Phase 3 Metastatic Disease Clinical Trials

7 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 17 of 7 trials

Recruiting
Phase 2Phase 3

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

OligoProgressive Metastatic Disease
M.D. Anderson Cancer Center400 enrolled1 locationNCT06367972
Recruiting
Phase 3

Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC

Oligometastatic DiseaseMetastatic Non Small Cell Lung Cancer
Tata Memorial Hospital190 enrolled1 locationNCT05278052
Recruiting
Phase 3

Continuation of First-line Therapy With Radiotherapy Versus Early Switch to Second-line Therapy in Oligoprogressive HCC

RadiotherapyOligoProgressive Metastatic DiseaseHepatocellular Carcinoma (HCC)+1 more
Shandong Cancer Hospital and Institute132 enrolled1 locationNCT06841172
Recruiting
Phase 3

Stereotactic Body Radiotherapy for Oligo-Progression Metastatic Non-Small Cell Lung Cancer

OligoProgressive Metastatic DiseaseNSCLC Stage IVMetastatic Non Small Cell Lung Cancer
Second Affiliated Hospital, School of Medicine, Zhejiang University104 enrolled1 locationNCT06523673
Recruiting
Phase 2Phase 3

Stereotactic Radiotherapy for Oligometastasis (1-5) in Various Tumor Sites vs. Palliative Care

Oligometastatic Disease
National Medical Research Radiological Centre of the Ministry of Health of Russia100 enrolled1 locationNCT06556550
Recruiting
Phase 3

Metastasis-directed Therapy for Oligorecurrent Prostate Cancer

Prostate CancerMetastatic CancerProstate Cancer Metastatic+4 more
Universitaire Ziekenhuizen KU Leuven873 enrolled1 locationNCT05352178
Recruiting
Phase 3

Local Therapy for Oligometastatic ESCC Patients Treated With PD-1 Inhibitor

Esophageal Squamous Cell CarcinomaOligometastatic DiseaseRadiotherapy
Fudan University354 enrolled1 locationNCT06190782