Cirrhosis Clinical Trials

87 recruiting

Cirrhosis Trials at a Glance

226 actively recruiting trials for cirrhosis are listed on ClinicalTrialsFinder across 6 cities in 44 countries. The largest study group is Not Applicable with 75 trials, with the heaviest enrollment activity in Cleveland, London, and Dallas. Lead sponsors running cirrhosis studies include Assistance Publique - Hôpitaux de Paris, Institute of Liver and Biliary Sciences, India, and Northern Jiangsu People's Hospital.

Browse cirrhosis trials by phase

Treatments under study

About Cirrhosis Clinical Trials

Looking for clinical trials for Cirrhosis? There are currently 87 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cirrhosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cirrhosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 226 trials

Recruiting
Phase 2

A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

Liver Cirrhosis
Boehringer Ingelheim30 enrolled27 locationsNCT07325526
Recruiting
Not Applicable

Early TIPS in Patients With Liver Cirrhosis and Ascites

Liver CirrhosisPortal HypertensionAscites Hepatic
University Hospital Freiburg134 enrolled1 locationNCT06576934
Recruiting

Muscle Mass Via UltraSound in Cirrhosis (MMUSCLE)

SarcopeniaCirrhosisMalnutrition
University Hospital, Antwerp60 enrolled1 locationNCT06345547
Recruiting

Freiburg TIPS Registry

Liver CirrhosisPortal Vein ThrombosisPortal Hypertension+3 more
University Hospital Freiburg2,000 enrolled1 locationNCT05782556
Recruiting
Phase 1

The Phase 1, Open-label, PET Trial Designed to Investigate the Effect of AZD2389 on FAP Occupancy in the Liver in Participants With Advanced Liver Fibrosis.

Hepatic CirrhosisLiver Fibrosis
AstraZeneca12 enrolled2 locationsNCT07069725
Recruiting
Not Applicable

PSYLIVER-PILOTE: Involvement of the Autonomic Nervous System in Hepatocellular Carcinoma (HCC)

CirrhosisHepato Cellular Carcinoma
Hospices Civils de Lyon100 enrolled1 locationNCT07393074
Recruiting
Not Applicable

A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients

SurgeryObesityCirrhosis+1 more
University Hospital, Lille100 enrolled1 locationNCT03472157
Recruiting

Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Placement

Liver CirrhosisPortal Hypertension
Assistance Publique - Hôpitaux de Paris45 enrolled1 locationNCT07439939
Recruiting
Not Applicable

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Carcinoma, HepatocellularCirrhosis
VA Office of Research and Development4,700 enrolled32 locationsNCT05486572
Recruiting
Not Applicable

Online Prehabilitation for Patients Awaiting Liver Transplantation

Liver Transplant SurgeryCirrhosis, LiverLiver Disease
University of Alberta177 enrolled6 locationsNCT05899231
Recruiting

Development of 4D Flow MRI for Risk Stratification of Variceal Bleeding in Cirrhosis

Cirrhosis, LiverGastroesophageal VaricesFontan Procedure
University of Wisconsin, Madison146 enrolled1 locationNCT04867954
Recruiting
Not Applicable

Microbiome Modulation With Prebiotics in PTSD and Cirrhosis

CirrhosisPTSD
Hunter Holmes Mcguire Veteran Affairs Medical Center30 enrolled1 locationNCT06464952
Recruiting
Phase 4

Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis

CirrhosisAscitesPortal Vein Thrombosis+3 more
Asian Institute Of Medical Sciences220 enrolled1 locationNCT07521332
Recruiting
Phase 2

Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement

CirrhosisHepatic Encephalopathy
Hunter Holmes Mcguire Veteran Affairs Medical Center30 enrolled1 locationNCT06052176
Recruiting
Phase 3

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis
89bio, Inc.762 enrolled291 locationsNCT06419374
Recruiting
Not Applicable

CirrhosisRx CDS System

CirrhosisDecision Support Systems, Clinical
University of California, San Francisco2,106 enrolled1 locationNCT05967273
Recruiting
Not Applicable

Vagus Nerve-guided Laparoscopic Splenectomy and Azygoportal Disconnection

CirrhosisHypertension, PortalHypersplenism
Northern Jiangsu People's Hospital15 enrolled2 locationsNCT07462091
Recruiting
Phase 2

SAMe Trial for Patients With Alcoholic Cirrhosis

Alcoholic Cirrhosis
Indiana University196 enrolled2 locationsNCT04250259
Recruiting
Not Applicable

Efficacy of Apixaban in Treating Portal Vein Thrombosis Occurring More Than One Year After LSD

CirrhosisPortal Vein ThrombosisHypertension, Portal+1 more
Northern Jiangsu People's Hospital20 enrolled1 locationNCT07461532
Recruiting
Not Applicable

Efficacy of Apixaban in the Treatment of Portal Vein Thrombosis Occurring More Than One Year After LS

CirrhosisPortal Vein ThrombosisHypertension, Portal+1 more
Northern Jiangsu People's Hospital20 enrolled1 locationNCT07461545