Phase 2 Metastatic Disease Clinical Trials
21 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 21 trials
Recruiting
Phase 2
Niraparib Rechallenge After Surgery in Ovarian Cancer Patients With Oligometastatic Progression
Ovarian CancerOligometastatic DiseaseSerous Ovarian Tumor
MedSIR30 enrolled14 locationsNCT06180356
Recruiting
Phase 2
Exploration of Treatment Effect of Novel Hormone Therapy Combined With Local Treatment Based on PSMA PET/CT Evaluation in mHSCP Patients
Prostate Cancer Metastatic Disease
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine192 enrolled1 locationNCT06832774
Recruiting
Phase 1Phase 2
Dual-Targeting CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally Advanced or Metastatic Disease
Beijing Biotech42 enrolled1 locationNCT07480928
Recruiting
Phase 2
Proof-of-Concept Trial to Assess the Efficacy and Safety of Fezolinetant in Improving Vasomotor Symptoms in Men With Prostate Cancer Undergoing Androgen Deprivation Therapy
Prostate CancerProstate CarcinomaProstate Neoplasm+12 more
Shehzad Basaria, M.D.60 enrolled1 locationNCT06957691
Recruiting
Phase 2
Using FAPI PET/MRI to Evaluate Prostate Cancer
Prostate CancersProstate Cancer Metastatic Disease
University of Wisconsin, Madison30 enrolled1 locationNCT06675357
Recruiting
Phase 2
Phase II Trial to Investigate the Safety and Efficacy of Four Dosing Regimens of OTL78 Injection
Prostate Cancer SurgeryProstate Cancer Metastatic Disease
Clinton Bahler22 enrolled3 locationsNCT06849544
Recruiting
Phase 1Phase 2
Lymphocyte Support to SBRT in Patients With Oligo-metastatic Solid Cancer
Solid Tumor, AdultOligometastatic Disease
Gustave Roussy, Cancer Campus, Grand Paris58 enrolled2 locationsNCT06439888
Recruiting
Phase 2Phase 3
A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)
OligoProgressive Metastatic Disease
M.D. Anderson Cancer Center400 enrolled1 locationNCT06367972
Recruiting
Phase 2
TERPS Trial for de Novo Oligometastic Prostate Cancer
Prostate CancerOligometastatic Disease
University of Maryland, Baltimore122 enrolled9 locationsNCT05223803
Recruiting
Phase 1Phase 2
A Study of HLD-0915 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)
Prostate Cancer (Adenocarcinoma)Prostate Cancer Metastatic Disease
Halda Therapeutics OpCo, Inc.33 enrolled11 locationsNCT06800313
Recruiting
Phase 2
Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC
Non-small Cell Lung CancerOligometastatic DiseaseDriver Mutation
Tata Memorial Hospital106 enrolled1 locationNCT05277844
Recruiting
Phase 2
Stereotactic Body Radiotherapy or Standard of Care for Prostate Oligoprogressive Cancer
OligoProgressive Metastatic DiseaseCastrate Resistance Prostate Cancer
University Health Network, Toronto75 enrolled1 locationNCT06927635
Recruiting
Phase 2
The Impact of Metastatic Directed Radiotherapy (MDRT) on Oligoprogressive Castration Resistant Prostate Cancer (CRPC)
RadiotherapyOligoProgressive Metastatic DiseaseProstate Cancer (Adenocarcinoma)+1 more
University Medical Center Groningen35 enrolled2 locationsNCT07038304
Recruiting
Phase 2
Radiotherapy or Surgery Combined With Intense Androgen Deprivation Therapy for mCRPC
Prostate Cancer Metastatic Disease
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School144 enrolled1 locationNCT06992232
Recruiting
Phase 2
High-Risk Metachronous Oligometastatic Prostate Cancer Trial
Prostate CancerOligometastatic Disease
University of Maryland, Baltimore88 enrolled1 locationNCT06212583
Recruiting
Phase 2
OLIGO-10: Stereotactic Ablative Radiation Therapy for Metastatic Patients With 6 to 10 Metastatic Sites
Metastatic Disease
National Medical Research Radiological Centre of the Ministry of Health of Russia50 enrolled1 locationNCT06856603
Recruiting
Phase 2Phase 3
Stereotactic Radiotherapy for Oligometastasis (1-5) in Various Tumor Sites vs. Palliative Care
Oligometastatic Disease
National Medical Research Radiological Centre of the Ministry of Health of Russia100 enrolled1 locationNCT06556550
Recruiting
Phase 2
Consolidative Radiotherapy Combined With Camrelizumab and Chemotherapy for Oligometastatic Nasopharyngeal Carcinoma
Oligometastatic Disease
Jiangxi Provincial Cancer Hospital63 enrolled3 locationsNCT05128201
Recruiting
Phase 2
Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
Gastroesophageal-junction CancerGastroesophageal Junction AdenocarcinomaMetastatic Cancer+6 more
Fudan University55 enrolled1 locationNCT06121700
Recruiting
Phase 2
Phase 2 Study of SBRT Plus Tislelizumab and Regorafenib in Unresectable or Oligometastatic HCC
Unresectable Hepatocellular CarcinomaOligometastatic Disease
Peking University Cancer Hospital & Institute39 enrolled1 locationNCT05917431