Phase 2 Hepatitis Clinical Trials
85 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 85 trials
Recruiting
Phase 2
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Madrigal Pharmaceuticals, Inc.120 enrolled17 locationsNCT07335601
Recruiting
Phase 2
Integrated Therapies for Alcohol Use in Alcohol-associated Liver Disease (ITAALD) Trial
Alcohol Associated Hepatitis
Samer Gawrieh216 enrolled6 locationsNCT07060638
Recruiting
Phase 1Phase 2
TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate
Chronic Hepatitis B
Michael Hoelscher81 enrolled6 locationsNCT06513286
Recruiting
Phase 1Phase 2
Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus
Chronic Hepatitis Delta
Gilead Sciences200 enrolled19 locationsNCT07096193
Recruiting
Phase 1Phase 2
Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV
Hepatitis C
National Institute of Allergy and Infectious Diseases (NIAID)30 enrolled10 locationsNCT07040319
Recruiting
Phase 2
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
Metabolic Dysfunction-Associated Steatohepatitis
Eccogene160 enrolled58 locationsNCT07288138
Recruiting
Phase 2
A Study of Chiglitazar in Patients With Metabolic Dysfunction-associated Steatohepatitis and Type 2 Diabetes Mellitus
MASH - Metabolic Dysfunction-Associated SteatohepatitisT2DM (Type 2 Diabetes Mellitus)
Shanghai Jiao Tong University School of Medicine300 enrolled17 locationsNCT07303803
Recruiting
Phase 2
Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
CirrhosisCirrhosis, LiverCirrhosis Due to Hepatitis B+5 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)256 enrolled13 locationsNCT05832229
Recruiting
Phase 2
VIR-2218 and Peginterferon Alfa-2a for Chronic Hepatitis B
Chronic Hepatitis B
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)50 enrolled1 locationNCT06092333
Recruiting
Phase 2
Phase 2 Study of AHB-137 in HBeAg Negative Chronic Hepatitis B (CHB) Participants in Asia Pacific Region
Hepatitis B, Chronic
AusperBio Therapeutics Inc.84 enrolled8 locationsNCT07370207
Recruiting
Phase 2
Digoxin In NASH (CODIN)
MASLDMASH - Metabolic Dysfunction-Associated SteatohepatitisFatty Liver Disease+5 more
Yale University144 enrolled2 locationsNCT06588699
Recruiting
Phase 2
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
Metabolic dysfunction-associated steatohepatitis (MASH)
Regeneron Pharmaceuticals120 enrolled71 locationsNCT05519475
Recruiting
Phase 2
A Multicenter Study of AHB-137 Injection Combined With Other Hepatitis B Drugs
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.200 enrolled1 locationNCT07069569
Recruiting
Phase 1Phase 2
Study of TGM-312-SC01 in Healthy Participants and Adults With MASH
Healthy ParticipantsMASH - Metabolic Dysfunction-Associated Steatohepatitis
Tangram Therapeutics Plc99 enrolled1 locationNCT07427680
Recruiting
Phase 2
A Study of CS060380 Tablets in Patients With MASH and Obesity
Metabolic dysfunction-associated steatohepatitis (MASH)Obesity
Cascade Pharmaceuticals, Inc120 enrolled12 locationsNCT07466017
Recruiting
Phase 2
A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Rivus Pharmaceuticals, Inc.180 enrolled31 locationsNCT07491458
Recruiting
Phase 2
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
Non-Alcoholic Fatty Liver DiseaseNon Alcoholic Steatohepatitis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)84 enrolled1 locationNCT03884075
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of AHB-137 Injection in Participants With Chronic Hepatitis B (CHB)
Chronic Hepatitis B
Ausper Biopharma Co., Ltd.60 enrolled1 locationNCT07137910
Recruiting
Phase 2
A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)
Chronic Hepatitis B Infection
Aligos Therapeutics200 enrolled58 locationsNCT06963710
Recruiting
Phase 2Phase 3
Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide
Chronic Hepatitis D
Mirum Pharmaceuticals, Inc.120 enrolled22 locationsNCT07454837