Phase 2 Hepatitis Clinical Trials
69 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 69 trials
Recruiting
Phase 2
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Chronic Hepatitis B Infection
Aligos Therapeutics200 enrolled58 locationsNCT06963710
Recruiting
Phase 2
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Madrigal Pharmaceuticals, Inc.120 enrolled15 locationsNCT07335601
Recruiting
Phase 1Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Chronic Hepatitis Delta
Gilead Sciences107 enrolled15 locationsNCT07096193
Recruiting
Phase 2Phase 3
Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide
Chronic Hepatitis D
Mirum Pharmaceuticals, Inc.120 enrolled22 locationsNCT07454837
Recruiting
Phase 1Phase 2
A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease or With Metabolic Dysfunction-Associated Steatohepatitis (MASLD/MASH)
Metabolic Dysfunction-Associated Steatotic Liver DiseaseMetabolic Dysfunction-Associated Steatohepatitis
Regeneron Pharmaceuticals132 enrolled3 locationsNCT06836609
Recruiting
Phase 1Phase 2
Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV
Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)30 enrolled10 locationsNCT07040319
Recruiting
Phase 2
Belimumab in Autoimmune Hepatitis
Autoimmune Hepatitis
University Health Network, Toronto48 enrolled5 locationsNCT06381453
Recruiting
Phase 2
A Study of Hydronidone Capsules in Patients With Chronic Hepatitis B Virus-Related Liver Fibrosis
Chronic Hepatitis B-related Liver Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.150 enrolled1 locationNCT07417553
Recruiting
Phase 2
Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region
Hepatitis B, Chronic
AusperBio Therapeutics Inc.84 enrolled8 locationsNCT07370207
Recruiting
Phase 2
Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection
Chronic Hepatitis B
Gilead Sciences150 enrolled62 locationsNCT02932150
Recruiting
Phase 2
A Study to Evaluate the Safety of Hydronidone Capsules in Patients With Liver Fibrosis
Chronic Hepatitis B With Hepatic Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.200 enrolled1 locationNCT07364448
Recruiting
Phase 1Phase 2
Study of TGM-312-SC01 in Healthy Participants and Adults With MASH
Healthy ParticipantsMASH - Metabolic Dysfunction-Associated Steatohepatitis
Tangram Therapeutics Plc99 enrolled1 locationNCT07427680
Recruiting
Phase 2
A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Rivus Pharmaceuticals, Inc.180 enrolled33 locationsNCT07491458
Recruiting
Phase 2
VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B
Chronic Hepatitis B
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)50 enrolled1 locationNCT06092333
Recruiting
Phase 2
Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans
Liver FibrosisNonalcoholic Steatohepatitis
VA Office of Research and Development128 enrolled1 locationNCT05526144
Recruiting
Phase 1Phase 2
Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis
Decompensated Hepatitis B Cirrhosis
Beijing Tuohua Weiye Biotechnology Co., Ltd.76 enrolled1 locationNCT07413549
Recruiting
Phase 2
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Phase 2
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
Metabolic Dysfunction-Associated Steatohepatitis
Boston Pharmaceuticals42 enrolled35 locationsNCT06920043
Recruiting
Phase 2
A Study to Evaluate the Antiviral Activity and Immune Response of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.30 enrolled1 locationNCT06993480
Recruiting
Phase 2
A Multicenter, Randomized, Open, Parallel-designed Study to Evaluate the Efficacy and Safety of HRS-5635 Injection Alone or in Combination With Other Agents in Patients Treated for Chronic Hepatitis B
Chronic Hepatitis B
Fujian Shengdi Pharmaceutical Co., Ltd.369 enrolled1 locationNCT06425341