LET Clinical Trials

506 recruitingLast updated: July 25, 2026

There are 506 actively recruiting let clinical trials across 66 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 4, Phase 3, Early Phase 1. Top locations include Boston, Massachusetts, United States, Beijing, Beijing Municipality, China, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


LET Trials at a Glance

506 actively recruiting trials for let are listed on ClinicalTrialsFinder across 6 cities in 66 countries. The largest study group is Not Applicable with 244 trials, with the heaviest enrollment activity in Boston, Beijing, and Houston. Lead sponsors running let studies include Chinese University of Hong Kong, Beijing Tiantan Hospital, and Cairo University.

Treatments under study

About LET Clinical Trials

Looking for clinical trials for LET? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new LET trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about LET clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 506 trials

Recruiting

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

SYNGAP1-Related Intellectual DisabilityDLG4FOXP1+184 more
Simons Searchlight100,000 enrolled2 locationsNCT01238250
Recruiting
Not Applicable

Assessing Tissue Response to High-Velocity Thrust Manipulations on Capsule Length and Stiffness at the C5-C6 Facet Joint Capsule

Neck Pain Musculoskeletal
Florida Gulf Coast University40 enrolled1 locationNCT07704853
Recruiting
Phase 4

SGLT2i Therapy in Islet Transplantation (SIT)

DiabetesPartial Islet FunctionTPIAT
University of Minnesota40 enrolled1 locationNCT07228195
Recruiting
Not Applicable

Prebiotic Inulin for Late-Reproductive Individuals

Insulin ResistanceObesity, OverweightMicrobiota+9 more
George Washington University27 enrolled1 locationNCT07724522
Recruiting

Artificial Intelligence-Assisted Advanced Analysis of Knee Imaging and Outcome Prediction

Artificial IntelligenceKnee OsteoarthritisDegenerative Knee Disorders+1 more
National Taiwan University Hospital310 enrolled1 locationNCT07721116
Recruiting
Phase 1

Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency

Inherited Bone Marrow Failure SyndromeFamilial Platelet Disorder With Predisposition to Myeloid Malignancies
National Cancer Institute (NCI)75 enrolled1 locationNCT06090669
Recruiting
Phase 2Phase 3

A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Bristol-Myers Squibb590 enrolled318 locationsNCT07063745
Recruiting

Efficacy and Safety of Intravenous Thrombolysis in Branch Atheromatous Disease

StrokeAcute Ischemic StrokeThrombolysis+2 more
Sigmund Freud PrivatUniversitat462 enrolled8 locationsNCT07299994
Recruiting
Not Applicable

Nordic vs Blood Flow Restriction Nordic Exercise in Elite Female Pole Vaulters

Sports injury preventionAthletic PerformanceMuscle Strength+1 more
Toros University36 enrolled1 locationNCT07705698
Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

ThrombophiliaThrombosisSickle Cell Disease+10 more
American Thrombosis and Hemostasis Network3,000 enrolled71 locationsNCT04398628
Recruiting
Not Applicable

Evaluation of Biomechanical Forced During the Practice of Endoscopic Retrograde Cholangiopancreatography

Musculoskeletal DisordersERCPBiomechanic
Centre Hospitalier Universitaire, Amiens10 enrolled1 locationNCT07691580
Recruiting
Not Applicable

Clinical Performance and Quality of Life of 3D-Printed Complete Dentures Under Digital vs Hybrid Workflows: A Randomized Crossover Trial

Complete Edentulism
Universidad de Especialidades Espiritu Santo20 enrolled1 locationNCT07626827
Recruiting
Phase 2

METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)

Endocrine System DiseasesImmune System DiseasesAutoimmune Diseases+6 more
University of Washington60 enrolled2 locationsNCT07699380
Recruiting
Not Applicable

Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity

ObesitySkeletal MuscleBrain Connectivity
Washington University School of Medicine40 enrolled1 locationNCT07091500
Recruiting
Not Applicable

THeragnostic Utilities for Neoplastic DisEases of the Rectum by MRI Guided Radiotherapy

Pathological Complete ResponseLocally Advanced Rectal CancerNeoadjuvant Chemoradiotherapy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS179 enrolled1 locationNCT04815694
Recruiting
Not Applicable

Core Stability vs Scapular Stabilization on Hand Grip Strength in Chronic Myofascial Neck Pain

Hand Grip StrengthNeck Pain MusculoskeletalTrigger Point in Trapezius Muscle+5 more
Cairo University60 enrolled1 locationNCT07692126
Recruiting

China Research for Severe Spontaneous Intracerebral Hemorrhage(CRISIH)

Emergency surgeryComplicationsDisorders of Consciousness+2 more
Beijing Tiantan Hospital2,000 enrolled1 locationNCT05975398
Recruiting
Not Applicable

Effectiveness of Virtual Bodily Illusion Intervention in Upper Limb Motor Function in People With Incomplete Spinal Cord Injury.

Incomplete Spinal Cord InjurySpinal Cord Injury
University of Valencia80 enrolled1 locationNCT05142943
Recruiting
Not Applicable

Jaw Tracking Impact on Occlusion and Patient Outcomes in Maxillary Implant Restorations

Complete maxillary edentulismEdentulism
Mansoura University20 enrolled1 locationNCT07693946
Recruiting
Phase 1Phase 2

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

AngiosarcomaLiposarcomaAdipocytic Neoplasm+6 more
St. Jude Children's Research Hospital139 enrolled7 locationsNCT06239272