RecruitingNCT06963489

Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort

Sponsor

First Affiliated Hospital of Wannan Medical College

Enrollment

500 participants

Start Date

Apr 27, 2025

Study Type

OBSERVATIONAL

Conditions

Acute Ischemic Stroke Large Vessel Occlusion

Summary

This multicenter, ambispective cohort study establishes a comprehensive multiomics biobank from five stroke centers, encompassing thrombi, intracranial blood, peripheral arterial/venous blood, and clinical-laboratory-imaging-follow-up data from patients with acute ischemic stroke with large vessel occlusion (AIS-LVO).

Eligibility

Inclusion Criteria6

Age over 18 years.
Patients with intracranial and extracranial large vessel occlusion ischemic stroke confirmed by cerebrovascular angiography.
Availability of complete clinical and follow-up information required for the study.
Availability of blood and/or thrombus biological samples.
Voluntary written informed consent signed by the patient or their family (1) For retrospectively enrolled patients, a "broad informed consent" was signed at the time of sample collection. Upon enrollment into the cohort, a follow-up phone call was made to confirm the informed consent.
(2) For prospectively enrolled patients, informed consent for this study was signed at the time of enrollment by the patient or their family.