Idiopathic Scoliosis Clinical Trials

59 recruitingLast updated: June 18, 2026

There are 59 actively recruiting idiopathic scoliosis clinical trials across 15 countries. Studies span Not Applicable, Phase 3, Phase 4. Top locations include New York, New York, United States, Hong Kong, Hong Kong, Helsinki, Finland. Updated daily from ClinicalTrials.gov.


Idiopathic Scoliosis Trials at a Glance

59 actively recruiting trials for idiopathic scoliosis are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 37 trials, with the heaviest enrollment activity in New York, Hong Kong, and Helsinki. Lead sponsors running idiopathic scoliosis studies include Second Affiliated Hospital of Wenzhou Medical University, The First Affiliated Hospital of Zhejiang Chinese Medical University, and The Hong Kong Polytechnic University.

Browse idiopathic scoliosis trials by phase

Treatments under study

About Idiopathic Scoliosis Clinical Trials

Looking for clinical trials for Idiopathic Scoliosis? There are currently 18 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Idiopathic Scoliosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Idiopathic Scoliosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 59 trials

Recruiting

UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study

Adolescent Idiopathic Scoliosis (AIS)Neuromuscular Scoliosis
University of Colorado, Denver500 enrolled1 locationNCT07634627
Recruiting

Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Complex

HyperkyphosisHyperlordosisCongenital Scoliosis+2 more
Aesculap AG200 enrolled2 locationsNCT05281757
Recruiting
Not Applicable

A Study to Evaluate a New Semi-rigid Brace, the RESILIENT Brace by Thinks Works, as a Way to Limit Curve Worsening in Kids With Idiopathic Scoliosis.

Idiopathic Scoliosis
Thinks Works, PBC30 enrolled1 locationNCT07574632
Recruiting
Not Applicable

Characterization of Visual Perception Impairments in Patients With Idiopathic Scoliosis

Idiopathic Scoliosis
Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française70 enrolled1 locationNCT07356999
Recruiting
Not Applicable

Effect of Vitamin A Supplementation on Idiopathic Scoliosis

Vitamin A deficiencyIdiopathic Scoliosis
Second Affiliated Hospital of Wenzhou Medical University140 enrolled1 locationNCT07335991
Recruiting
Not Applicable

Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing

Sleep-disordered breathing (SDB)Idiopathic ScoliosisObstructive Sleep Apnea (OSA)
Second Affiliated Hospital of Wenzhou Medical University160 enrolled1 locationNCT07332780
Recruiting
Not Applicable

Effect of Bright Light Therapy on Idiopathic Scoliosis

Idiopathic ScoliosisDelayed Sleep PhaseEveningness
Second Affiliated Hospital of Wenzhou Medical University120 enrolled1 locationNCT07424703
Recruiting
Not Applicable

Support System Design for Adolescent Scoliosis Orthosis Wear

Adolescent Idiopathic Scoliosis (AIS)Adherence
Shanghai Jiao Tong University School of Medicine18 enrolled1 locationNCT07574229
Recruiting
Phase 3

Evaluation of Analgesia for Spine Fusion Elective Surgery in Children

Idiopathic Scoliosis
Senthil Sadhasivam500 enrolled2 locationsNCT06626503
Recruiting
Phase 3

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

Adolescent Idiopathic ScoliosisAdolescent Idiopathic Scoliosis (AIS)Neuromuscular Scoliosis
University of California, San Francisco42 enrolled1 locationNCT07561827
Recruiting
Not Applicable

Machine Learning Prediction of Disease Progression in Adolescent Idiopathic Scoliosis

Adolescence Idiopathic Scoliosis
Istanbul University30 enrolled1 locationNCT07556042
Recruiting
Not Applicable

Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)

Adolescent Idiopathic Scoliosis
Columbia University87 enrolled1 locationNCT03292601
Recruiting
Not Applicable

Basic Body Awareness Therapy Added to Scoliosis-Specific Exercise in Adolescents With Scoliosis

Adolescent Idiopathic Scoliosis (AIS)
Gözde Yagci (Gür)40 enrolled1 locationNCT07500883
Recruiting

Using Radiation-free Ultrasound for Screening Scoliosis Among School Children in Hong Kong to Reduce Unnecessary X-ray Exposure

Adolscent Idiopathic Scoliosis
Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University160 enrolled1 locationNCT07490886
Recruiting
Not Applicable

Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis

Adolescent Idiopathic Scoliosis (AIS)
University of California, San Francisco64 enrolled1 locationNCT06365892
Recruiting

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

SpondylolisthesisAdolescent Idiopathic ScoliosisCongenital Scoliosis+3 more
Boston Children's Hospital700 enrolled10 locationsNCT05071144
Recruiting
Not Applicable

3D, Dynamic and Mechanically-informed Decision Making in AIS

Adolescent Idiopathic Scoliosis
Universitaire Ziekenhuizen KU Leuven100 enrolled1 locationNCT04761549
Recruiting
Not Applicable

Resisted Inspiratory Muscle Training Applied in Addition to PSSE-Schroth Exercises

Adolescence Idiopathic Scoliosis
Hacettepe University45 enrolled1 locationNCT07321600
Recruiting
Not Applicable

Psychological Assessment of Scoliosis Patients Undergoing Surgical Management

Mental HealthAdolescent Idiopathic Scoliosis (AIS)
Montefiore Medical Center120 enrolled1 locationNCT05774002
Recruiting
Not Applicable

Personalized Prevention and Treatment Strategies for Adolescent Idiopathic Scoliosis Via a Comprehensive Health Management Platform

Adolescent Idiopathic Scoliosis (AIS)
Hangzhou Medical College76 enrolled1 locationNCT06314594