Phase 2 Metastatic Pancreatic Ductal Adenocarcinoma Clinical Trials
12 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–12 of 12 trials
Recruiting
Phase 2Phase 3
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Metastatic Pancreatic Ductal AdenocarcinomaPDAC
AbbVie900 enrolled11 locationsNCT07490301
Recruiting
Phase 2Phase 3
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
Metastatic Pancreatic Ductal AdenocarcinomaCachexia
Pfizer982 enrolled188 locationsNCT06989437
Recruiting
Phase 1Phase 2
Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
Stage IV Pancreatic Cancer AJCC v8Metastatic Pancreatic Ductal Adenocarcinoma
Roswell Park Cancer Institute35 enrolled1 locationNCT07214298
Recruiting
Phase 1Phase 2
ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma
Metastatic Pancreatic Ductal Adenocarcinoma
Washington University School of Medicine61 enrolled1 locationNCT06904378
Recruiting
Phase 1Phase 2
The KN510713 Study in Combination With mFOLFIRINOX
Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
New Cancer Cure-Bio Co.,Ltd.30 enrolled1 locationNCT07114861
Recruiting
Phase 1Phase 2
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Colorectal, CancerPancreatic Ductal AdenocarcinomaMetastatic Pancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc.1,130 enrolled32 locationsNCT06445062
Recruiting
Phase 2
PULSAR in Systemic Therapy for Pancreatic Cancer
Borderline Resectable Pancreatic Ductal AdenocarcinomaLocally Advanced Pancreatic Ductal AdenocarcinomaOligometastatic Pancreatic Ductal Adenocarcinoma
Samsung Medical Center47 enrolled1 locationNCT07269626
Recruiting
Phase 2
Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal AdenocarcinomaMetastatic Pancreatic Ductal Adenocarcinoma
University of Miami50 enrolled1 locationNCT07096362
Recruiting
Phase 2
The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation
Metastatic Pancreatic CancerMetastatic Pancreatic Ductal Adenocarcinoma
Benjamin Spieler20 enrolled1 locationNCT06843551
Recruiting
Phase 2
A Study Evaluating the Efficacy of 5-FU + NALIRI and 5-FU + NALIRINOX for PDAC (NALPAC)
Metastatic Pancreatic Ductal Adenocarcinoma
Belgian Group of Digestive Oncology134 enrolled13 locationsNCT05472259
Completed
Phase 2
A Randomised, Double-blinded Phase II Study of Gemcitabine and Nab-Paclitaxel with CEND-1/LSTA1 (Certepetide) or Placebo in Patients with Untreated Metastatic Pancreatic Ductal Adenocarcinoma
Metastatic Pancreatic Ductal Adenocarcinoma
Australasian Gastro-Intestinal Cancer Trials Group155 enrolled24 locationsACTRN12621001290886
Suspended
Phase 2
Panitumumab as second line therapy for advanced pancreatic ductal adenocarcinoma with wild-type KRAS gene
KRAS wild-type unresectable or metastatic pancreatic ductal adenocarcinoma
Dr Daniel Croagh24 enrolled1 locationACTRN12617000540314