Intestinal Disease Clinical Trials

38 recruitingLast updated: June 18, 2026

There are 38 actively recruiting intestinal disease clinical trials across 26 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3. Top locations include Boston, Massachusetts, United States, Chicago, Illinois, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Intestinal Disease Trials at a Glance

38 actively recruiting trials for intestinal disease are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in Boston, Chicago, and Houston. Lead sponsors running intestinal disease studies include Boston Children's Hospital, Christopher C. Thompson, MD, MSc, and Baylor Research Institute.

Browse intestinal disease trials by phase

Treatments under study

About Intestinal Disease Clinical Trials

Looking for clinical trials for Intestinal Disease? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Intestinal Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Intestinal Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 38 trials

Recruiting
Not Applicable

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

Postoperative ComplicationsAnastomotic LeaksAnastomotic Complication+8 more
Medtronic - MITG137 enrolled9 locationsNCT07351071
Recruiting
Phase 3

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

Colorectal NeoplasmsNeoplasms by SiteGastrointestinal Neoplasms+7 more
Pfizer800 enrolled228 locationsNCT07222800
Recruiting
Not Applicable

Implementation of a Pediatric ERAS-based Protocol in Intestinal Resection With Primary Anastomosis

Intestinal DiseasesIntestinal Resection
Michał Pasierbek120 enrolled9 locationsNCT07504549
Recruiting

Evaluation of Patients With Gastrointestinal Disease

Gastrointestinal DiseasesLower GI Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)4,000 enrolled1 locationNCT05041374
Recruiting
Phase 4

Evaluation of Efficacy of Skål Pro Powder on Symptoms of Irritable Bowel Syndrome

Pathologic ProcessesIntestinal DiseaseGastrointestinal Diseases+5 more
EP Plus Group Sdn Bhd60 enrolled1 locationNCT06271538
Recruiting
Not Applicable

Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet

Cystic Fibrosis (CF)Cystic Fibrosis Gastrointestinal Disease
Dartmouth-Hitchcock Medical Center20 enrolled2 locationsNCT07223255
Recruiting
Not Applicable

Exclude or Expose in Irritable Bowel Syndrome: What Works for Whom and How?

Gastrointestinal DiseaseIntestinal DiseasesIrritable Bowel Syndrome (IBS)
University of Melbourne235 enrolled1 locationNCT06940596
Recruiting
Phase 1

First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors

Metastatic CancerGastrointestinal NeoplasmsGastrointestinal Diseases+2 more
IDRX, Inc., a wholly owned subsidiary of GSK, LLC278 enrolled31 locationsNCT05489237
Recruiting

Study of Normal Intestinal Development and Disease in Premature and Term Neonates

Necrotizing EnterocolitisIntestinal DiseaseNEC+1 more
Boston Children's Hospital100 enrolled1 locationNCT06681129
Recruiting
Phase 1Phase 2

Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.

HealthyGastrointestinal DiseasesAutism Spectrum Disorder
Chang Gung Memorial Hospital60 enrolled1 locationNCT06290258
Recruiting

Eosinophilic Gastrointestinal Disorders Registry

eosinophilic esophagitisEosinophilic GastroenteritisEosinophilic Colitis+1 more
Ann & Robert H Lurie Children's Hospital of Chicago500 enrolled1 locationNCT05199532
Recruiting
Not Applicable

H. Pylori Eradication With Argon Plasma During Endoscopy

Helicobacter Pylori InfectionHelicobacter PyloriH.Pylori Infection+2 more
Christopher C. Thompson, MD, MSc20 enrolled1 locationNCT06529159
Recruiting
Not Applicable

Trans-nasal Endoscopy for Bariatric Patients

ObesityGastrointestinal DiseasesObese+2 more
Christopher C. Thompson, MD, MSc100 enrolled1 locationNCT06200961
Recruiting
Not Applicable

Foregut Leaks-Role of Microbiome

Gastrointestinal Diseases
Baylor Research Institute50 enrolled1 locationNCT07424469
Recruiting
Not Applicable

Elemental 028 Extra Case Studies

MalabsorptionAllergiesGastrointestinal Disease+3 more
Nutricia UK Ltd30 enrolled1 locationNCT06877923
Recruiting
Not Applicable

Virtual Reality for Non-cardiac Chest Pain

Gastrointestinal DiseasesChest Pain
Mayo Clinic10 enrolled1 locationNCT06262126
Recruiting
Phase 4

Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection

Intestinal Disease
University of California, Irvine128 enrolled1 locationNCT06112353
Recruiting
Phase 4

CURE-H. Pylori: A Trial on the Combination of Anti-Ulcerants and Levofloxacin-Based Therapy for Helicobacter Pylori Eradication

H.Pylori InfectionH. Pylori Gastrointestinal DiseaseH.Pylori Eradication Rate
Dow University of Health Sciences942 enrolled1 locationNCT07344506
Recruiting
Not Applicable

Ritual Synbiotic+, a Dietary Supplement Designed to Impact Gastrointestinal Health, Mood, and Behavior in Women

Gastrointestinal Disease Symptoms
Colorado State University60 enrolled1 locationNCT06834984
Recruiting

Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

Food allergyEosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease
Children's Hospital Medical Center, Cincinnati5,000 enrolled1 locationNCT00267501