Phase 4 Local Clinical Trials
16 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–16 of 16 trials
Recruiting
Phase 4
Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance
Stage III Prostate Cancer AJCC v8Localized Prostate CarcinomaStage I Prostate Cancer AJCC v8+1 more
Roswell Park Cancer Institute600 enrolled1 locationNCT06733350
Recruiting
Phase 4
Study Aiming to Compare the Plasma Exposure of the Payload (Free-DXd) in Patients Treated by T-DXd for Locally Advanced or Metastatic Breast Cancer According to Their BMI.
Locally Advanced or Metastatic Breast Cancers
Institut Claudius Regaud210 enrolled11 locationsNCT07195344
Recruiting
Phase 4
Pain Relief Following Laparoscopic Cholecystectomy While Comparing Intra Abdominal Versus Sub Cutaneous Local Anesthetic Administration
Laparoscopic Cholecystectomy SurgeryAnalgeisaLocal Anesthetic Infiltration
Rawalpindi Medical College100 enrolled1 locationNCT07409688
Recruiting
Phase 4
Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial
Metastatic Bladder Urothelial CarcinomaStage IV Bladder Cancer AJCC v8Metastatic Renal Pelvis and Ureter Urothelial Carcinoma+4 more
Mayo Clinic75 enrolled1 locationNCT06764095
Recruiting
Phase 4
Split Face Study of the Duration of Local Anesthetics - Fourth Arm
Anesthesia, Local
Weill Medical College of Cornell University35 enrolled1 locationNCT06694714
Recruiting
Phase 4
Digital Monitoring of Self-reported Symptoms by Patients Treated With Cabozantinib Plus Nivolumab for Advanced Clear-cell Renal Carcinoma
Metastatic Renal Cell CarcinomaLocally AdvancedRenal Cell Carcinoma (Kidney Cancer)
Centre Francois Baclesse83 enrolled10 locationsNCT07028125
Recruiting
Phase 4
A Study of Bupivacaine Liposome Injection in Local Analgesia of Pediatric Patients
Local Analgesia Via Infiltration
Jiangsu HengRui Medicine Co., Ltd.232 enrolled1 locationNCT06344091
Recruiting
Phase 4
Investigating the Effect of Pericapsular Nerve Group (PENG) Block on Postoperative Pain After Peri-acetabular Osteotomy
Anesthesia, Local
Matias Vested90 enrolled1 locationNCT06406010
Recruiting
Phase 4
Safety and Efficacy of Pembrolizumab in Combination with Bevacizumab + CapeOX in the Neoadjuvant Treatment of RAS-mutated, BRAF Wild-type, Microsatellite-stabilized, Locally Advanced Colorectal Cancer
Locally Advanced Colorectal Cancer
yangjianjun20 enrolled1 locationNCT06550453
Recruiting
Phase 4
Select the Appropriate Population for Adding CDK4/6i to Neoadjuvant Endocrine Therapy
Locally Advanced Breast CancerHormone Receptor Positive，HER2-negative Breast Cancer
Yongsheng Wang100 enrolled1 locationNCT05809024
Recruiting
Phase 4
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
AnesthesiaAnesthesia, LocalHepatic Resection+1 more
University of California, San Diego70 enrolled1 locationNCT04849455
Completed
Phase 4
Does infiltration of local anaesthesia improve recovery after anterior hip replacement?
total hip replacementlocal infiltration analgesia
Dr Nicole Tan160 enrolled1 locationACTRN12615000844549
Completed
Phase 3Phase 4
Efficacy of the Apitherapy in the treatment of recalcitrant localized plaque psoriasis and evaluation of Tumor Necrosis Factor-Alpha (TNF-a) serum level: Double blind randomized clinical trial.
Localized psoriasis
Faculty of Medicine, Suez Canal University, prof. Atef Elakhras50 enrolled1 locationACTRN12613001028796
Recruiting
Phase 4
Total and free serum Ropivacaine Concentrations for patients receiving Continuous Transversus Abdominis plane block for Postoperative analgesia after abdominal surgery: Pilot Study
Local anaestetic concentration after a bolus followed by continuous infusion in TAP block
Dr Sarika Kumar15 enrolled1 locationACTRN12612000104853
Withdrawn
Phase 4
Effectiveness of dental local analgesia among children for dental extractions
dental local analgesia
Dental Health Services Western Australia50 enrolled1 locationACTRN12610000889055
Terminated
Phase 4
effectiveness of local dental anaesthetic in children
dental local analgesia
Dental Health Services, Western Australia150 enrolled1 locationACTRN12610000873022