Phase 3 Hepatitis Clinical Trials

24 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 120 of 24 trials

Recruiting
Phase 2Phase 3

Study to Evaluate Switching to Brelovitug for the Treatment of CHD in Participants Receiving Bulevirtide

Chronic Hepatitis D
Mirum Pharmaceuticals, Inc.120 enrolled22 locationsNCT07454837
Recruiting
Phase 3

A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

MASH - Metabolic Dysfunction-Associated SteatohepatitisNASH - Nonalcoholic Steatohepatitis
Akero Therapeutics, Inc2,150 enrolled318 locationsNCT06528314
Recruiting
Phase 3

C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV

Hepatitis CHepatitis C, ChronicHepatitis C Virus Infection+1 more
Atea Pharmaceuticals, Inc.880 enrolled106 locationsNCT07037277
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
89bio, Inc.762 enrolled291 locationsNCT06419374
Recruiting
Phase 3

A Study to Evaluate Tobevibart+Elebsiran in Participants With Chronic HDV Infection Not Virologically Suppressed With Bulevirtide

Viral Hepatitis
Vir Biotechnology, Inc.150 enrolled36 locationsNCT07128550
Recruiting
Phase 3

Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

Hepatitis
Bausch Health Americas, Inc.350 enrolled48 locationsNCT07428538
Recruiting
Phase 3

A Clinical Trial Evaluating the Safety of Hydronidone Capsules in Patients With Hepatic Fibrosis and Liver Cirrhosis

Chronic Hepatitis B With Hepatic Fibrosis
Beijing Continent Pharmaceutical Co, Ltd.300 enrolled1 locationNCT07343778
Recruiting
Phase 3

A Trial Evaluating Brelovitug (BJT-778) vs Bulevirtide for the Treatment of Chronic Hepatitis Delta Infection (AZURE-2)

Chronic Hepatitis D Infection
Mirum Pharmaceuticals, Inc.172 enrolled44 locationsNCT07200908
Recruiting
Phase 3

A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)

Chronic Hepatitis D Infection
Mirum Pharmaceuticals, Inc.80 enrolled27 locationsNCT07298330
Recruiting
Phase 3

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
89bio, Inc.1,350 enrolled331 locationsNCT06318169
Recruiting
Phase 3

A Small Sample Prospective Clinical Study of Azvudine Tablets to Promote Clinical Cure in Patients With Chronic Hepatitis B

Chronic Hepatitis BAzvudine
Zhigang Ren120 enrolled1 locationNCT07307586
Recruiting
Phase 3

Using Hydroxychloroquine (HCQ) to Treat Steatohepatitis

Steatohepatitis, Nonalcoholic
National Taiwan University Hospital210 enrolled1 locationNCT07265297
Recruiting
Phase 3

Estrogen Administration for the Treatment of NASH in Postmenopausal Women

NASH - Nonalcoholic Steatohepatitis
Massachusetts General Hospital60 enrolled1 locationNCT04833140
Recruiting
Phase 2Phase 3

A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series

DiphtheriaPoliomyelitisHepatitis B+3 more
LG Chem1,186 enrolled1 locationNCT06947499
Recruiting
Phase 3

A Study to Investigate the Safety and Efficacy of Undiluted Intravenous Infusion of I.V.-Hepabig Inj.

Hepatitis B
GC Biopharma Corp105 enrolled8 locationsNCT05686759
Recruiting
Phase 3

Immunogenicity and Safety of I-HAV in Healthy Thai Children and Adolescents Lacking Protective Antibody After L-HAV

Hepatitis AHepatitis A Virus
Chiang Mai University36 enrolled1 locationNCT06978621
Active
Phase 3

A Study to Evaluate Tobevibart+Elebsiran in Chronic Hepatitis Delta Virus (HDV) Infection (ECLIPSE 1)

Chronic Hepatitis Delta Virus (HDV) Infection
Vir Biotechnology, Inc.120 enrolled10 locationsACTRN12625000416493
Recruiting
Phase 3

Short Course Steroids in Alcohol Associated Hepatitis

Alcoholic Hepatitis
Asian Institute of Gastroenterology, India146 enrolled2 locationsNCT06919458
Recruiting
Phase 3

Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV

Diptheria ImmunizationTetanus ImmunizationPertussis Immunization+3 more
Serum Institute of India Pvt. Ltd.1,557 enrolled9 locationsNCT06413121
Not Yet Recruiting
Phase 3

The effect of ertugliflozin in patients with nonalcoholic fatty liver disease (NAFLD) associated with type 2 diabetes mellitus.

Elevated liver enzymesNon alcoholic acute Steatohepatitis (NASH)Fatty liver diseases+1 more
Abdul Wali Khan University180 enrolled1 locationACTRN12624000032550