Liver Clinical Trials

5 recruiting

Frequently Asked Questions

Common questions about Liver clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 874 trials

Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Not Applicable

Siemens Biomarker Multi-modality

Fatty LiverHepatic Steatosis
Duke University45 enrolled1 locationNCT07495332
Recruiting
Not Applicable

The Vanguard Study: Testing a New Way to Screen for Cancer

Breast CarcinomaOvarian CarcinomaBladder Carcinoma+8 more
National Cancer Institute (NCI)24,000 enrolled36 locationsNCT06995898
Recruiting
Phase 2

At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer

Advanced Colorectal CarcinomaAdvanced Anal CarcinomaAdvanced Biliary Tract Carcinoma+40 more
Mayo Clinic220 enrolled2 locationsNCT05969860
Recruiting
Phase 2

A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

Liver Cirrhosis
Boehringer Ingelheim30 enrolled21 locationsNCT07325526
Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

CholangiocarcinomaHepatocellular CarcinomaHepatic Carcinoma+4 more
City of Hope Medical Center400 enrolled5 locationsNCT06342414
Recruiting
Phase 2

A Trial to Evaluate Efficacy and Safety of Maridebart Cafraglutide in Adults Living With Elevated Liver Fat and Obesity or Overweight

Overweight or Obesity and Elevated Liver Fat
Amgen180 enrolled10 locationsNCT07441252
Recruiting

Collection of Blood From Patients With Cancer

Breast CancerLiver CancerProstate Cancer+2 more
National Cancer Institute (NCI)1,750 enrolled1 locationNCT00034216
Recruiting

DESTINY-PANTUMOUR04

Liver CancerEsophageal CancerPancreatic Cancer+24 more
AstraZeneca100 enrolled15 locationsNCT07124000
Recruiting

Evaluation of Patients With Liver Disease

Hepatitis BHepatitis CLiver Disease+1 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)8,050 enrolled1 locationNCT00001971
Recruiting

Early Tracking of Childhood Health Determinants (ETCHED) Study

Diabetes MellitusObesityFatty Liver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,500 enrolled1 locationNCT03481829
Recruiting
Phase 2

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)416 enrolled18 locationsNCT06075745
Recruiting

Perioperative Hemostasis Management in Liver Transplantation

Liver Transplant; Complications
Société Française d'Anesthésie et de Réanimation1,200 enrolled16 locationsNCT06257407
Recruiting
Phase 3

Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

Turner SyndromeIdiopathic Short StatureShort Stature Homeobox Gene Mutation+1 more
Ascendis Pharma A/S186 enrolled5 locationsNCT07221851
Recruiting
Phase 2

A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver Disease

Liver Diseases, Alcoholic
GlaxoSmithKline393 enrolled131 locationsNCT06613698
Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Liver NeoplasmsPrimary Liver CancerSecondary Liver Cancer+2 more
HistoSonics, Inc.5,000 enrolled27 locationsNCT06486454
Recruiting
Not Applicable

TheraSphere Japan Pre-Market Study

Liver Neoplasms
Boston Scientific Corporation51 enrolled4 locationsNCT07377487
Recruiting
Phase 2

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Liver MetastasesColorectal Cancer Metastatic
Weill Medical College of Cornell University24 enrolled1 locationNCT06300463
Recruiting
Phase 1Phase 2

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Advanced Liver Cancers
Hoffmann-La Roche518 enrolled33 locationsNCT04524871
Recruiting
Phase 1Phase 2

Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC

Metastatic Liver CancerAdvanced Hepatocellular Carcinoma (HCC)
Beijing Biotech30 enrolled1 locationNCT07500220