Phase 3 Metastatic Colorectal Cancer Clinical Trials
8 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–8 of 8 trials
Recruiting
Phase 3
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Metastatic Colorectal Cancer
Amgen450 enrolled284 locationsNCT06252649
Recruiting
Phase 3
A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and Tipiracil (LONSURF) Oral Tablets Plus IV Infused Bevacizumab in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
AbbVie460 enrolled51 locationsNCT06614192
Recruiting
Phase 2Phase 3
Regorafenib With Low-dose Chemotherapies and Aspirin Followed by Standard Chemotherapies in Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Centre Hospitalier Universitaire de Besancon446 enrolled16 locationsNCT05462613
Recruiting
Phase 2Phase 3
A Clinical Study to Evaluate Efficacy and Safety of Serplulimab（HLX10） Combined With Bevacizumab（HLX04) and Chemotherapy (XELOX) in Patients With Metastatic Colorectal Cancer (mCRC)
Metastatic Colorectal Cancer
Shanghai Henlius Biotech568 enrolled5 locationsNCT04547166
Recruiting
Phase 2Phase 3
Sacituzumab Govitecan in Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
University Hospital Heidelberg80 enrolled1 locationNCT06243393
Recruiting
Phase 3
A Study of Systemic Chemotherapy With/Without HAI in Patients With Initially Unresectable Colorectal Liver Metastasis
Metastatic Colorectal Cancer
Yuhong Li142 enrolled1 locationNCT02102789
Recruiting
Phase 3
Sulfasalazine in Patients With Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Tanta University50 enrolled1 locationNCT06134388
Recruiting
Phase 3
Nitazoxanide in Patients With Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Tanta University60 enrolled1 locationNCT06049901