Phase 2 Metastatic Colorectal Cancer Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 113 of 13 trials

Recruiting
Phase 2

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Metastatic Breast CarcinomaMetastatic Ovarian CancerMetastatic Pancreatic Cancer+2 more
National Cancer Institute (NCI)332 enrolled1 locationNCT01174121
Recruiting
Phase 2

Cetuximab and Envafolimab Plus mFOLFOXIRI as First-line Treatment for RAS/BRAF Wild-type, MSS, Unresectable Left-side Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
Sun Yat-sen University198 enrolled3 locationsNCT05959356
Recruiting
Phase 1Phase 2

A FIH, Phase I/IIa, Trial Assessing Feasibility of Administrations of TIL-based Immunotherapy in Patients With Metastatic CRC and PC

Metastatic Colorectal CancerProstate Cancer MetastaticProstate Cancer Locally Advanced
Curacell Holding AB12 enrolled1 locationNCT07255664
Recruiting
Phase 2

Testing a Functional Precision Medicine Approach to Select Chemotherapy for Metastatic Colorectal Cancer (COSENSE-1)

Metastatic Colorectal CancerFirst-line TreatmentOrganoids+3 more
St. Olavs Hospital148 enrolled1 locationNCT06907342
Recruiting
Phase 1Phase 2

Glumetinib Combined With Fruquintinib in the Treatment of MET Amplification or Protein Overexpression in Third-Line Unresectable Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
Liu Huang42 enrolled1 locationNCT06980532
Recruiting
Phase 2

Regorafenib in Combination With Multimodal Metronomic Chemotherapy for Chemo-resistant Metastatic Colorectal Cancers

Metastatic Colorectal Cancer
Centre Hospitalier Universitaire de Besancon174 enrolled10 locationsNCT06425133
Recruiting
Phase 2

Combination Therapy for BRAF-V600E Metastatic CRCm

Metastatic Colorectal Cancer
Vall d'Hebron Institute of Oncology94 enrolled1 locationNCT06411600
Recruiting
Phase 2

A Phase 2 Study of SSGJ-707 in Metastatic Colorectal Cancer Patients

Metastatic Colorectal Cancer
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.130 enrolled1 locationNCT06493760
Recruiting
Phase 2

FTD-TPI, Bevacizumab, and Radioembolization With 166Ho-microspheres in Refractory Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
UMC Utrecht40 enrolled1 locationNCT06563986
Recruiting
Phase 2

ctDNA-guided Treatment of TKI Plus PD-1 Inhibitor for Advanced pMMR/MSS Colorectal Cancer

Metastatic Colorectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences68 enrolled1 locationNCT06543836
Recruiting
Phase 2

Efficacy and Safety of Trifluridine/Tipiracil Combined With Fufuquitinib for Third-line Treatment of mCRC

Metastatic Colorectal CancerDrug Therapy
First Affiliated Hospital of Wenzhou Medical University200 enrolled1 locationNCT06485713
Recruiting
Phase 2

Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
Dominik Paul Modest153 enrolled1 locationNCT05007132
Recruiting
Phase 2

Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer

Metastatic Colorectal Cancer
Oslo University Hospital40 enrolled1 locationNCT05725200