Phase 1 Locally Advanced Head and Neck Squamous Cell Carcinoma Clinical Trials

3 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–3 of 3 trials

Recruiting

Phase 1

Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer

Locally Advanced Head and Neck Squamous Cell CarcinomaClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Stage III Hypopharyngeal Carcinoma AJCC v8+23 more

National Cancer Institute (NCI)46 enrolled18 locationsNCT05172245

Recruiting

Phase 1Phase 2

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more

Mayo Clinic132 enrolled1 locationNCT05269381

Recruiting

Phase 1Phase 2

De-escalation Radiation Strategy After NAC in Combination With ICI in LAHNSCC

Locally Advanced Head and Neck Squamous Cell Carcinoma

Ruijin Hospital20 enrolled1 locationNCT06572514