Phase 2 Melanoma Clinical Trials

16 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 116 of 16 trials

Recruiting
Phase 1Phase 2

A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors

MelanomaNon-small Cell Lung CancerSquamous Cell Carcinoma (Skin)+2 more
AstraZeneca60 enrolled11 locationsNCT07115043
Recruiting
Phase 2

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Breast CancerEsophageal CancerGastric Cancer+11 more
Daiichi Sankyo740 enrolled84 locationsNCT06172478
Recruiting
Phase 1Phase 2

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Breast CancerPancreatic CancerOvarian Cancer+2 more
National Cancer Institute (NCI)124 enrolled1 locationNCT02830724
Recruiting
Phase 2

Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

Malignant Solid NeoplasmMelanomaRenal Cell Carcinoma+1 more
City of Hope Medical Center32 enrolled1 locationNCT05830058
Recruiting
Phase 2

The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas

Breast CarcinomaUrothelial CarcinomaOvarian Carcinoma+26 more
Mayo Clinic27 enrolled1 locationNCT07285044
Recruiting
Phase 2Phase 3

Contrast-enhanced Ultrasound for Sentinel Node Detection

Breast CancerMelanomaHead & Neck Cancer
The Netherlands Cancer Institute91 enrolled1 locationNCT07310758
Recruiting
Phase 2Phase 3

DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers.

MelanomaOvarian NeoplasmsColorectal Neoplasms+3 more
Cancer Research UK30 enrolled16 locationsNCT05768178
Recruiting
Phase 1Phase 2

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

Cervical CancerMelanomaBladder Cancer+6 more
University of Arizona30 enrolled1 locationNCT06814496
Recruiting
Phase 1Phase 2

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

MelanomaAdvanced Solid TumorMetastasis+5 more
7 Hills Pharma, LLC126 enrolled4 locationsNCT06362369
Recruiting
Phase 1Phase 2

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

Lung CancerMelanomaMetastatic Lung Cancer+2 more
Obsidian Therapeutics, Inc.52 enrolled9 locationsNCT06060613
Recruiting
Phase 2

Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL)

Melanoma
Vall d'Hebron Institute of Oncology40 enrolled1 locationNCT06630611
Recruiting
Phase 2

A Study of IBI363 in Subjects with Advanced Solid Malignancies

MelanomaNon-small Cell Lung Cancer
Innovent Biologics (Suzhou) Co. Ltd.178 enrolled9 locationsNCT06281678
Recruiting
Phase 1Phase 2

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

MelanomaCancerSolid Tumor+1 more
Simcha IL-18, Inc.316 enrolled6 locationsNCT04787042
Recruiting
Phase 2

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Breast CancerLung CancerMelanoma+3 more
Dana-Farber Cancer Institute134 enrolled2 locationsNCT04899908
Recruiting
Phase 2Phase 3

Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors

Breast CancerOvarian CancerCervical Cancer+7 more
Second Affiliated Hospital of Guangzhou Medical University200 enrolled1 locationNCT03755739
Recruiting
Phase 2

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations

Lung CancerMelanomaPancreas Cancer+4 more
N.N. Petrov National Medical Research Center of Oncology20 enrolled1 locationNCT06229340