Phase 3 Macular Edema Clinical Trials

12 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 112 of 12 trials

Recruiting
Phase 3

Clinical Study to Compare Efficacy and Safety of AVT29 and Eylea HD in Participants With Diabetic Macular Edema

Diabetic Macular Edema
Alvotech Swiss AG256 enrolled1 locationNCT07489131
Recruiting
Phase 3

COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled39 locationsNCT07449936
Recruiting
Phase 3

CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled38 locationsNCT07449923
Recruiting
Phase 3

Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)
Bio-Thera Solutions406 enrolled50 locationsNCT07515079
Recruiting
Phase 3

A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME

Diabetic Macular Edema
Hoffmann-La Roche634 enrolled92 locationsNCT04108156
Recruiting
Phase 3

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

Macular Edema Secondary to Inflammation
Kodiak Sciences Inc150 enrolled33 locationsNCT06996080
Recruiting
Phase 3

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

Macular Edema Secondary to Inflammation
Kodiak Sciences Inc150 enrolled33 locationsNCT06990399
Recruiting
Phase 3

A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edema

Retinal DegenerationMacular DegenerationDiabetic Retinopathy+3 more
Incepta Pharmaceuticals Ltd70 enrolled1 locationNCT06305416
Recruiting
Phase 3

Combination of Ranibizumab and Targeted Laser Photocoagulation

Central Retinal Vein Occlusion With Macular Edema
University of Giessen110 enrolled15 locationsNCT04444492
Recruiting
Phase 2Phase 3

Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin

Diabetic Macular EdemaMacular EdemaRetinal Neovascularization
Isfahan University of Medical Sciences52 enrolled1 locationNCT06595355
Recruiting
Phase 3

Efficacy and Safety of RC28-E Versus Aflibercept in Diabetic Macular Edema

Diabetic Macular Edema
RemeGen Co., Ltd.316 enrolled1 locationNCT05885503
Recruiting
Phase 3

Efficacy of intravitreal triamcinolone acetonide before pan retinal photocoagulation for improvement of visual acuity and macular edema in diabetic retinopathy

Diabetic macular edema in severe non proliferative diabetic retinopathy (NPDR)or proliferative diabetic retinopathy(PDR)
Eye Research Center, Farabi Eye Hospital60 enrolled1 locationACTRN12607000225415