Liver Clinical Trials

1,075 recruitingLast updated: June 17, 2026

There are 1,075 actively recruiting liver clinical trials across 72 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, Houston, Texas, United States, Philadelphia, Pennsylvania, United States. Updated daily from ClinicalTrials.gov.


Liver Trials at a Glance

1,075 actively recruiting trials for liver are listed on ClinicalTrialsFinder across 6 cities in 72 countries. The largest study group is Not Applicable with 350 trials, with the heaviest enrollment activity in New York, Houston, and Philadelphia. Lead sponsors running liver studies include IRCCS Azienda Ospedaliero-Universitaria di Bologna, Institute of Liver and Biliary Sciences, India, and Assistance Publique - Hôpitaux de Paris.

Treatments under study

About Liver Clinical Trials

Looking for clinical trials for Liver? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,075 trials

Recruiting
Phase 1Phase 2

Safety of HRX215 in Patients After Minor and Major Liver Resection

Liver ResectionColorectal Carcinoma Liver Metastases
HepaRegeniX GmbH80 enrolled6 locationsNCT06638502
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Not Applicable

Screening in Primary Care of Advanced Liver Fibrosis in NAFLD and/or Alcoholic Patients

Liver FibrosisNon-alcoholic Fatty Liver Disease NAFLDAlcoholic Liver Disease (ALD)
University Hospital, Angers1,788 enrolled13 locationsNCT05699018
Recruiting
Not Applicable

Rectus-Intercostal Fascial Plane Block for Liver Transplantation Donors

Postoperative PainLiver TransplantationLiving Donor
Istinye University64 enrolled1 locationNCT07233096
Recruiting
Phase 1

A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment

Liver DiseasesHepatic Insufficiency
Incyte Corporation16 enrolled4 locationsNCT07559474
Recruiting

Prediction Model for MINS After Major Hepatobiliary Surgery

Postoperative ComplicationsLiver NeoplasmMyocardial Injury After Noncardiac Surgery (MINS)+1 more
Beijing Tsinghua Chang Gung Hospital1,800 enrolled6 locationsNCT07335042
Recruiting

The Mycophenolate Pregnancy Registry

Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases
Genentech, Inc.500 enrolled1 locationNCT01733082
Recruiting
Not Applicable

UNMASK: UNveiling the Pathobiology of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) for the Discovery of Novel Therapeutics and biomarKers

MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla450 enrolled3 locationsNCT07652151
Recruiting
Not Applicable

The Vanguard Study: Testing a New Way to Screen for Cancer

Breast CarcinomaOvarian CarcinomaBladder Carcinoma+8 more
National Cancer Institute (NCI)24,000 enrolled37 locationsNCT06995898
Recruiting
Not Applicable

Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill Patients

Feasibility, Tolerance and Safety of VR Delivery in an Adult ICU
Milton S. Hershey Medical Center30 enrolled1 locationNCT07649876
Recruiting

Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals

Non-Alcoholic Fatty Liver DiseaseLow Birth Weight
Steno Diabetes Center Copenhagen300 enrolled1 locationNCT05890365
Recruiting
Not Applicable

OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases

Liver MetastasesStereotactic Body Radiation TherapyMRI-guided Treatment
University of Wisconsin, Madison32 enrolled1 locationNCT04020276
Recruiting
Phase 3

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Metabolic dysfunction-associated steatohepatitis (MASH)Liver Fibrosis
Boehringer Ingelheim1,800 enrolled526 locationsNCT06632444
Recruiting
Not Applicable

Early General Anesthesia to Limit Experiences of Trauma During Cesarean Section-Pilot Study

Cesarean SectionDelivery; Trauma
University of Pennsylvania600 enrolled1 locationNCT07334418
Recruiting
Phase 2

A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

Liver Cirrhosis
Boehringer Ingelheim29 enrolled27 locationsNCT07325526
Recruiting
Not Applicable

ProspEXPO : Study of the Associations Between Hepatocellular Carcinoma and Chemical and Psychosocial Environmental EXPOsome

Cirrhoses, LiverCarcinoma Liver
University Hospital, Angers300 enrolled4 locationsNCT07119957
Recruiting
Not Applicable

Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease

MASLDFatty Liver
Henry Ford Health System125 enrolled1 locationNCT07646197
Recruiting
Phase 2

Y-90 Treatment Response Using Transarterial Radioembolization

Liver CancerHepatocellular CarcinomaPrimary Liver Cancer+3 more
Thomas Jefferson University30 enrolled1 locationNCT07145801
Recruiting

mSEPT9 Biomarker for Predicting Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis

CirrhosisHepatocellular Carcinoma (HCC)Epigenomics+1 more
Central Hospital, Nancy, France400 enrolled1 locationNCT06778317
Recruiting
Not Applicable

Erector Spinae Plane Block Versus Thoracic Epidural Analgesia for Open Liver Resection

Liver CancerLiver NeoplasmsHepatic Resection
Nguyen Toan Thang60 enrolled1 locationNCT07642336