LET Clinical Trials in Boston, Massachusetts

20 recruitingBoston, Massachusetts

Showing 120 of 20 trials

Recruiting
Phase 2Phase 3

A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Bristol-Myers Squibb590 enrolled277 locationsNCT07063745
Recruiting
Not Applicable

Pain Disengagement Training (Open Pilot)

Chronic Musculoskeletal Pain
Massachusetts General Hospital10 enrolled1 locationNCT06870162
Recruiting
Phase 1Phase 2

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

AngiosarcomaLiposarcomaAdipocytic Neoplasm+6 more
St. Jude Children's Research Hospital139 enrolled6 locationsNCT06239272
Recruiting
Phase 1Phase 2

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

Lung CancerNSCLCThoracic Cancer+5 more
Tango Therapeutics, Inc.183 enrolled18 locationsNCT06922591
Recruiting
Phase 1Phase 2

A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors

MTAP-deleted Solid Tumors
Bayer370 enrolled60 locationsNCT06914128
Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Hodgkin LymphomaNon-Hodgkin LymphomaHematologic Malignancies+14 more
Center for International Blood and Marrow Transplant Research99,999 enrolled142 locationsNCT01351545
Recruiting
Phase 1Phase 2

S095035 as a Single Agent and in Combination in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of MTAP

MTAP-deleted Solid Tumors
Servier Bio-Innovation LLC342 enrolled35 locationsNCT06188702
Recruiting
Not Applicable

Neonatal Platelet Transfusion Threshold Trial

ThrombosisThrombocytopeniaNeonatal+4 more
NICHD Neonatal Research Network2,433 enrolled20 locationsNCT06676904
Recruiting
Phase 3

SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

GliomaAstrocytoma, IDH-Mutant, Grade 2Astrocytoma, Grade IV+5 more
Nuvation Bio Inc.365 enrolled45 locationsNCT05303519
Recruiting

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Mitochondrial DiseasesMitochondrial DisordersMitochondrial Genetic Disorders+2 more
Columbia University1,000 enrolled17 locationsNCT01694940
Recruiting
Not Applicable

The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain

COPDChronic Musculoskeletal Pain
VA Office of Research and Development136 enrolled1 locationNCT05701982
Recruiting
Not Applicable

Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients

PainOpioidPilot Study+1 more
Massachusetts General Hospital100 enrolled1 locationNCT07265557
Recruiting

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

ThrombophiliaThrombosisSickle Cell Disease+10 more
American Thrombosis and Hemostasis Network3,000 enrolled71 locationsNCT04398628
Recruiting
Not Applicable

OnTrackCF: Engagement, Feasibility, and Acceptability Study

Cystic Fibrosis (CF)Cystic Fibrosis - Complete
Boston Children's Hospital60 enrolled3 locationsNCT07031323
Recruiting
Not Applicable

Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain

Musculoskeletal PainChronic Pain
Brigham and Women's Hospital10 enrolled1 locationNCT06632535
Recruiting
Not Applicable

Improving Health for Older Adults With Pain Through Engagement

Musculoskeletal PainChronic Pain
Massachusetts General Hospital200 enrolled1 locationNCT06119698
Recruiting

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

SYNGAP1-Related Intellectual DisabilityDLG4FOXP1+181 more
Simons Searchlight100,000 enrolled2 locationsNCT01238250
Recruiting

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

Heart FailureCardiogenic ShockMuscle Atrophy+1 more
Tufts Medical Center60 enrolled1 locationNCT06253104
Recruiting

Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block

Heart Block CompleteHeart Block Second Degree
The Hospital for Sick Children350 enrolled27 locationsNCT04559425
Recruiting
Phase 1

The HALT Biomarker Study

Aortic StenosisHypo-attenuated Leaflet ThickeningBioprosthetic Valve Degeneration
Massachusetts General Hospital300 enrolled3 locationsNCT04552275