Hypothermia Clinical Trials

27 recruitingLast updated: May 21, 2026

There are 27 actively recruiting hypothermia clinical trials across 22 countries. Studies span Not Applicable. Top locations include Houston, Texas, United States, Miami, Florida, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Hypothermia Trials at a Glance

27 actively recruiting trials for hypothermia are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Houston, Miami, and Beijing. Lead sponsors running hypothermia studies include Azienda Sanitaria dell'Alto Adige, Beijing Anzhen Hospital, and Assistance Publique - Hôpitaux de Paris.

Browse hypothermia trials by phase

About Hypothermia Clinical Trials

Looking for clinical trials for Hypothermia? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypothermia trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypothermia clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting

Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass

Cardiopulmonary BypassHypothermia; AnesthesiaDepth of Anesthesia Monitoring
Sakarya University60 enrolled1 locationNCT07508579
Recruiting

ESOTIP-TEE: Defining an Easy Landmark to Guide Correct Esophageal Probe Placement With Transesophageal Echocardiography

HypothermiaMonitoringEsophageal Temperature
Institute of Mountain Emergency Medicine30 enrolled1 locationNCT07574736
Recruiting
Not Applicable

Effect of Thermoregulation Bundle Applied at Birth on Neonatal Physiological Parameters and Breastfeeding

Neonatal HypothermiaThermoregulationNeonatal Adaptation
Istanbul University - Cerrahpasa140 enrolled1 locationNCT07453264
Recruiting
Not Applicable

PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)

Cardiopulmonary ResuscitationDeath, Sudden, CardiacOut-of-hospital cardiac arrest+1 more
Singapore General Hospital50 enrolled1 locationNCT07421882
Recruiting
Not Applicable

Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)

Cardiac Arrest, Out-Of-HospitalHypoxia-Ischemia, BrainHypothermia, Induced
University of Michigan900 enrolled60 locationsNCT05376267
Recruiting
Not Applicable

Impact of a Global Warming Strategy of the Patient on the Prevalence of Hypothermia in the Recovering Room

Perioperative/Postoperative ComplicationsHypothermia; Anesthesia
Poitiers University Hospital174 enrolled1 locationNCT06551558
Recruiting
Not Applicable

Arch-Clamping Technique Under Mild Hypothermia in Treating With Acute Type A Aortic Dissection

HypothermiaAcute Type A Aortic DissectionTotal Aortic Arch Replacement+2 more
Beijing Anzhen Hospital306 enrolled1 locationNCT07150559
Recruiting

Long Term Follow-up of Cardiac Arrest Survivors Exposed to Ultra-rapid Cooling

Cardiac Arrest (CA)Resuscitated Sudden Cardiac DeathPost Cardiac Arrest Patient Who Was Treated by Hypothermia Protocol
Assistance Publique - Hôpitaux de Paris12 enrolled2 locationsNCT07028372
Recruiting
Not Applicable

Effects of Intraoperative Targeted Temperature Management on Incidence of Postoperative Delirium and Long-term Survival

HypothermiaCancer SurgeryDelirium+1 more
Peking University First Hospital3,992 enrolled36 locationsNCT06256354
Recruiting

Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in Neonates

Preterm Less Than 32wks With IVH, WMI/PVLLate Preterm or Term (37-42wks) With Neonatal Encephalopathy Treated With Hypothermia for HIE
Brigham and Women's Hospital60 enrolled1 locationNCT07275021
Recruiting
Not Applicable

Prehospital Resuscitation Intranasal Cooling Effectiveness Survival Study 2

HypothermiaVentricular FibrillationOut-of-hospital cardiac arrest
Karolinska Institutet1,022 enrolled11 locationsNCT06025123
Recruiting
Not Applicable

The Effect of Heating the Intensive Care Room in the Early Postoperative Period on Patient Outcomes

Hypothermia Following AnesthesiaAbdominal Surgery Complications
Cukurova University70 enrolled1 locationNCT07137143
Recruiting

Justifying humidification management options for infants delivered extremely premature- when and why? A randomised controlled trial. (Y HUMIDIFY).

Hyperthermia in extremely premature infantsSkin integrity/ skin injuries in extremely premature infantsHypothermia in extremely premature infants+2 more
Royal Brisbane and Women's Hospital, Metro North Queensland Health378 enrolled1 locationACTRN12625000726459
Recruiting
Not Applicable

Safety and Efficacy of Selective Intra-Arterial Cooling Infusion Combined With EVT in Acute Ischemic Stroke

HypothermiaAcute Ischemic Stroke
Beijing Shijitan Hospital, Capital Medical University258 enrolled9 locationsNCT06485427
Recruiting
Not Applicable

Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss

Occupational HealthNoise-induced hearing lossOccupational Exposure+5 more
Restorear Devices LLC116 enrolled1 locationNCT06729632
Recruiting

Investigation of the Mechanisms of the Tendency to Hypothermia in Newborns and Premature Neonates

neonateNeonatal HypothermiaBrown Adipose Tissue+3 more
University of Pecs100 enrolled2 locationsNCT06803069
Recruiting

Prognostic Biomarkers for Selective Intra-Arterial Cooling Infusion Combined with Endovascular Thrombectomy in Acute Ischemic Stroke Based on Proteomics and Metabolomics.

StrokeHypothermia Treatment
Capital Medical University258 enrolled1 locationNCT06665386
Recruiting
Not Applicable

Blood Warming in Preterm Infants to Decrease Hypothermia

HypothermiaBlood Transfusion ComplicationPreterm Birth
University of South Carolina140 enrolled1 locationNCT05170633
Recruiting

Quantification of Brain and Kidney Perfusion Before, During, and After Hypothermia Treatment in Neonates With Perinatal Asphyxia Using Contrast-enhanced Ultrasound

Hypothermia TreatmentPerinatal AsphyxiaGestational Age Min. 36SSW
University of Erlangen-Nürnberg Medical School20 enrolled1 locationNCT06611254
Recruiting

Evaluation of The Relationship Between Perioperative Hypothermia and Emergence Agitation

Postoperative ComplicationsHypothermia; AnesthesiaAgitation, Emergence+1 more
Kocaeli City Hospital120 enrolled1 locationNCT06543134