Phase 1 Hodgkin's Lymphoma Clinical Trials

23 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 120 of 23 trials

Recruiting
Phase 1Phase 2

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

Non-Hodgkin's Lymphoma
Hoffmann-La Roche940 enrolled38 locationsNCT03075696
Recruiting
Phase 1

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaMantle Cell Lymphoma+5 more
British Columbia Cancer Agency24 enrolled7 locationsNCT06208735
Recruiting
Phase 1

Study for Subjects With Relapsed/Refractory Non- Hodgkin Lymphoma

Non Hodgkin's Lymphoma Refractory/Relapsed
ImmunityBio, Inc.20 enrolled2 locationsNCT05618925
Recruiting
Phase 1

Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma

Recurrent B-Cell Non-Hodgkin LymphomaRefractory B-Cell Non-Hodgkin LymphomaHigh Grade B-Cell Non-Hodgkin's Lymphoma+1 more
City of Hope Medical Center15 enrolled1 locationNCT05801913
Recruiting
Phase 1

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE

LymphomaNon-Hodgkin's LymphomaHodgkin's Disease+1 more
Baylor College of Medicine136 enrolled3 locationsNCT01555892
Recruiting
Phase 1Phase 2

Study of Atezolizumab Plus BEGEV Regimen in Relapsed or Refractory Hodgkin's Lymphoma Patients

Relapsed or Refractory Hodgkin's Lymphoma
Fondazione Italiana Linfomi - ETS122 enrolled32 locationsNCT05300282
Recruiting
Phase 1

Study to Evaluate Adverse Events, Change in Disease Activity, and How Intravenously Infused ABBV-291 Moves Through the Body in Adult Participants With Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma
AbbVie165 enrolled14 locationsNCT06667687
Recruiting
Phase 1

EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma

EBV-Related Hodgkin LymphomaEBV-Related Lymphoproliferative DisorderEBV Related Non-Hodgkin's Lymphoma
Baylor College of Medicine52 enrolled2 locationsNCT04664179
Recruiting
Phase 1

BAFFR-targeting CAR T Cells for Patients With Relapsed or Refractory B-NHL

Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
PeproMene Bio, Inc.36 enrolled6 locationsNCT05370430
Recruiting
Phase 1Phase 2

CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies

Acute Lymphoblastic LeukemiaChronic Lymphocytic LeukemiaNon-Hodgkin's Lymphoma
Ottawa Hospital Research Institute60 enrolled3 locationsNCT03765177
Recruiting
Phase 1Phase 2

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

Non-Hodgkin LymphomaNon-Hodgkin's LymphomaLymphomas Non-Hodgkin's B-Cell+2 more
Estrella Biopharma, Inc.21 enrolled2 locationsNCT06343311
Recruiting
Phase 1

CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)

Non-Hodgkin LymphomaHodgkin's Lymphoma
Baylor College of Medicine60 enrolled2 locationsNCT02917083
Recruiting
Phase 1

CART19 Cells Effects in Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia and Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma, RelapsedNon-Hodgkin's Lymphoma RefractoryRelapsed or Refractory B-cell Acute Lymphoblastic Leukemia
Institute of Hematology and Blood Transfusion, Czech Republic10 enrolled1 locationNCT05054257
Recruiting
Phase 1Phase 2

A Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy Study of MBS303 in B-Cell NHL

Non-Hodgkin's Lymphoma
Beijing Mabworks Biotech Co., Ltd.132 enrolled1 locationNCT05806099
Recruiting
Phase 1

On the Safety, Tolerability, and Efficacy of UTAA09 Injection in the Treatment of Lymphoma

Recurrent or Refractory B-cell Non Hodgkin's Lymphoma
The First Affiliated Hospital with Nanjing Medical University10 enrolled1 locationNCT06503211
Recruiting
Phase 1

A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma

Hodgkin's LymphomaAnaplastic Large Cell Lymphoma
Ruijin Hospital32 enrolled1 locationNCT06494371
Recruiting
Phase 1

TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors

Advanced Solid TumorNon-Hodgkin's Lymphoma, RelapsedNon-Hodgkin's Lymphoma Refractory
Tarapeutics Science Inc.26 enrolled1 locationNCT05650580
Recruiting
Phase 1Phase 2

Chidamide Bridging for CAR-T Therapy

Non-Hodgkin's Lymphoma
Chinese PLA General Hospital120 enrolled13 locationsNCT05370547
Recruiting
Phase 1Phase 2

A Trial of SHR-A1912 Combined With Other Therapies in B-cell Non-Hodgkin 's Lymphoma

B-cell Non-Hodgkin's Lymphoma
Shanghai Hengrui Pharmaceutical Co., Ltd.132 enrolled1 locationNCT06104553
Recruiting
Phase 1Phase 2

Clinical Study of U16 in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Relapsed or Refractory Non-Hodgkin's Lymphoma
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd100 enrolled2 locationsNCT05768529