Early Phase 1 Lymphoma Clinical Trials

44 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 120 of 44 trials

Recruiting
Early Phase 1

64Cu-LLP2A for Imaging Hematologic Malignancies

Chronic Lymphocytic LeukemiaMultiple MyelomaFollicular Lymphoma+4 more
Washington University School of Medicine42 enrolled1 locationNCT06636175
Recruiting
Early Phase 1

Exercise as an Immune Adjuvant for Allogeneic Cell Therapies

LymphomaLeukemiaCAR-T Cell Therapy+3 more
University of Arizona200 enrolled1 locationNCT06643221
Recruiting
Early Phase 1

Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib

Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
National Heart, Lung, and Blood Institute (NHLBI)30 enrolled1 locationNCT07428707
Recruiting
Early Phase 1

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

transitional cell carcinomaSoft Tissue SarcomaMelanoma+12 more
University of California, Irvine25 enrolled1 locationNCT07628634
Recruiting
Early Phase 1

A Study of Automated Axicabtagene Ciloleucel for R/R Large B-cell Lymphoma.

Relapsed/Refractory Large B-Cell Lymphoma
Shenzhen Fosun Kairos Biotechnology Co., Ltd.12 enrolled6 locationsNCT07606937
Recruiting
Early Phase 1

A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

Plasmablastic LymphomaAnn Arbor Stage I Diffuse Large B-Cell LymphomaAnn Arbor Stage II Diffuse Large B-Cell Lymphoma+2 more
AIDS Malignancy Consortium15 enrolled8 locationsNCT04139304
Recruiting
Early Phase 1

A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia

Chronic Lymphocytic Leukemia (CLL)B-cell Acute Lymphoblastic Leukemia (B-ALL)Autoimmune Hemolytic Anemia, AIHA+1 more
Grit Biotechnology28 enrolled2 locationsNCT07205315
Recruiting
Early Phase 1

An Open-label, Single-arm, Multicenter Phase II Clinical Study of Azacitidine, Chidamide Combined With PD-1 Monoclonal Antibody in the Treatment of Refractory/Relapsed Peripheral T-cell Lymphoma.

Peripheral T-Cell Lymphoma Refractory
Second Affiliated Hospital of Soochow University30 enrolled1 locationNCT07598578
Recruiting
Early Phase 1

A Clinical Study Exploring the Safety, Efficacy and Metabolic Kinetics of CT1182 Injection in Patients With Relapsed / Refractory Non Hodgkin Lymphoma

DLBCL - Diffuse Large B Cell LymphomaFollicular Lymphoma ( FL)B-cell Non Hodgkin Lymphoma (NHL)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology24 enrolled1 locationNCT07548697
Recruiting
Early Phase 1

A Phase I/IIa, Open-label, Single-center, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of IMV101 as a Single Agent in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Relapsed/Refractory B- Cell Non-Hodgkin Lymphoma
Suzhou Immunofoco Biotechnology Co., Ltd30 enrolled4 locationsNCT07376642
Recruiting
Early Phase 1

Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma

Lymphoma
Mayo Clinic60 enrolled1 locationNCT05294367
Recruiting
Early Phase 1

Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

Diffuse Large B Cell LymphomaB-ALLDLBCL Unclassifiable+7 more
Memorial Sloan Kettering Cancer Center12 enrolled7 locationsNCT04512716
Recruiting
Early Phase 1

In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET

Non-Hodgkin LymphomaMultiple MyelomaErdheim-Chester Disease+2 more
Memorial Sloan Kettering Cancer Center30 enrolled1 locationNCT05093335
Recruiting
Early Phase 1

Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma
City of Hope Medical Center9 enrolled1 locationNCT05800405
Recruiting
Early Phase 1

Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma

Lymphoma, B-Cell
Canadian Cancer Trials Group18 enrolled4 locationsNCT04161248
Recruiting
Early Phase 1

Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy

Breast CancerLymphoma
University of Oklahoma104 enrolled2 locationsNCT05921253
Recruiting
Early Phase 1

Universal CAR-T Cells (REVO-UWD-19) for Refractory and Relapsed B-Cell Tumors

B-cell LymphomaB-cell MalignancyB-Cell Leukemia
Wondercel Biotech (ShenZhen)30 enrolled1 locationNCT06662227
Recruiting
Early Phase 1

CART123 T Cells in Relapsed or Refractory CD123+ Hematologic Malignancies: A Dose Escalation Phase I Trial

Myelodysplastic Syndromes (MDS)Precursor Cell Lymphoblastic Leukemia-LymphomaBlastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)+1 more
Institute of Hematology and Blood Transfusion, Czech Republic18 enrolled1 locationNCT06765876
Recruiting
Early Phase 1

An Open and Dose-escalation Early Clinical Study of CD19 and CD20 CAR-T Cell Therapy for Relapsed or Refractory Aggressive B-cell Lymphoma

R/R Aggressive B-cell Lymphoma
Peking University People's Hospital18 enrolled1 locationNCT07344818
Recruiting
Early Phase 1

A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in Adult Participants With Relapsed/Refractory CD19-positive B-cell Malignant Hematological Tumors

Hematological Malignancy (Leukemia- Lymphoma)
Grit Biotechnology34 enrolled1 locationNCT07131254