Phase 2 Low-grade Glioma Clinical Trials
11 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–11 of 11 trials
Recruiting
Phase 2
Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco96 enrolled7 locationsNCT07110246
Recruiting
Phase 1Phase 2
Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK
Pediatric Low-grade Glioma
St. Justine's Hospital50 enrolled8 locationsNCT06666348
Recruiting
Phase 2
Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial
Malignant Brain NeoplasmMeningiomaLow-grade Glioma+1 more
Emory University200 enrolled1 locationNCT06132685
Recruiting
Phase 1Phase 2
SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma
Low-grade GliomaRecurrent Low Grade GliomaProgressive Low-Grade Glioma
St. Jude Children's Research Hospital132 enrolled1 locationNCT04923126
Recruiting
Phase 2
A Vaccine Trial for Low Grade Gliomas
Low-grade Glioma
James Felker25 enrolled1 locationNCT02358187
Recruiting
Phase 1Phase 2
MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas
High Grade GliomaLow-grade Glioma
Ann & Robert H Lurie Children's Hospital of Chicago27 enrolled3 locationsNCT06712875
Recruiting
Phase 2
A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
Advanced Solid TumorLow-grade Glioma
Day One Biopharmaceuticals, Inc.141 enrolled35 locationsNCT04775485
Recruiting
Phase 2
FG001 in Subjects with Meningiomas or Presumed Low-Grade Gliomas Scheduled for Neurosurgery
MeningiomaGliomaLow-grade Glioma
Rigshospitalet, Denmark40 enrolled1 locationNCT06684795
Recruiting
Phase 2
Feasibility of Individualized, Model-guided Optimization of Proton Beam Treatment Planning in Patients With Low Grade Glioma
Low-grade Glioma
University Hospital Heidelberg120 enrolled1 locationNCT05964569
Recruiting
Phase 2
Binimetinib in Patients With BRAF Fusion-positive Low-grade Glioma or Pancreatic Cancer (Perfume)
Pancreatic CancerLow-grade Glioma
National Cancer Center, Japan32 enrolled6 locationsNCT06159478
Recruiting
Phase 2Phase 3
Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery
Low-grade Glioma
West China Hospital250 enrolled1 locationNCT04316039