Localized Prostate Carcinoma Clinical Trials

17 recruiting

Localized Prostate Carcinoma Trials at a Glance

17 actively recruiting trials for localized prostate carcinoma are listed on ClinicalTrialsFinder across 6 cities in 7 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Jacksonville, San Francisco, and Duarte. Lead sponsors running localized prostate carcinoma studies include Mayo Clinic, City of Hope Medical Center, and CHU de Quebec-Universite Laval.

Browse localized prostate carcinoma trials by phase

Treatments under study

About Localized Prostate Carcinoma Clinical Trials

Looking for clinical trials for Localized Prostate Carcinoma? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Localized Prostate Carcinoma trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Localized Prostate Carcinoma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Early Phase 1

Pilot Study of (MR) Imaging With Pyruvate (13C) to Detect High Grade Prostate Cancer

Prostate CancerLocalized Prostate Carcinoma
Ivan de Kouchkovsky, MD80 enrolled1 locationNCT02526368
Recruiting
Not Applicable

Accuracy of 18F-rhPSMA-7.3 PET/ MRI for Prediction of Lymph Node Metastasis in Localized High-Risk Prostate Cancer

Stage III Prostate Cancer AJCC v8Localized Prostate CarcinomaStage I Prostate Cancer AJCC v8+3 more
Mayo Clinic50 enrolled1 locationNCT06389786
Recruiting
Phase 1

Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617

Prostate CancerLocalized Prostate CarcinomaHigh-risk Prostate Cancer+2 more
Thomas Hope45 enrolled1 locationNCT07054346
Recruiting
Early Phase 1

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

Metastatic Prostate CarcinomaStage IV Prostate Cancer AJCC v8Localized Prostate Carcinoma+1 more
Mayo Clinic220 enrolled2 locationsNCT05045066
Recruiting

Online Adaptive Stereotactic Body Radiotherapy for Localized Prostate Cancer (X-SMILE)

Prostate Cancer (Adenocarcinoma)Localized Prostate CarcinomaProstate Hyperplasia+1 more
University of Zurich75 enrolled3 locationsNCT06834152
Recruiting

Multi-omic Approach to Study HDR Brachytherapy for Favorable Risk and Low Tier Intermediate Risk Prostate Cancer

Localized Prostate Carcinoma
British Columbia Cancer Agency100 enrolled1 locationNCT06200974
Recruiting
Not Applicable

Addressing Health Literacy With a Tailored Survivorship Care Plan

Stage IVB Prostate Cancer AJCC v8Localized Prostate CarcinomaOligometastatic Prostate Carcinoma
Emory University150 enrolled3 locationsNCT06674863
Recruiting
Not Applicable

Golf Recreational Exercise for Enhanced Survivorship in Prostate Cancer Survivors

Locally Advanced Prostate CarcinomaStage III Prostate Cancer AJCC v8Localized Prostate Carcinoma+2 more
University of Southern California20 enrolled2 locationsNCT06500169
Recruiting
Not Applicable

Feasibility and Effect of Wrapping Nerves With a Multi-Layer Perinatal Tissue Allograft During Prostatectomy

Stage III Prostate Cancer AJCC v8Localized Prostate CarcinomaStage I Prostate Cancer AJCC v8+1 more
Mayo Clinic25 enrolled1 locationNCT06940271
Recruiting
Not Applicable

Ultra Hypofractionnated Radiotherapy With HDR Brachytherapy Boost.

Radiotherapy Side EffectProstate CancerRadiotherapy+3 more
CHU de Quebec-Universite Laval205 enrolled1 locationNCT05786742
Recruiting
Phase 2

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

Malignant Solid NeoplasmLocally Advanced Cervical CarcinomaRecurrent Prostate Carcinoma+15 more
City of Hope Medical Center60 enrolled1 locationNCT05722288
Recruiting
Phase 2

PSMA-Guided Ablation of the Prostate

Prostate CancerLocalized Prostate Carcinoma
University of Alberta138 enrolled3 locationsNCT06003556
Recruiting
Not Applicable

24 Gy in One Fraction Urethral-sparing "HDR Like" SBRT for Prostate Cancer

Localized Prostate Carcinoma
IRCCS San Raffaele70 enrolled1 locationNCT05936736
Recruiting
Not Applicable

Two-fraction HDR Monotherapy for Localized Prostate Cancer

Prostate AdenocarcinomaLocalized Prostate Carcinoma
University of California, San Francisco17 enrolled1 locationNCT05665738
Recruiting
Not Applicable

Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer

Localized Prostate CarcinomaStage I Prostate Cancer AJCC v8Stage II Prostate Cancer AJCC v8+2 more
Marc Dall'Era, MD100 enrolled1 locationNCT06178354
Recruiting
Not Applicable

Extraperitoneal SINgle-port rObotic-assisted Radical Prostatectomy (RARP) Versus Transperitoneal Multi-port RARP in the Treatment Of Prostate Cancer (SINO-TOP)

Prostate AdenocarcinomaLocalized Prostate Carcinoma
Shanghai Changzheng Hospital480 enrolled1 locationNCT06238713
Recruiting
Not Applicable

Two-Fraction Ultrahypofractionated Radiotherapy With Focal Boost for Intermediate Risk, Localized Prostate Cancer

Prostate CancerProstate AdenocarcinomaLocalized Prostate Carcinoma
UMC Utrecht160 enrolled1 locationNCT06518226