HIV Clinical Trials in Boston, Massachusetts

22 recruitingBoston, Massachusetts

Showing 120 of 22 trials

Recruiting
Phase 1Phase 2

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting
Phase 2

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Acute HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)48 enrolled36 locationsNCT05719441
Recruiting
Phase 3

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

HIV Infections
ViiV Healthcare332 enrolled89 locationsNCT06694805
Recruiting
Phase 1

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled7 locationsNCT06665646
Recruiting
Phase 2

A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV

HIV
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled22 locationsNCT06812494
Recruiting
Phase 2

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Mild Neurocognitive DisorderMajor Depressive DisorderHIV
National Institute of Allergy and Infectious Diseases (NIAID)186 enrolled40 locationsNCT06705478
Recruiting
Not Applicable

Implementing Depression and Adherence Treatment

DepressionHIVAdherence, Treatment+1 more
University of Miami10 enrolled3 locationsNCT07032363
Recruiting
Phase 4

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

HIVSubstance Use Disorder (SUD)Injection Drug Use
Massachusetts General Hospital100 enrolled2 locationsNCT07199335
Recruiting
Phase 2

Improving Physical Ability and Cellular Senescence Elimination in HIV

FrailtyHIVAging Problems+1 more
National Institute of Allergy and Infectious Diseases (NIAID)80 enrolled27 locationsNCT07144293
Recruiting
Phase 1Phase 2

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)36 enrolled12 locationsNCT06071767
Recruiting
Phase 2

Improving Coronary Vascular Health in Women

Metabolic DiseaseHIV-1-infectionCoronary Microvascular Dysfunction
Massachusetts General Hospital80 enrolled1 locationNCT06843902
Recruiting
Phase 1

Clinical Trial to Evaluate the Safety and Immunogenicity of a Priming Regimen of 426c.Mod.Core-C4b Followed by HxB2.WT.Core-C4b Boosts, Both Adjuvanted With 3M-052 AF + Alum, in Adult Participants Without HIV and in Overall Good Health

HIV
National Institute of Allergy and Infectious Diseases (NIAID)42 enrolled6 locationsNCT06796686
Recruiting
Phase 2

Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV

Anxiety DepressionMajor Depressive DisorderHIV
Massachusetts General Hospital120 enrolled1 locationNCT05570812
Recruiting

Infectious Disease (ID) Testing OUtreach in Carceral Hubs

HIV Infections
Boston Medical Center75 enrolled1 locationNCT06679751
Recruiting
Phase 2

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717
Recruiting
Not Applicable

Texting to Reduce Human Immunodeficiency Virus (HIV) Risk

HIV Infections
Boston University266 enrolled2 locationsNCT06088277
Recruiting
Not Applicable

Telehealth for Pain and Unhealthy Drinking Among PLWH

Chronic PainHIVUnhealthy Alcohol Use
Boston University385 enrolled1 locationNCT05503173
Recruiting

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

SYNGAP1-Related Intellectual DisabilityDLG4FOXP1+181 more
Simons Searchlight100,000 enrolled2 locationsNCT01238250
Recruiting
Not Applicable

A Mobile Gaming App to Improve Adherence to PrEP

Medication AdherenceHIV/AIDS
Rhode Island Hospital200 enrolled3 locationsNCT05762705
Recruiting
Phase 3

SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder

HIV InfectionsSubstance UseAdherence, Treatment+1 more
Brigham and Women's Hospital40 enrolled1 locationNCT05378399