Early Phase 1 Lung Cancer Clinical Trials

13 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 113 of 13 trials

Recruiting
Early Phase 1

Testing the Safety of Dapagliflozin Prior to Surgery for the Treatment of Patients With Stage IA Lung Adenocarcinoma

Lung CancerLung AdenocarcinomaStage IA1 Lung Cancer American Joint Committee on Cancer (AJCC) v8+2 more
Jonsson Comprehensive Cancer Center48 enrolled1 locationNCT07235280
Recruiting
Early Phase 1

Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer

Stage IV Lung Cancer AJCC v8Stage IVA Lung Cancer AJCC v8Stage IVB Lung Cancer AJCC v8+1 more
Emory University15 enrolled1 locationNCT05493566
Recruiting
Early Phase 1

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

Lung CancerSmall Cell Lung Carcinoma
UNC Lineberger Comprehensive Cancer Center24 enrolled1 locationNCT05620342
Recruiting
Early Phase 1

[177Lu]Lu-AKIR001 First-in-human Study

Thyroid Gland Anaplastic CarcinomaPoorly Differentiated Thyroid CarcinomaCancer Head and Neck+3 more
Karolinska University Hospital15 enrolled1 locationNCT06639191
Recruiting
Early Phase 1

Universal CAR-T Cells (REVO-UWD-03) for Advanced Hepatocellular Carcinoma and Lung Cancer

NSCLC (Advanced Non-small Cell Lung Cancer)HCC - Hepatocellular Carcinoma
Wondercel Biotech (ShenZhen)60 enrolled2 locationsNCT06653023
Recruiting
Early Phase 1

Inhaled mRNA Tumor-associated Antigen Dry Powder Vaccine in Advanced Lung Cancer and Lung Metastasis of Solid Tumors.

Advanced Lung CancerLung Metastasis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences83 enrolled1 locationNCT06928922
Recruiting
Early Phase 1

TC-D101 Cell Therapy for Patients With DLL3-Positive SCLC

Small Cell Lung Cancer ( SCLC )CAR-T Cell Therapy
TCRCure Biopharma Ltd.24 enrolled1 locationNCT07246304
Recruiting
Early Phase 1

EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer

EGFR/ B7H3-positive Advanced Lung CancerEGFR/ B7H3-positive Advanced Triple-negative Breast Cancer
Second Affiliated Hospital of Guangzhou Medical University30 enrolled1 locationNCT05341492
Recruiting
Early Phase 1

WTX212A Monotherapy and in Combination With PD -1/PD-L1 Monoclonal Antibody

Advanced Lung Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University20 enrolled1 locationNCT06106152
Recruiting
Early Phase 1

Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

Non-small Cell Lung Cancer
State University of New York - Upstate Medical University12 enrolled1 locationNCT02619448
Recruiting
Early Phase 1

DC Combined With ICIs in the Treatment of Advanced Lung Cancer Resistant to ICIs

Lung Cancer
Zhen-Yu Ding20 enrolled1 locationNCT06329908
Recruiting
Early Phase 1

A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors

Breast CancerSarcomaLung Cancer+7 more
Shanghai Yunying Medical Technology20 enrolled1 locationNCT05961111
Terminated
Early Phase 1

Quantifying the Clinical Benefit of Magnetic Resonance Imaging (MRI) in Lung Cancer Radiotherapy

Lung Cancer
Liverpool Cancer Therapy Centre36 enrolled2 locationsACTRN12616001075471