Phase 1 Lymphoma, Non-Hodgkin Clinical Trials
15 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–15 of 15 trials
Recruiting
Phase 1Phase 2
A Clinical Study of MK-1045 in People With Non-Hodgkin Lymphoma (MK-1045-008)
Lymphoma, Non-HodgkinLymphoma, FollicularLymphoma, Large B-Cell, Diffuse
Merck Sharp & Dohme LLC200 enrolled4 locationsNCT07519772
Recruiting
Phase 1Phase 2
CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies
Acute Lymphoblastic LeukemiaLymphoma, Non-HodgkinB-cell Lymphoma+8 more
National Cancer Institute (NCI)130 enrolled1 locationNCT05442515
Recruiting
Phase 1
A Study of JNJ-95566692 in Participants With Non-Hodgkin Lymphoid Malignancies
Lymphoma, Non-Hodgkin
Janssen Research & Development, LLC130 enrolled9 locationsNCT07308132
Recruiting
Phase 1Phase 2
A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma
Lymphoma, Non-HodgkinLymphoma, B-CellLymphoma, Large B-Cell, Diffuse
Janssen Research & Development, LLC439 enrolled32 locationsNCT05421663
Recruiting
Phase 1
A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers
Follicular LymphomaLymphoma Diffuse Large B-cellLymphoma, Non-Hodgkin's
Eli Lilly and Company460 enrolled46 locationsNCT07226843
Recruiting
Phase 1
A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies
Lymphoma, B-CellChronic Lymphocytic Leukemia (CLL)Lymphoma, Non-Hodgkin (NHL)+1 more
Umoja Biopharma106 enrolled8 locationsNCT06528301
Recruiting
Phase 1
TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas
LymphomaLymphoma, Non-Hodgkin
Treeline Biosciences, Inc.180 enrolled12 locationsNCT07082803
Recruiting
Phase 1
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
Triple-Negative Breast CancerHead and Neck Squamous Cell CarcinomaMetastatic Cancer+11 more
OncoNano Medicine, Inc.168 enrolled16 locationsNCT06022029
Recruiting
Phase 1
DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Lymphoma, Non-Hodgkin
Dizal Pharmaceuticals230 enrolled5 locationsNCT05824585
Recruiting
Phase 1Phase 2
T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)
High-grade B-cell LymphomaNon-Hodgkin LymphomaLymphoma+12 more
Estrella Biopharma, Inc.21 enrolled2 locationsNCT06343311
Recruiting
Phase 1Phase 2
A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies
Lymphoma, Non-HodgkinLymphoma, B-CellLarge B-cell Lymphoma+3 more
Cancer Research UK84 enrolled7 locationsNCT06045910
Recruiting
Phase 1
Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma
Diffuse Large B Cell LymphomaLymphoma, Non-HodgkinFollicular Lymphoma
Weill Medical College of Cornell University38 enrolled1 locationNCT05618366
Recruiting
Phase 1
CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
Non-Hodgkin LymphomaLymphomaLymphoma, Non-Hodgkin+4 more
Caribou Biosciences, Inc.72 enrolled38 locationsNCT04637763
Recruiting
Phase 1Phase 2
CD19-directed CAR-T Cell Therapy for R/R Acute Leukemia and Lymphoma
Lymphoma, Non-HodgkinLeukemia, Acute Lymphoblastic
University of Sao Paulo81 enrolled5 locationsNCT06101381
Recruiting
Phase 1
Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Non-Hodgkin Lymphoma
Lymphoma, Non-Hodgkin Lymphoma, B-Cell
Luminary Therapeutics20 enrolled2 locationsNCT05312801