RecruitingNot ApplicableNCT07032363

Implementing Depression and Adherence Treatment

Implementing Depression and Adherence Treatment in South Africa HIV Care


Sponsor

University of Miami

Enrollment

10 participants

Start Date

May 20, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare a core set and enhanced set of implementation strategies in increasing the reach of evidence-based treatments to patients with HIV and depression. The main questions it aims to answer are: What proportion of patients start an evidence-based treatment for depression (reach)? What percentage of patients show clinical improvement in depression and what percentage attain viral undetectability within one year (effectiveness)? Researchers will compare high and low reach clinics to further inform tailored implementation strategies for uptake and maintenance. Clinics will be randomized into one of two study arms: core versus enhanced strategies. In both arms, core strategies will be utilized. Enhanced clinics will also receive more resource-intensive training.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Core Implementation Strategies and Enhanced Implementation Strategies for people with aids, adherence, treatment, and other related conditions. The study is currently recruiting participants at 3 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERCore Implementation Strategies

* Task Sharing/Revise Professional Roles * Distribute educational materials/Dynamic Training/Address Stigma * Clinician Implementation Team Meetings * Partner with CoCT DoH * Champion * Audit and Feedback * Stage Scale Up/Tailoring

OTHEREnhanced Implementation Strategies

* Train the trainer * Ongoing supervision and consultation


Locations(3)

University of Miami

Miami, Florida, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

University of Cape Town

Cape Town, South Africa

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NCT07032363


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