Phase 2 Leg Clinical Trials

17 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 117 of 17 trials

Recruiting
Phase 2Phase 3

A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With Dipyridamole

Restless Leg Syndrome Due to Uraemia
Yunfeng Xia80 enrolled1 locationNCT07199504
Recruiting
Phase 2

MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers

Venous Leg UlcerVenous Stasis Ulcer
Merakris Therapeutics80 enrolled10 locationsNCT04647240
Recruiting
Phase 2

Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

Recurrent Grade 3b Follicular LymphomaRefractory Grade 3b Follicular LymphomaRecurrent Transformed Non-Hodgkin Lymphoma+28 more
Mayo Clinic41 enrolled7 locationsNCT06834373
Recruiting
Phase 2

Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 RearrangementsRefractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 RearrangementsRecurrent Grade 3b Follicular Lymphoma+19 more
David Bond, MD37 enrolled1 locationNCT05821088
Recruiting
Phase 2

A Dose-finding Study of JMKX003142 in Treatment of Renal Edema

Edema SecondaryEdema Leg
Jemincare216 enrolled2 locationsNCT06670534
Recruiting
Phase 1Phase 2

Safety and Preliminary Efficacy of TrophiPatch, an Adipose-Derived Stromal Cell Patch for Chronic Leg Ulcers

Diabetic Foot Ulcer (DFU)Venous Leg Ulcer (VLU)
Nicolò Brembilla18 enrolled1 locationNCT07048054
Recruiting
Phase 2

Evaluate Use of Tropocells(R) Autologous Platelet-rich Fibrin (PRF) for Wagner Grade 1 and Grade 2, Mild to Mod Neuroischemic Plantar Diabetic Foot Ulcer Wound Care.

Type 2 Diabetes Mellitus (T2DM)Type 1 Diabetes MellitusDiabetic Foot Ulcer+3 more
Estar Medical dba Medical Technologies, LTD30 enrolled2 locationsNCT06810726
Recruiting
Phase 1Phase 2

A Study of XSTEM-VLU in Patients With Difficult-to-heal Venous Leg Ulcers

Venous Leg Ulcer
Xintela AB6 enrolled4 locationsNCT05549609
Recruiting
Phase 2

A study testing a gel containing 0.1% mometasone furoate, applied once a day, to see if it helps in the treatment of chronic leg wounds

Chronic leg wounds
Ego Pharmaceuticals20 enrolled1 locationACTRN12624001365550
Recruiting
Phase 1Phase 2

Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)

Spasticity, MuscleSpastic ParaplegiaMicrocephaly+3 more
Elpida Therapeutics SPC4 enrolled1 locationNCT05518188
Recruiting
Phase 2

Oxygen As an Acute Treatment in Alternating Hemiplegia of Childhood

Alternating Hemiplegia of Childhood
Assistance Publique - Hôpitaux de Paris24 enrolled2 locationsNCT06248645
Completed
Phase 2

The Vitamin C after Cardiac Surgery Study

Low blood pressureVasoplegia
Austin Hospital50 enrolled2 locationsACTRN12617000793314
Recruiting
Phase 2

Evaluation of glyceryl trinitrate ointment as treatment for leg ulcers

Chronic venous leg ulcers
The Prince Charles Hospital40 enrolled1 locationACTRN12616000520437
Completed
Phase 2Phase 3

Upper limb - Baby Early Action-observation Training: Randomised trial of the effect of infant action observation training on the early development of hand reaching and grasping in healthy infants and in infants with early brain injury.

Venous infarctionAsymmetric brain lesionsCongenital hemiplegia+1 more
Professor Roslyn Boyd72 enrolled1 locationACTRN12611000991910
Completed
Phase 2

A Pilot Efficacy and Safety Study of IPX159 for the Treament of Restless Legs Syndrome.

Restless Legs Syndrome
IMPAX Pharmaceuticals28 enrolled1 locationACTRN12608000558325
Terminated
Phase 2Phase 3

A phase II/III study to evaluate the efficacy and safety of MD 920 (Gibberellic Acid and Salt 1:1) in patients with hard to heal chronic venous ulceration

venous leg ulcers
AUS BIO Ltd158 enrolled1 locationACTRN12608000060347
Completed
Phase 2Phase 3

Progressive resistant exercise programme for healing venous leg ulcers

Venous leg ulceration
Principal investigator (Andrew Jull)50 enrolled1 locationACTRN12606000491561