Locally Advanced or Metastatic Solid Tumors Clinical Trials

15 recruiting

Locally Advanced or Metastatic Solid Tumors Trials at a Glance

17 actively recruiting trials for locally advanced or metastatic solid tumors are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Phase 1 with 16 trials, with the heaviest enrollment activity in Beijing, Shanghai, and Guangzhou. Lead sponsors running locally advanced or metastatic solid tumors studies include Avistone Biotechnology Co., Ltd., Innovent Biologics (Suzhou) Co. Ltd., and ArriVent BioPharma, Inc..

Browse locally advanced or metastatic solid tumors trials by phase

Treatments under study

About Locally Advanced or Metastatic Solid Tumors Clinical Trials

Looking for clinical trials for Locally Advanced or Metastatic Solid Tumors? There are currently 15 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Locally Advanced or Metastatic Solid Tumors trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Locally Advanced or Metastatic Solid Tumors clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Phase 1

A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors
Avistone Biotechnology Co., Ltd.63 enrolled15 locationsNCT06307795
Recruiting
Phase 1

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Esophageal CancerGastric CancerCervical Cancer+5 more
Genentech, Inc.450 enrolled41 locationsNCT05581004
Recruiting
Phase 1

Study of XB010 in Subjects With Solid Tumors

Locally Advanced or Metastatic Solid TumorsNSCLC (Non-small Cell Lung Cancer)Esophageal Squamous Cell Cancer+1 more
Exelixis396 enrolled19 locationsNCT06545331
Recruiting
Phase 1

A Study to Investigate ANS03 in Participants With Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors Harboring a ROS1 or NTRK Alteration
Avistone Biotechnology Co., Ltd.96 enrolled5 locationsNCT06716138
Recruiting
Phase 1

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors
ArriVent BioPharma, Inc.405 enrolled15 locationsNCT07066657
Recruiting
Phase 1Phase 2

IBI3014 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors

Unresectable Locally Advanced or Metastatic Solid Tumors
Innovent Biologics (Suzhou) Co. Ltd.250 enrolled3 locationsNCT06974812
Recruiting
Phase 2

A Study of YL202 in Selected Patients With Advanced Solid Tumors

Breast CancerNSCLCHNSCC+1 more
MediLink Therapeutics (Suzhou) Co., Ltd.200 enrolled82 locationsNCT06107686
Recruiting
Phase 1

A Study of BL-M05D1 in Patients With Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors
Sichuan Baili Pharmaceutical Co., Ltd.30 enrolled1 locationNCT06349811
Recruiting
Phase 1

A Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of ATG 037 Monotherapy and Combination Therapy With Pembrolizumab in Patients With Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors
Antengene Therapeutics Limited98 enrolled7 locationsNCT05205109
Recruiting
Phase 1Phase 2

A Study to Investigate the Safety, Pharmacokinetics, and Clinical Activity of AP203 in Patients with Locally Advanced or Metastatic Solid Tumors, and Expansion to Selected Malignancies

Locally Advanced or Metastatic Solid Tumors
AP Biosciences Inc.168 enrolled1 locationNCT05473156
Recruiting
Phase 1Phase 2

PTT-936 Alone or in Combination in Patients With Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors
Pyrotech Therapeutics, Inc.68 enrolled3 locationsNCT06244992
Recruiting
Phase 1Phase 2

Clinical Trial to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of DA-4505 as a Single Agent and in Combination With Pembrolizumab in Adult Patients With Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors
Dong-A ST Co., Ltd.125 enrolled2 locationsNCT06293651
Recruiting
Phase 1

Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid TumorsUnresectable
Innovent Biologics (Suzhou) Co. Ltd.198 enrolled1 locationNCT06418061
Recruiting
Phase 1

A Study of TYK-00540 in Adult Patients With Solid Tumors

Locally Advanced or Metastatic Solid Tumors
TYK Medicines, Inc156 enrolled1 locationNCT06246071
Recruiting
Phase 1Phase 2

IFNα Expressing Mesenchymal Stromal Cells for Locally Advanced/Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors
Chinese PLA General Hospital40 enrolled1 locationNCT05699811
Recruiting
Phase 1

Phase I study to evaluate Safety and Tolerability of RX108-A Tablets in Patients with advanced Cancer

Locally Advanced or Metastatic Solid Tumors
NeuPharma Pty Ltd20 enrolled2 locationsACTRN12623000307606
Recruiting
Phase 1Phase 2

A Study of XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Non-small Cell Lung CancerLocally Advanced or Metastatic Solid Tumors
Xuanzhu Biopharmaceutical Co., Ltd.360 enrolled1 locationNCT04996121