Melasma Clinical Trials

10 recruiting

Frequently Asked Questions

Common questions about Melasma clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Not Applicable

Ultrasound-Enhanced Delivery of Compound TXA Solution in Melasma

Melasma (Facial Melasma)
The First Affiliated Hospital with Nanjing Medical University35 enrolled1 locationNCT07202156
Recruiting
Not Applicable

COMPARISON OF A COSMETIC SERUM AND 4% HYDROQUINONE FOR TREATING MELASMA OVER 84 DAYS

HealthyMelasma (Facial Melasma)Epidermal Melasma
Laboratoire Dermatologique ACM40 enrolled1 locationNCT07071363
Recruiting
Not Applicable

Stem Cell Derived Exosomes in the Treatment of Melasma and Its Percutaneous Penetration

Melasma
Fujian Medical University Union Hospital80 enrolled1 locationNCT06221787
Recruiting
Phase 1Phase 2

Oral Metformin for Treating Melasma in Latin American Women

Melasma
University of Puerto Rico30 enrolled1 locationNCT06845540
Recruiting
Phase 2

Randomized Study Using SM-030 Gel for Adults With Melasma

Melasma
DermBiont, Inc.138 enrolled2 locationsNCT06454747
Recruiting
Not Applicable

The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis

MelasmaRosaceaAcne+1 more
Integrative Skin Science and Research150 enrolled1 locationNCT05942248
Recruiting
Not Applicable

Fractional Erbium YAG Laser vs Intradermal and Systemic Tranexamic Acid

Refractory Melasma
Egymedicalpedia45 enrolled1 locationNCT06522984
Recruiting
Not Applicable

Development of Products Based on Secretom From Stem Cell Conditioned Medium for Melasma Therapy

Melasma
Dr.dr.Irma Bernadette, SpKK (K)90 enrolled2 locationsNCT06516419
Recruiting
Not Applicable

Sylfirm X Radiofrequency Microneedling for the Treatment of Melasma

Melasma
Benev Company, Inc.90 enrolled3 locationsNCT06415435