 locationsNCT07040319
Recruiting
Phase 1
A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B Virus (Hbv)
Jiyan Liu9 enrolled1 locationNCT07051187
Recruiting
Phase 1Phase 2
Study of TGM-312-SC01 in Healthy Participants and Adults With MASH
Healthy ParticipantsMASH - Metabolic Dysfunction-Associated Steatohepatitis
Tangram Therapeutics Plc99 enrolled1 locationNCT07427680
Recruiting
Phase 1
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
Hepatitis B Virus Infection
GigaGen, Inc.48 enrolled16 locationsNCT07024641
Recruiting
Phase 1
A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B
Chronic Hepatitis B Virus Infection
IntegerBio90 enrolled1 locationNCT07389044
Recruiting
Phase 1
Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function
Chronic Hepatitis B Infection
Aligos Therapeutics30 enrolled2 locationsNCT07342881
Recruiting
Phase 1Phase 2
Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.76 enrolled1 locationNCT07413549
Recruiting
Phase 1
Evaluation of Miricorilant on Liver Fat in Patients With MASLD
Nonalcoholic Steatohepatitis (NASH)
Corcept Therapeutics8 enrolled1 locationNCT06947304
Recruiting
Phase 1
ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult Participants
Metabolic Dysfunction-Associated Steatohepatitis
Eccogene72 enrolled1 locationNCT07334080
Recruiting
Phase 1
SA1211 Injection Phase 1 Study
Chronic Hepatitis B
Suzhou Siran Biotechnology Co.,Ltd.80 enrolled1 locationNCT07275918
Recruiting
Phase 1
A Study of SIPLIZUMAB in AILD and LT Patients
Autoimmune HepatitisPrimary Sclerosing CholangitisLiver Transplant Disorder+1 more
Elizabeth C. Verna8 enrolled1 locationNCT06455280
Recruiting
Phase 1
TLR-9 Adjuvanted Vaccination for Chronic Hepatitis B
Hepatitis BChronic Hepatitis B
University of Maryland, Baltimore10 enrolled1 locationNCT04843852
Recruiting
Phase 1
A Study to Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease
Hepatitis B
GlaxoSmithKline32 enrolled1 locationNCT07168356
Recruiting
Phase 1
A Study of SN2001 Dose, Safety & Immunogenicity in Healthy Adults
Chronic Hepatitis B Infection
Chimivac INC36 enrolled1 locationNCT07059403
Recruiting
Phase 1
A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Universitätsklinikum Hamburg-Eppendorf24 enrolled2 locationsNCT05727267
Not Yet Recruiting
Phase 1
A study to evaluate the safety, tolerability, pharmacokinetics and antiviral activity of BJT-678 in subjects with chronic Hepatitis B Infection, including subjects with Chronic Hepatitis D infection
Chronic Hepatitis D InfectionChronic Hepatitis B Infection
Bluejay Therapeutics, Inc50 enrolled3 locationsACTRN12625000281493
Recruiting
Phase 1
To Evaluate the Safety, Tolerability, Pharmacokinetics and Food Effects of IMM-H014 in Healthy Subjects
Nonalcoholic Steatohepatitis (NASH)
Changchun Intellicrown Pharmaceutical Co. LTD138 enrolled1 locationNCT06216041