Phase 2 Hepatocellular Clinical Trials
226 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 226 trials
Recruiting
Phase 1Phase 2
A Phase Ib/II Trial to Evaluate the Efficacy and Safety of HH-009 for the Treatment of FGF19-positive Advanced or Unresectable HCC
Advanced or Unresectable Hepatocellular Carcinoma (HCC)
Huahui Health30 enrolled21 locationsNCT07547553
Recruiting
Phase 2
STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma
Hepatocellular Carcinoma
Canadian Cancer Trials Group140 enrolled12 locationsNCT06880523
Recruiting
Phase 2
Y-90 Treatment Response Using Transarterial Radioembolization
Liver CancerHepatocellular CarcinomaPrimary Liver Cancer+3 more
Thomas Jefferson University30 enrolled1 locationNCT07145801
Recruiting
Phase 2
A Study of BL-B01D1 Monotherapy, BL-B01D1 in Combination With Lenvatinib, BL-B01D1 in Combination With PD-1 Monoclonal Antibody, and BL-B01D1 in Combination With PD-1 Monoclonal Antibody and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
Sichuan Baili Pharmaceutical Co., Ltd.74 enrolled1 locationNCT06986785
Recruiting
Phase 2
Lenalidomide Plus Targeted Therapy and Immunotherapy for Refractory HCC
Hepatocellular Carcinoma (HCC)
Shunda Du32 enrolled1 locationNCT07639138
Recruiting
Phase 1Phase 2
GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC
Hepatocellular CarcinomaMetastatic Liver CancerLiver Cancer, Adult+1 more
Eureka Therapeutics Inc.60 enrolled8 locationsNCT04864054
Recruiting
Phase 2
Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
Urothelial CarcinomaEsophageal CarcinomaHepatocellular Carcinoma+28 more
Mayo Clinic50 enrolled1 locationNCT06265285
Recruiting
Phase 1Phase 2
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
Hepatocellular CarcinomaMetastatic Hepatocellular CarcinomaUnresectable Hepatocellular Carcinoma+4 more
Pfizer138 enrolled35 locationsNCT07227012
Recruiting
Phase 2
AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma
Hepatocellular Carcinoma
University of Florida12 enrolled1 locationNCT05669339
Recruiting
Phase 2
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis
Hepatocellular Carcinoma
Genentech, Inc.30 enrolled61 locationsNCT06096779
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Tolerability of Pumitamig Alone or In Combination With Ipilimumab in Participants With First-Line Advanced or Unresectable Hepatocellular Carcinoma (HCC) (ROSETTA HCC-206)
Hepatocellular Carcinoma (HCC)
Bristol-Myers Squibb198 enrolled59 locationsNCT07291076
Recruiting
Phase 2
Conversion Therapy With FOLFOX-HAIC Plus Lenvatinib And Tislelizumab For Hepatocellular Carcinoma With Vp3 Portal Vein Tumor Thrombus
Hepatocellular Carcinoma (HCC)Portal Vein Tumor Thrombus
First Hospital of China Medical University38 enrolled1 locationNCT07483359
Recruiting
Phase 2
Therasphere® and Systemic Therapy for Patients With Hepatocellular Carcinoma That is High-risk
Hepatocellular Carcinoma
Northwestern University200 enrolled7 locationsNCT05620771
Recruiting
Phase 2
Fostrox Plus Lenvatinib vs Lenvatinib in Advanced Hepatocellular Carcinoma After First-line Immunotherapy
Hepatocellular Carcinoma (HCC)
CHA University80 enrolled1 locationNCT07493668
Recruiting
Phase 1Phase 2
Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients
Hepatocellular CarcinomaRefractory Solid TumorPediatric Solid Tumor+3 more
St. Jude Children's Research Hospital64 enrolled2 locationsNCT05468359
Recruiting
Phase 2
18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
Gastric CancerOvarian CancerCholangiocarcinoma+7 more
National Cancer Institute (NCI)320 enrolled1 locationNCT06503146
Recruiting
Phase 2
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Breast CarcinomaUrothelial CarcinomaOvarian Carcinoma+26 more
Mayo Clinic27 enrolled1 locationNCT07285044
Recruiting
Phase 1Phase 2
Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial
Metastatic Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+1 more
National Cancer Institute (NCI)92 enrolled4 locationsNCT06811116
Recruiting
Phase 2
FOLFOX Combined With Durvalumab (MEDI4736), Bevacizumab, and Stereotactic Body Radiotherapy in Sequential Treatment of Potentially Resectable Locally Advanced Hepatocellular Carcinoma
Hepatocellular Carcinoma (HCC)
Tianjin Medical University Cancer Institute and Hospital30 enrolled1 locationNCT07012798
Recruiting
Phase 2
Tislelizumab Combined With Huaier Granule as First-line Treatment for Unresectable Hepatocellular Carcinoma
Hepatocellular Carcinoma (HCC)
Tongji Hospital94 enrolled1 locationNCT07413354