Phase 1 Lymphoma, Non-Hodgkin Clinical Trials

10 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 110 of 10 trials

Recruiting
Phase 1

A Study of JNJ-95566692 in Participants With Non-Hodgkin Lymphoid Malignancies

Lymphoma, Non-Hodgkin
Janssen Research & Development, LLC130 enrolled8 locationsNCT07308132
Recruiting
Phase 1Phase 2

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Lymphoma, Non-HodgkinLymphoma, B-CellLymphoma, Large B-Cell, Diffuse
Janssen Research & Development, LLC439 enrolled32 locationsNCT05421663
Recruiting
Phase 1

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

Lymphoma, B-CellChronic Lymphocytic Leukemia (CLL)Lymphoma, Non-Hodgkin (NHL)+1 more
Umoja Biopharma106 enrolled8 locationsNCT06528301
Recruiting
Phase 1

DZD8586 in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin
Dizal Pharmaceuticals230 enrolled5 locationsNCT05824585
Recruiting
Phase 1Phase 2

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

Non-Hodgkin LymphomaNon-Hodgkin's LymphomaLymphomas Non-Hodgkin's B-Cell+2 more
Estrella Biopharma, Inc.21 enrolled2 locationsNCT06343311
Recruiting
Phase 1Phase 2

A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies

Lymphoma, Non-HodgkinLymphoma, B-CellLarge B-cell Lymphoma+3 more
Cancer Research UK84 enrolled7 locationsNCT06045910
Recruiting
Phase 1

Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma

Diffuse Large B Cell LymphomaLymphoma, Non-HodgkinFollicular Lymphoma
Weill Medical College of Cornell University38 enrolled1 locationNCT05618366
Recruiting
Phase 1

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Lymphoma, Non-HodgkinRefractory B-Cell Non-Hodgkin LymphomaRelapsed Non Hodgkin Lymphoma
Caribou Biosciences, Inc.72 enrolled38 locationsNCT04637763
Recruiting
Phase 1Phase 2

CD19-directed CAR-T Cell Therapy for R/R Acute Leukemia and Lymphoma

Lymphoma, Non-HodgkinLeukemia, Acute Lymphoblastic
University of Sao Paulo81 enrolled5 locationsNCT06101381
Recruiting
Phase 1

Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Non-Hodgkin Lymphoma

Lymphoma, Non-Hodgkin Lymphoma, B-Cell
Luminary Therapeutics20 enrolled2 locationsNCT05312801