Large Vessel Occlusion Clinical Trials

16 recruitingLast updated: May 21, 2026

There are 16 actively recruiting large vessel occlusion clinical trials across 8 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Tianjin, Tianjin Municipality, China, Barcelona, Spain, Budapest, Hungary. Updated daily from ClinicalTrials.gov.


Large Vessel Occlusion Trials at a Glance

16 actively recruiting trials for large vessel occlusion are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Tianjin, Barcelona, and Budapest. Lead sponsors running large vessel occlusion studies include Tianjin Huanhu Hospital, Anaconda Biomed S.L., and Changhai Hospital.

Browse large vessel occlusion trials by phase

About Large Vessel Occlusion Clinical Trials

Looking for clinical trials for Large Vessel Occlusion? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Large Vessel Occlusion trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Large Vessel Occlusion clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Not Applicable

Non-invasive Vagus Nerve Stimulation to Reduce Inflammation and Brain Injury Blood Biomarkers Following an Acute Ischemic Stroke

Acute Ischemic StrokeLarge Vessel Occlusion
Washington University School of Medicine65 enrolled1 locationNCT07404852
Recruiting
Phase 2

Intra-arterial Methylprednisolone After Endovascular Thrombectomy

ThrombectomyIschemia StrokeLarge Vessel Occlusion
Tang-Du Hospital210 enrolled1 locationNCT07516522
Recruiting
Phase 3

Tenecteplase Before Interhospital Transfer for EVT in Acute Anterior Circulation LVO at 4.5-24 Hours

Acute Ischemic StrokeLarge Vessel OcclusionTransportation of Patients
Xuanwu Hospital, Beijing572 enrolled2 locationsNCT07253181
Recruiting
Phase 2

Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy

Acute Ischemic Stroke From Large Vessel Occlusion
University of Pennsylvania20 enrolled1 locationNCT06904911
Recruiting

Prospective Registry of Endovascular Thrombectomy for eXtra-Large Ischemic Stroke

Acute Ischemic Stroke AISAcute Ischemic Stroke From Large Vessel Occlusion
Zhongming Qiu1,000 enrolled1 locationNCT06210633
Recruiting
Not Applicable

Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter

Acute Ischemic Stroke From Large Vessel Occlusion
Anaconda Biomed S.L.327 enrolled22 locationsNCT06370182
Recruiting
Not Applicable

Evaluation of the CONDA Stent Retriever in Acute Ischemic Stroke

Acute Ischemic StrokeLarge Vessel Occlusion
Anaconda Biomed S.L.50 enrolled2 locationsNCT07174505
Recruiting

Image Detection of Impaired Microcirculatory Reperfusion

Ischemic Stroke, AcuteLarge Vessel Occlusion
University of Cincinnati40 enrolled1 locationNCT07099599
Recruiting

Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort

Acute Ischemic StrokeLarge Vessel Occlusion
First Affiliated Hospital of Wannan Medical College500 enrolled5 locationsNCT06963489
Recruiting

Acute Ischemic Stroke EndoVascular Therapy: a Multicenter REGISTRY Study

ThrombectomyThrombosisAcute Ischemic Stroke+1 more
Changhai Hospital10,000 enrolled1 locationNCT05864638
Recruiting
Phase 3

Combination of Hypothermia and Thrombectomy in Acute Stroke

Ischemic StrokeLarge Vessel OcclusionEndovascular Treatment
University of Freiburg400 enrolled1 locationNCT06301412
Recruiting

Rescue Stenting and Intravenous Thrombolysis In Patients With Large Vessel Ischemic Stroke

Stroke, AcuteThrombolysisLarge Vessel Occlusion+1 more
ASST Santi Paolo e Carlo400 enrolled7 locationsNCT06727006
Recruiting
Not Applicable

Thrombectomy Versus Best Medical Management in Large Vessel Occlusion Stroke Patients Presenting Beyond 24 Hours and With Presence of Collateral Flow on CT Angiography

ThrombectomyStroke, AcuteMedical Treatment+1 more
Tianjin Huanhu Hospital350 enrolled1 locationNCT06654375
Recruiting

Ischemic Post-conditioning in the Treatment of Acute Ischemic Stroke

Acute Ischemic StrokeLarge Vessel OcclusionIntracranial Artery Occlusion With Cerebral Infarction+1 more
Ming Wei200 enrolled1 locationNCT06456437
Recruiting

Triage of Patients Presenting Beyond 24 Hours With Acute Ischemic Stroke Due to Large Vessel Occlusions (TRACK-LVO Late)

Acute Ischemic StrokeLarge Vessel OcclusionEndovascular Thrombectomy
Tianjin Huanhu Hospital1,000 enrolled1 locationNCT06200753
Recruiting

Triage of Patients With Acute Ischemic Stroke Due to Large Vessel Occlusions-2

Endovascular ProceduresLarge Vessel OcclusionStroke, Acute Ischemic
Tianjin Huanhu Hospital5,000 enrolled4 locationsNCT05659160