Phase 1 Immune System Clinical Trials

8 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 18 of 8 trials

Recruiting
Phase 1Phase 2

A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus

Metabolic DiseaseDiabetes Mellitus, Type 1Type 1 Diabetes+14 more
Otsuka Pharmaceutical Factory, Inc.13 enrolled1 locationNCT06575426
Not Yet Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PRO-203 in Healthy Volunteers

Inflammatory and immune system
Prolium Biosicence, Inc.50 enrolled1 locationACTRN12625001266459
Recruiting
Phase 1

A First-in-Human Phase I Trial of OX118 in Healthy Volunteers

Immune System
Oxion Biologics AB32 enrolled1 locationNCT07020156
Recruiting
Phase 1

A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

NeoplasmsMultiple MyelomaCardiovascular Diseases+11 more
OriCell Therapeutics Co., Ltd.81 enrolled1 locationNCT06271252
Recruiting
Phase 1Phase 2

An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of VCTX211 Combination Product in Subjects With T1D

Diabetes MellitusMetabolic DiseaseDiabetes Mellitus, Type 1+4 more
CRISPR Therapeutics AG40 enrolled2 locationsNCT05565248
Completed
Phase 1

A study to test the safety of MYNFLU001 Influenza Vaccine in Healthy Adults

Inflammatory and immune systemInfluenza
Mynvax Pty. Ltd.45 enrolled1 locationACTRN12623000925640
Completed
Phase 1

A First-In-Human study to evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Ascending Doses of NT-0249 in Healthy Volunteers.

Inflammation and Immune SystemInflammation
NodThera72 enrolled1 locationACTRN12622000195752
Completed
Phase 1

Dose escalation, placebo-controlled phase 1 study to assess the safety and tolerability of CSL324 in healthy adults

Inflammatory and immune system disorders
CSL Limited58 enrolled1 locationACTRN12616000846426