Phase 2 Lung Cancer Metastatic Clinical Trials

14 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 114 of 14 trials

Recruiting
Phase 2

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Lung CancerBrain Metastases, AdultBrain Metastases+3 more
Memorial Sloan Kettering Cancer Center62 enrolled7 locationsNCT05419076
Recruiting
Phase 2

A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC)

Non-small Cell Lung CancerNSCLCNon-small Cell Lung Cancer Metastatic+2 more
Memorial Sloan Kettering Cancer Center68 enrolled9 locationsNCT05657873
Recruiting
Phase 2

A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain

Non-small Cell Lung Cancer Metastatic
Memorial Sloan Kettering Cancer Center56 enrolled8 locationsNCT06741085
Recruiting
Phase 2

Lazertinib & Tepotinib for EGFR Mutant NSCLC in MET Overexpressed or Amplified Who Progressed After Lazertinib Treatment

Non-small Cell Lung Cancer Metastatic
Samsung Medical Center47 enrolled1 locationNCT06106802
Recruiting
Phase 2

Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer

Non-small Cell Lung CancerNon-small Cell Lung Cancer MetastaticNon-small Cell Lung Cancer Stage IV+2 more
University of California, Davis56 enrolled1 locationNCT07250477
Recruiting
Phase 1Phase 2

A Phase 1b/2 Study of the Safety and Efficacy of the Monoclonal Antibody OM-RCA-01 in Patients With Metastatic Tumors Expressing Fibroblast Growth Factor Receptor 1

Breast Cancer MetastaticRenal Cell Carcinoma MetastaticProstate Cancer Metastatic+2 more
Kidney Cancer Research Bureau58 enrolled5 locationsNCT07292168
Recruiting
Phase 2

PALACE: Cemiplimab Trial According to ctDNA Levels

Non-small Cell Lung Cancer MetastaticThoracic NeoplasmsStage IV Non-Small Cell Lung Cancer+3 more
Fundación GECP63 enrolled20 locationsNCT06917573
Recruiting
Phase 1Phase 2

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

Advanced CancerLung Cancer (Non-Small Cell)Solid Tumor, Adult+2 more
Krystal Biotech, Inc.250 enrolled14 locationsNCT06228326
Recruiting
Phase 2

High-dose Furmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed Chemotherapy in Patients With EGFR-mutated Non-small Cell Lung Cancer and Meningeal Metastasis

Non-small Cell Lung Cancer Metastatic
Sun Yat-sen University30 enrolled1 locationNCT06812871
Recruiting
Phase 1Phase 2

TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer

Lung CancerLung Cancer (Non-Small Cell)Lung Cancer Metastatic+1 more
Essen Biotech85 enrolled1 locationNCT06538012
Recruiting
Phase 2

Befotertinib and Icotinib for NSCLC With Uncommon EGFR Mutations

Non-small Cell Lung Cancer MetastaticEGFR G719XEGFR L861Q+1 more
Sun Yat-sen University23 enrolled1 locationNCT06517953
Recruiting
Phase 2

A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib

Non-small Cell Lung Cancer MetastaticALK Gene Mutation
Centro di Riferimento Oncologico - Aviano45 enrolled9 locationsNCT06378892
Recruiting
Phase 2

Stereotactic Ablative Radiotherapy for Oligo-Progressive Non Small Cell Lung Cancer

Lung Cancer Metastatic
Centre hospitalier de l'Université de Montréal (CHUM)68 enrolled1 locationNCT04405401
Active
Phase 2

Durvalumab and Tremelimumab +/- Platinum-Based Chemotherapy in Patients With Metastatic Squamous or Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Lung Cancer Metastatic
NHMRC Clinical Trials Centre80 enrolled10 locationsACTRN12617001468314