Phase 2 Huntington Disease Clinical Trials

8 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 18 of 8 trials

Recruiting
Phase 2Phase 3

Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's Disease

Huntington DiseaseHuntingtons Disease
Skyhawk Therapeutics, Inc.120 enrolled12 locationsNCT06873334
Recruiting
Phase 2Phase 3

Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

Huntington Disease
Skyhawk Therapeutics, Inc.400 enrolled4 locationsNCT07378644
Recruiting
Phase 1Phase 2

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

Huntington Disease
Hoffmann-La Roche53 enrolled5 locationsNCT06826612
Recruiting
Phase 1Phase 2

Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

Huntington Disease
Leslie Thompson21 enrolled1 locationNCT07451613
Recruiting
Phase 1Phase 2

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Spinocerebellar Ataxia Type 3Spinocerebellar Ataxia Type 1Huntington Disease
Vico Therapeutics B. V.68 enrolled14 locationsNCT05822908
Recruiting
Phase 2

The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's Disease

Huntington Disease
Oslo University Hospital120 enrolled1 locationNCT06853743
Recruiting
Phase 2

A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers

Huntington Disease
Western Sydney Local Health District160 enrolled5 locationsNCT05509153
Recruiting
Phase 2

Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's Disease

Huntington Disease
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla24 enrolled3 locationsNCT04478734