Early Phase 1 Lymphoma Clinical Trials
40 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 40 trials
Recruiting
Early Phase 1
Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib
Chronic Lymphocytic Leukemia (CLL)Small Lymphocytic Lymphoma (SLL)
National Heart, Lung, and Blood Institute (NHLBI)30 enrolled1 locationNCT07428707
Recruiting
Early Phase 1
Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma
Lymphoma
Mayo Clinic60 enrolled1 locationNCT05294367
Recruiting
Early Phase 1
Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma
Diffuse Large B Cell LymphomaB-ALLDLBCL Unclassifiable+7 more
Memorial Sloan Kettering Cancer Center12 enrolled7 locationsNCT04512716
Recruiting
Early Phase 1
In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET
Non-Hodgkin LymphomaMultiple MyelomaErdheim-Chester Disease+2 more
Memorial Sloan Kettering Cancer Center30 enrolled1 locationNCT05093335
Recruiting
Early Phase 1
Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma
Recurrent Diffuse Large B-Cell LymphomaRefractory Diffuse Large B-Cell Lymphoma
City of Hope Medical Center9 enrolled1 locationNCT05800405
Recruiting
Early Phase 1
Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma
Lymphoma, B-Cell
Canadian Cancer Trials Group18 enrolled4 locationsNCT04161248
Recruiting
Early Phase 1
Neuromodulation of Cardiovascular Risks Associated With Cardiotoxic Chemotherapy
Breast CancerLymphoma
University of Oklahoma104 enrolled2 locationsNCT05921253
Recruiting
Early Phase 1
Universal CAR-T Cells (REVO-UWD-19) for Refractory and Relapsed B-Cell Tumors
B-cell LymphomaB-cell MalignancyB-Cell Leukemia
Wondercel Biotech (ShenZhen)30 enrolled1 locationNCT06662227
Recruiting
Early Phase 1
CART123 T Cells in Relapsed or Refractory CD123+ Hematologic Malignancies: A Dose Escalation Phase I Trial
Myelodysplastic Syndromes (MDS)Precursor Cell Lymphoblastic Leukemia-LymphomaBlastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)+1 more
Institute of Hematology and Blood Transfusion, Czech Republic18 enrolled1 locationNCT06765876
Recruiting
Early Phase 1
An Open and Dose-escalation Early Clinical Study of CD19 and CD20 CAR-T Cell Therapy for Relapsed or Refractory Aggressive B-cell Lymphoma
R/R Aggressive B-cell Lymphoma
Peking University People's Hospital18 enrolled1 locationNCT07344818
Recruiting
Early Phase 1
A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in Adult Participants With Relapsed/Refractory CD19-positive B-cell Malignant Hematological Tumors
Hematological Malignancy (Leukemia- Lymphoma)
Grit Biotechnology34 enrolled1 locationNCT07131254
Recruiting
Early Phase 1
A Clinical Study Evaluating the Safety and Efficacy of GT801 Injection in Adult Patients With Relapsed/Refractory CD19-positive B-cell Hematologic Malignancies and Autoimmune Hemolytic Anemia
Chronic Lymphocytic Leukemia (CLL)B-cell Acute Lymphoblastic Leukemia (B-ALL)Autoimmune Hemolytic Anemia, AIHA+1 more
Grit Biotechnology28 enrolled2 locationsNCT07205315
Recruiting
Early Phase 1
Clinical Study of LV009 Injection for the Treatment of Relapsed/Refractory CD19-Positive Hematologic and Lymphoid Malignancies
Acute Lymphoblastic Leukemia (ALL), AdultNon-Hodgkin Lymphoma (NHL)
PersonGen BioTherapeutics (Suzhou) Co., Ltd.19 enrolled1 locationNCT07312630
Recruiting
Early Phase 1
Safety and Efficacy of Anti-EBV Autologous TCR-T Cell Injection in Relapsed/Refractory EBV-Positive Lymphoma
DLBCLNK/T-cell LymphomaPeripheral T-cell Lymphoma (PTCL)
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine24 enrolled1 locationNCT07162012
Recruiting
Early Phase 1
Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies
Chronic Myeloid LeukemiaHodgkin LymphomaNon-Hodgkin Lymphoma+9 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of r/r DLBCL Clinical Research
Diffuse Large B Cell Lymphoma
He Huang18 enrolled1 locationNCT06120166
Recruiting
Early Phase 1
An Open-label, Single-arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of OriV508 Injection in Treating Relapsed/Refractory Hematological Malignancies
Non-Hodgkin Lymphoma (NHL)Multiple Myeloma (MM)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology40 enrolled1 locationNCT07101705
Recruiting
Early Phase 1
A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL)
Non-hodgkin Lymphoma,B Cell
Shanghai Cell Therapy Group Co.,Ltd20 enrolled1 locationNCT06446128
Recruiting
Early Phase 1
Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
B-cell Non-Hodgkin Lymphoma Recurrent B-cell Non-Hodgkin Lymphoma Refractory
Beijing GoBroad Hospital48 enrolled3 locationsNCT07093411
Recruiting
Early Phase 1
Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma
NK-Cell LymphomaPeripheral T Cell LymphomaNK-Cell Leukemia
New York Medical College40 enrolled6 locationsNCT03719105