LET Clinical Trials

454 recruitingLast updated: May 13, 2026

There are 454 actively recruiting let clinical trials across 65 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3, Early Phase 1. Top locations include Boston, Massachusetts, United States, Beijing, Beijing Municipality, China, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


LET Trials at a Glance

454 actively recruiting trials for let are listed on ClinicalTrialsFinder across 6 cities in 65 countries. The largest study group is Not Applicable with 212 trials, with the heaviest enrollment activity in Boston, Beijing, and Houston. Lead sponsors running let studies include Chinese University of Hong Kong, Beijing Tiantan Hospital, and The University of Sydney.

Treatments under study

About LET Clinical Trials

Looking for clinical trials for LET? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new LET trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about LET clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 454 trials

Recruiting
Phase 1

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency

Inherited Bone Marrow Failure SyndromeFamilial Platelet Disorder With Predisposition to Myeloid Malignancies
National Cancer Institute (NCI)75 enrolled1 locationNCT06090669
Recruiting
Not Applicable

Life-Style Medicine for Chronic Musculoskeletal Pain in Older People

Pain ManagementMusculoskeletal PainChronic Pain+1 more
Chinese University of Hong Kong268 enrolled1 locationNCT07194239
Recruiting
Phase 2Phase 3

A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Bristol-Myers Squibb590 enrolled277 locationsNCT07063745
Recruiting
Not Applicable

ProVu Video Stylet With Versus Without the Fekry Airway

Endotracheal IntubationVideo Rigid Stylet
Cairo University130 enrolled2 locationsNCT07568743
Recruiting

Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair

Platelet ActivationThoraco-abdominal Aortic Aneurysm RepairCoagulation Factors Alterations
University of Thessaly58 enrolled2 locationsNCT06432387
Recruiting
Early Phase 1

Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms

Breast CancerAromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)Joint Pain
Philip Chang30 enrolled2 locationsNCT06123286
Recruiting
Not Applicable

AI-Assisted Camera-Based Progressive Muscle Relaxation for Office Workers

work-related musculoskeletal disordersMusculoskeletal PainStress, Physiological+1 more
Istanbul Medipol University Hospital60 enrolled1 locationNCT07571967
Recruiting
Not Applicable

Effectiveness of Communication-Focused Pain Neuroscience Education in Chronic Musculoskeletal Pain

Chronic Musculoskeletal Pain
University of Thessaly90 enrolled1 locationNCT07001449
Recruiting

100-Year Human Aging Study

Disability PhysicalNeoplasmsCardiovascular Diseases+12 more
Longevity Metrics, Inc.10,000 enrolled1 locationNCT07563777
Recruiting

Natural History of Inflammatory Muscle Diseases

Inflammation In Skeletal Muscle
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)500 enrolled1 locationNCT05738824
Recruiting
Not Applicable

Thulium Laser Enucleation With Bladder Neck Incision for Small-Volume Benign Prostatic Hyperplasia

Benign Prostatic HyperplasiaLower Urinary Tract Symptoms (LUTS)Bladder Outlet Obstruction
Chinese PLA General Hospital426 enrolled1 locationNCT07569874
Recruiting

The RheumSafer Study: Improving Medication Appropriateness in People With Rheumatic Conditions

VasculitisSystemic Lupus Erthematosus (SLE)Rheumatic Diseases+3 more
McGill University Health Centre/Research Institute of the McGill University Health Centre100 enrolled1 locationNCT07278609
Recruiting

Exercise, Pain Beliefs, and Activity Patterns in Musculoskeletal Pain

Activity LevelMusculoskeletal Pain - Acute and Subacute ConditionsExercise (EX)+1 more
Istinye University55 enrolled1 locationNCT07528807
Recruiting
Not Applicable

Mindfulness-based Rehabilitation in a University Museum Setting to Reduce Pain and Improve Quality of Life in Women With Fibromyalgia: a Randomized Controlled Trial

Musculoskeletal PainChronic PainFibromyalgia
G. d'Annunzio University44 enrolled2 locationsNCT07048366
Recruiting

Observational Multicenter Study in Patients Receiving Chemotherapy and Amivantamab for Metastatic Non-small Cell Lung Cancer

Non-small Cell Lung Cancer (NSCLC)Non-small Cell Lung CancerNSCLC+6 more
GFPC Investigation100 enrolled16 locationsNCT07563205
Recruiting
Phase 1

A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors

Advanced or Metastatic Solid Tumors With Homozygous MTAP Deletion
Shouyao Holdings (Beijing) Co. LTD122 enrolled1 locationNCT07469982
Recruiting
Not Applicable

Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.

Malignant Gastric Outlet Obstruction
AdventHealth70 enrolled1 locationNCT06128018
Recruiting
Not Applicable

A Pilot Study to Evaluate the Ability of Lactoferrin to Modulate Iron Homeostasis and Exercise Performance in Exercising Females

Low ferritinIron DeficienciesIron-deficiency+1 more
Lindenwood University30 enrolled1 locationNCT07546591
Recruiting
Not Applicable

Osteopathic Manipulative Treatment vs Physiotherapy in Cervicocranial Dysfunction

Cervicogenic headacheDizzinessNeck Pain Musculoskeletal+1 more
Burim Peli50 enrolled1 locationNCT07555873
Recruiting

Lynch Syndrome X-Talk of Enteral Mucosa With Immune System

Hereditary Cancer SyndromeHereditary CancerLynch Syndrome+19 more
San Raffaele University300 enrolled5 locationsNCT06708429