Phase 1 Hepatitis Clinical Trials
81 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 81 trials
Recruiting
Phase 1Phase 2
TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Michael Hoelscher81 enrolled6 locationsNCT06513286
Recruiting
Phase 1Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Chronic Hepatitis Delta
Gilead Sciences200 enrolled19 locationsNCT07096193
Recruiting
Phase 1Phase 2
Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV
Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)30 enrolled10 locationsNCT07040319
Recruiting
Phase 1
A Phase I Clinical Study of AHB - 171 in Healthy Participants(HP) and Chronic Hepatitis B (CHB) Participants
Chronic Hepatitis B Infection
Ausper Biopharma Co., Ltd.110 enrolled1 locationNCT07511218
Recruiting
Phase 1
Safety and Antiviral Activity of a Monoclonal Hepatitis B Antibody: a Phase 1b, Open-label Trial in Individuals With Chronic Hepatitis D Infection
Hepatitis D, ChronicHepatitis B Chronic Infection
Aarhus University Hospital15 enrolled2 locationsNCT07610772
Recruiting
Phase 1
Evaluating the Pharmacokinetics and Safety of Miricorilant
Nonalcoholic Steatohepatitis (NASH)Non-alcoholic Fatty Liver Disease NAFLDMetabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis+1 more
Corcept Therapeutics15 enrolled1 locationNCT07553663
Recruiting
Phase 1
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection
Hepatitis B Virus Infection
GigaGen, Inc.48 enrolled17 locationsNCT07024641
Recruiting
Phase 1Phase 2
Study of TGM-312-SC01 in Healthy Participants and Adults With MASH
Healthy ParticipantsMASH - Metabolic Dysfunction-Associated Steatohepatitis
Tangram Therapeutics Plc99 enrolled1 locationNCT07427680
Recruiting
Phase 1
A Safety, Tolerability, Pharmacokinetics/Pharmacodynamics Study of HEC169584 Capsules in Healthy Subjects
Non Alcoholic Steatohepatitis
Sunshine Lake Pharma Co., Ltd.96 enrolled1 locationNCT07099118
Recruiting
Phase 1
hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis
Hepatitis B
Sclnow Biotechnology Co., Ltd.20 enrolled1 locationNCT03826433
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)
Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
Regeneron Pharmaceuticals132 enrolled3 locationsNCT06836609
Recruiting
Phase 1
A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B Virus (Hbv)
Jiyan Liu9 enrolled1 locationNCT07051187
Recruiting
Phase 1
A Study on IB-001 Dose Response and Tolerability in Healthy Adults and Those With Chronic Hepatitis B
Chronic Hepatitis B Virus Infection
IntegerBio90 enrolled1 locationNCT07389044
Recruiting
Phase 1
Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function
Chronic Hepatitis B Infection
Aligos Therapeutics30 enrolled2 locationsNCT07342881
Recruiting
Phase 1Phase 2
Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.76 enrolled1 locationNCT07413549
Recruiting
Phase 1
Evaluation of Miricorilant on Liver Fat in Patients With MASLD
Nonalcoholic Steatohepatitis (NASH)Metabolic dysfunction-associated steatohepatitis (MASH)Non-alcoholic Fatty Liver Disease NAFLD+1 more
Corcept Therapeutics8 enrolled1 locationNCT06947304
Recruiting
Phase 1
HepB mAb19 in Individuals With Chronic Hepatitis B Infection
Hepatitis BHepatitis B Virus
Rockefeller University37 enrolled2 locationsNCT05856890
Recruiting
Phase 1
ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult Participants
Metabolic Dysfunction-Associated Steatohepatitis
Eccogene72 enrolled1 locationNCT07334080
Recruiting
Phase 1
Phase 1b, Open-label Study of Tune-401 to Assess Safety, PK and PD in Adults With Chronic Hepatitis B
Chronic Hepatitis BHBVChronic Hep B+1 more
Tune Therapeutics, Inc.36 enrolled3 locationsNCT06671093
Recruiting
Phase 1
SA1211 Injection Phase 1 Study
Chronic Hepatitis B
Suzhou Siran Biotechnology Co.,Ltd.80 enrolled1 locationNCT07275918