Phase 2 Kidney Cancer Clinical Trials

15 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 115 of 15 trials

Recruiting
Phase 1Phase 2

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Colorectal, CancerHepatocellular CarcinomaMelanoma+15 more
7 Hills Pharma, LLC126 enrolled5 locationsNCT06362369
Recruiting
Phase 2

Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus

Renal Cell CarcinomaKidney CancerRenal Cancer+1 more
University of Colorado, Denver17 enrolled3 locationsNCT05969496
Recruiting
Phase 2

Study of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations

Metastatic Renal Cell CarcinomaRenal Cell CarcinomaKidney Cancer+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins20 enrolled1 locationNCT03786796
Recruiting
Phase 2

A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma

Metastatic Renal Cell CarcinomaRenal Cell CarcinomaKidney Cancer+3 more
Stephanie Berg25 enrolled2 locationsNCT07123090
Recruiting
Phase 2

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

Renal Cell CarcinomaKidney CancerRenal Carcinoma+1 more
Dana-Farber Cancer Institute32 enrolled3 locationsNCT07397611
Recruiting
Phase 2

Comprehensive Multimodal Prehabilitation Alone or With Neoadjuvant Therapy Before Major Cancer Surgery

Bladder CancerKidney CancersOvarian Cancer (OvCa)+1 more
The Methodist Hospital Research Institute148 enrolled1 locationNCT07050771
Recruiting
Phase 1Phase 2

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

Colorectal, CancerEsophageal CancerOvarian Cancer+12 more
Essen Biotech83 enrolled1 locationNCT07410676
Recruiting
Phase 1Phase 2

Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors

Breast CancerColorectal, CancerGastric Cancer+4 more
Hadassah Medical Organization50 enrolled1 locationNCT00722228
Recruiting
Phase 2

NSAID Use After Robotic Partial Nephrectomy

Kidney CancerRenal CancerRenal Neoplasm
University of Miami110 enrolled1 locationNCT05842044
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression

Triple-Negative Breast CancerColorectal, CancerLung Cancer+14 more
A2 Biotherapeutics Inc.240 enrolled10 locationsNCT06682793
Recruiting
Phase 2

Ivonescimab in the Treatment of Multiple Advanced Tumors

Urothelial CarcinomaSarcomaKidney Cancer+16 more
Fudan University400 enrolled1 locationNCT06683846
Recruiting
Phase 2

CYTO Reductive Surgery in Kidney Cancer Plus Immunotherapy and Targeted Kinase Inhibition

Renal Cell CarcinomaKidney Cancer
Mark Stein48 enrolled4 locationsNCT04322955
Recruiting
Phase 2

A study of EnGeneIC Dream Vectors (EDV's) packaged with the chemotherapy, E-EDV-D682 given simultaneously as non-targeted EDVs carrying an immune enhancer called EDV-GC, in participants with advanced epidermal growth factor expressing cancers whose disease has progressed after one or two treatment regimes, or where other standard therapies are not appropriate. (EGFR EDV-D682/GC Trial)

Bladder/Kidney cancerEGFR expressing solid tumorsLung cancer (NSCLC and Mesothelioma)
EnGeneIC Pty Limited160 enrolled2 locationsACTRN12625000203459
Recruiting
Phase 2

Proteomic Guided First-line Precision Treatment of Renal Clear Cell Carcinoma

Renal Cell CarcinomaKidney CancerRenal Clear Cell Carcinoma
Fudan University66 enrolled1 locationNCT06211790
Terminated
Phase 2

Denosumab and Pembrolizumab in Clear Cell Renal Carcinoma

Metastatic Kidney CancerRenal Cell Carcinoma, Clear Cell
Australian and New Zealand Urogenital and Prostate Cancer Trials Group70 enrolled15 locationsACTRN12618000132246