Phase 2 Locally Advanced Head and Neck Squamous Cell Carcinoma Clinical Trials

7 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 17 of 7 trials

Recruiting
Phase 2

Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck

Locally Advanced Head and Neck Squamous Cell Carcinoma
Groupe Oncologie Radiotherapie Tete et Cou106 enrolled1 locationNCT06959108
Recruiting
Phase 1Phase 2

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+97 more
Mayo Clinic132 enrolled1 locationNCT05269381
Recruiting
Phase 2

Low-Dose Radiotherapy and Anti-PD-1 Immunotherapy as Neoadjuvant Treatment for Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

Locally Advanced Head and Neck Squamous Cell Carcinoma
Xiwei XU22 enrolled1 locationNCT07371234
Recruiting
Phase 2

Tirilizumab with Albumin-bound Paclitaxel and Cisplatin for Locally Advanced Resectable Oral Squamous Cell Carcinoma

Locally Advanced Head and Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University116 enrolled1 locationNCT06470217
Recruiting
Phase 1Phase 2

De-escalation Radiation Strategy After NAC in Combination With ICI in LAHNSCC

Locally Advanced Head and Neck Squamous Cell Carcinoma
Ruijin Hospital20 enrolled1 locationNCT06572514
Recruiting
Phase 2

A Prospective Randomized Controlled Study of Immune Checkpoint Maintenance Therapy After Radiotherapy and Chemotherapy for Locally Advanced Head and Neck Tumors Based on Peripheral Blood CD8Tex Detection in Peripheral Blood

Locally Advanced Head and Neck Squamous Cell Carcinoma
Second Affiliated Hospital, School of Medicine, Zhejiang University104 enrolled1 locationNCT06240689
Completed
Phase 2

Chemoradiation Treatment for Head and Neck Cancer

Locally Advanced Head and Neck Squamous Cell Carcinoma
Trans Tasman Radiation Oncology Group60 enrolled1 locationACTRN12613000695707