Early Phase 1 Melanoma Clinical Trials

10 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 110 of 10 trials

Recruiting
Early Phase 1

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

transitional cell carcinomaSoft Tissue SarcomaMelanoma+12 more
University of California, Irvine25 enrolled1 locationNCT07628634
Recruiting
Early Phase 1

Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma

Locally Advanced or Metastatic Melanoma
Fox Chase Cancer Center12 enrolled1 locationNCT05498792
Recruiting
Early Phase 1

Efficacy and Safety of Neoadjuvant Cadonilimab Plus High-Dose Recombinant Human Interferon α1b in Stage III/IV Melanoma.

Melanoma (Skin Cancer)
Xijing Hospital10 enrolled1 locationNCT07586904
Recruiting
Early Phase 1

RP1 in Primary Melanoma to Reduce the Risk of Sentinel Lymph Node Metastasis

Melanoma
Yana Najjar25 enrolled1 locationNCT06216938
Recruiting
Early Phase 1

Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma

Melanoma Stage IVBRAF V600 MutationMelanoma Stage III
H. Lee Moffitt Cancer Center and Research Institute50 enrolled1 locationNCT04741997
Recruiting
Early Phase 1

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

Endometrial CancerNon-small Cell Lung CancerTNBC - Triple-Negative Breast Cancer+6 more
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06305962
Recruiting
Early Phase 1

A Study of GC101 TIL in Advanced Melanoma (10hospital)

Advanced MelanomaTreatment Side EffectsEffects of Immunotherapy+1 more
Shanghai Juncell Therapeutics50 enrolled1 locationNCT05098184
Recruiting
Early Phase 1

FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma

Advanced Melanoma
University of Virginia11 enrolled1 locationNCT06472661
Recruiting
Early Phase 1

A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors

Breast CancerSarcomaLung Cancer+7 more
Shanghai Yunying Medical Technology20 enrolled1 locationNCT05961111
Active
Early Phase 1

Can reduced dose radiotherapy delivered in standard fractionation improve the therapeutic index for stereotactic treatment of juxtapapillary choroidal melanoma?

Juxtapapillary choroidal melanoma
Peter MacCallum Cancer Centre20 enrolled1 locationACTRN12614000531617