Early Phase 1 High Grade Glioma Clinical Trials
8 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–8 of 8 trials
Recruiting
Early Phase 1
Window Trial of Fluorescently Labeled Nivolumab-IRDye800 (Nivo800) in High Grade Glioma (HGG)
Brain CancerGliomaHigh Grade Glioma+1 more
Eben Rosenthal38 enrolled1 locationNCT07210632
Recruiting
Early Phase 1
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
High Grade GliomaDiffuse Intrinsic Pontine Glioma
Nationwide Children's Hospital15 enrolled21 locationsNCT04655404
Recruiting
Early Phase 1
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
GlioblastomaGlioblastoma MultiformeHigh Grade Glioma+6 more
Nationwide Children's Hospital15 enrolled18 locationsNCT06333899
Recruiting
Early Phase 1
Multiparametic Metabolic and Hypoxic PET/MRI for Disease Assessment in High Grade Glioma
High Grade Glioma
University of Alabama at Birmingham20 enrolled2 locationsNCT05632562
Recruiting
Early Phase 1
18F-Fluciclovine PET-MRI in High-grade Glioma
GliomaGlioma, MalignantDiffuse Glioma+2 more
Children's Hospital of Philadelphia30 enrolled1 locationNCT05553041
Recruiting
Early Phase 1
A Phase 0/1 Study of BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions
GlioblastomaHigh Grade Glioma
St. Joseph's Hospital and Medical Center, Phoenix82 enrolled2 locationsNCT06072586
Recruiting
Early Phase 1
Study of Sonodynamic Therapy in Participants with Recurrent High-Grade Glioma
High Grade Glioma
Nader Sanai30 enrolled1 locationNCT04559685
Recruiting
Early Phase 1
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG
GlioblastomaGliomaGlioma, Malignant+1 more
Nader Sanai12 enrolled1 locationNCT05773326