Obstructive Sleep Apnea (OSA) Clinical Trials

33 recruiting

Obstructive Sleep Apnea (OSA) Trials at a Glance

31 actively recruiting trials for obstructive sleep apnea (osa) are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 15 trials, with the heaviest enrollment activity in Bethesda, San Diego, and Ghent. Lead sponsors running obstructive sleep apnea (osa) studies include Inspire Medical Systems, Inc., ResMed Ltd, and Uniformed Services University of the Health Sciences.

Browse obstructive sleep apnea (osa) trials by phase

Treatments under study

About Obstructive Sleep Apnea (OSA) Clinical Trials

Looking for clinical trials for Obstructive Sleep Apnea (OSA)? There are currently 33 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Obstructive Sleep Apnea (OSA) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Obstructive Sleep Apnea (OSA) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 31 trials

Recruiting
Phase 4

Endotype DIrected Treatment for OSA in Down Syndrome

Down SyndromeObstructive Sleep Apnea (OSA)
University of Arizona200 enrolled5 locationsNCT07280468
Recruiting

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

Obstructive Sleep Apnea (OSA)
Inspire Medical Systems, Inc.70 enrolled5 locationsNCT07113288
Recruiting
Not Applicable

Digital-supported Orofacial Myofunctional Therapy in OSA

Obstructive Sleep Apnea (OSA)
Hong Kong Metropolitan University60 enrolled1 locationNCT07292922
Recruiting
Not Applicable

Effects of Frequency Adjustment in Functional Electrical Stimulation on Genioglossus Muscle Activity

SnoringObstructive Sleep Apnea (OSA)
Seoul National University Bundang Hospital28 enrolled1 locationNCT07466888
Recruiting
Not Applicable

Telemonitoring With CPAP in Severe Obstructive Sleep Apnea in Primary Health Care

Obstructive Sleep Apnea (OSA)
Federal University of São Paulo200 enrolled1 locationNCT07464262
Recruiting

Multimodal Deep Learning Model for Predicting the Apnea-Hypopnea Index in Obstructive Sleep

Obstructive Sleep Apnea (OSA)Polysomnography
Fu Jen Catholic University150 enrolled1 locationNCT07447999
Recruiting
Not Applicable

High-Flow Nasal Cannula for Preventing Hypoxia During Sedated Endoscopy in High-Risk Obstructive Sleep Apnea Patients

Esophageal CancerHypoxiaGastric Cancer (Diagnosis)+1 more
Zhejiang University600 enrolled3 locationsNCT07307560
Recruiting
Phase 1Phase 2

Low-Tech Treatments for Obstructive Sleep Apnea

Traumatic Brain Injury (TBI)Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences60 enrolled1 locationNCT07301710
Recruiting
Not Applicable

CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial

Mild Cognitive ImpairmentObstructive Sleep Apnea (OSA)
National University Hospital, Singapore260 enrolled1 locationNCT06983769
Recruiting

Portable Sleep Monitors in Children With Autism Spectrum Disorder

Autism Spectrum Disorder (ASD)Obstructive Sleep Apnea (OSA)
Lena Xiao20 enrolled1 locationNCT07367022
Recruiting

VIdeo Clips for Diagnostic Evaluation of Obstructive Sleep Apnea in Children

Obstructive Sleep Apnea (OSA)
Children's Hospital of Eastern Ontario625 enrolled4 locationsNCT06801366
Recruiting

A Modified Baveno Classification of Obstructive Sleep Apnoea Based on Sleepiness and Cardiovascular Scores

Obstructive Sleep Apnea (OSA)
Wissenschaftliches Institut Bethanien e.V1,800 enrolled18 locationsNCT06861686
Recruiting
Not Applicable

IOA Preventing Occlusal Changes With MAD Use

SnoringObstructive Sleep Apnea (OSA)Sleep Related Breathing Disorder+4 more
Isabel Moreno Hay30 enrolled1 locationNCT07103941
Recruiting
Not Applicable

Hypoglossal Nerve Stimulation for the Treatment of Adult Obstructive Sleep Apnea

Obstructive Sleep Apnea (OSA)
XII Medical30 enrolled5 locationsNCT07049744
Recruiting
Not Applicable

Telehealth for Sleep Apnea: Effectiveness, Implementation, and Cost in the Military Health System

Obstructive Sleep Apnea (OSA)
Uniformed Services University of the Health Sciences160 enrolled2 locationsNCT07121452
Recruiting

EURO-STIM Registry

Obstructive Sleep ApneaObstructive Sleep Apnea (OSA)
Inspire Medical Systems, Inc.1,000 enrolled21 locationsNCT06971796
Recruiting
Not Applicable

Oromyofunctional Training: an Innovative Rehabilitation Program for Pediatric Obstructive Sleep Apnea

Obstructive Sleep Apnea (OSA)Orofacial Myofunctional Disorders
University Ghent90 enrolled1 locationNCT07129967
Recruiting
Not Applicable

Oromyofunctional Therapy: a Rehabilitation Program for OSA in Children With Down Syndrome and Prader-Willi Syndrome

Obstructive Sleep Apnea (OSA)Orofacial Myofunctional Disorders
University Ghent60 enrolled1 locationNCT07122505
Recruiting
Not Applicable

Validating a Novel Driving Simulation-based MWT Against the Standard MWT in an OSA-cohort Challenged by CPAP-withdrawal

Obstructive Sleep Apnea (OSA)CPAP TreatmentCPAP+3 more
Stefan Lakämper54 enrolled1 locationNCT06872593
Recruiting
Not Applicable

Assessment of Circuit Rebreathing During CPAP Therapy

Obstructive Sleep Apnea (OSA)
Brigham and Women's Hospital13 enrolled1 locationNCT07062770