Phase 2 MF Clinical Trials
22 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 22 trials
Recruiting
Phase 2
A Clinical Trial of Flonoltinib Maleate Tablets in the Treatment of JAK Inhibitor Refractory/Relapsed/Intolerant Patients With Medium to High Risk Myelofibrosis
MF
Chengdu Zenitar Biomedical Technology Co., Ltd64 enrolled2 locationsNCT07443306
Recruiting
Phase 2
Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)
Myelofibrosis (PMF)Post Essential Thrombocythemia Myelofibrosis (ET-MF)Post Polycythemia Vera Related Myelofibrosis (PV-MF)
Icahn School of Medicine at Mount Sinai10 enrolled9 locationsNCT05835466
Recruiting
Phase 2
Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have Thrombocytopenia
Myelofibrosis (MF)
Grupo Español de Enfermedades Mieloproliferativas Crónicas PH Negativas30 enrolled13 locationsNCT07394153
Recruiting
Phase 1Phase 2
A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors
Myelofibrosis (MF)
iOnctura26 enrolled11 locationsNCT06887803
Recruiting
Phase 1Phase 2
Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT
LeukemiaInborn Errors of MetabolismHLH+11 more
Children's Hospital of Philadelphia100 enrolled1 locationNCT06839456
Recruiting
Phase 2
Study of Canakinumab in Patients With Myelofibrosis
Primary MyelofibrosisPost-essential Thrombocythemia MyelofibrosisET-MF+2 more
John Mascarenhas14 enrolled8 locationsNCT05467800
Recruiting
Phase 2
Hypofractionated, 3-week, Preoperative Proton or X-ray Radiotherapy for Patients With Localized Soft Tissue Sarcoma
Soft Tissue Sarcoma AdultLeiomyosarcomaSynovial Sarcomas+6 more
Oslo University Hospital110 enrolled4 locationsNCT07169344
Recruiting
Phase 1Phase 2
A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors
Ovarian CarcinomaNSCLCSCLC+5 more
Jacobio Pharmaceuticals Co., Ltd.152 enrolled1 locationNCT04686682
Recruiting
Phase 1Phase 2
Phase I/II Clinical Trial of Axatilimab, a CSF1R Monoclonal Antibody, in Combination With Ruxolitinib as Therapy for Patients With Myelofibrosis (MF) and Chronic Myelomonocytic Leukemia (CMML)
Chronic Myelomonocytic Leukemia (CMML)Myelofibrosis (MF)
M.D. Anderson Cancer Center66 enrolled1 locationNCT07128381
Not Yet Recruiting
Phase 2
Safety Study to Evaluate Gastrointestinal Adverse Events of Azurity Cabozantinib Tablets vs. CABOMETYX® Tablets in Advanced or Metastatic Renal Cell Carcinoma Patients
Gastrointestinal Discomfort
Azurity Pharmaceuticals, Inc.45 enrolled1 locationACTRN12625001422415
Recruiting
Phase 2
MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial
Myelofibrosis (MF)Essential Thrombocythemia, ETPolycythemia Vera (PV)
Icahn School of Medicine at Mount Sinai54 enrolled1 locationNCT06541249
Recruiting
Phase 2
Ropeginterferon Alfa 2b Plus Ruxolitinib for Myelofibrosis
Primary myelofibrosis (PMF)Post Polycythemia Myelofibrosis (PPV MF)Post Essential Thrombocythaemia Myelofibrosis (PET-MF)
The University of Hong Kong20 enrolled1 locationNCT06770842
Recruiting
Phase 2
A Phase II Clinical Trial of Flonoltinib Maleate Tablet in Intermediate-High Risk Myelofibrosis
MF,PMF,PPV-MF,PET-MF
Chengdu Zenitar Biomedical Technology Co., Ltd75 enrolled2 locationsNCT06457425
Recruiting
Phase 2
The Efficacy and Safety of Desensitation Regimen for Patients With High Titers of Anti-HLA Antibodies Prior to Allo-HSCT
High Titers of Anti-HLA Antibody (MFI ≥5000)
Anhui Provincial Hospital30 enrolled1 locationNCT06362967
Recruiting
Phase 2
Safety and Efficacy of RPH-104 Used to Prevent Recurrent Fever Attacks in Adult Patients With Colchicine Resistant or Colchicine Intolerant Familial Mediterranean Fever
FMFFamilial Mediterranean Fever
R-Pharm International, LLC60 enrolled8 locationsNCT05190991
Recruiting
Phase 1Phase 2
Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib
MyelofibrosisPrimary MyelofibrosisPost-PV MF+1 more
Telios Pharma, Inc.70 enrolled19 locationsNCT05280509
Completed
Phase 2
A practice based trial of a combination of nutritional interventions: probiotics, glutamine and fish oils in patients experiencing psychological distress.
Mild digestive discomfort
Southern Cross University10 enrolled1 locationACTRN12620000928910
Completed
Phase 2
Anti-inflammatory treatments for contact lens discomfort
Contact lens discomfort
The University of Melbourne80 enrolled1 locationACTRN12615000173594
Completed
Phase 2
Effect of a new orthosis on pain and mechanical forces in prone position in women with augmented or natural breast tissue
Orthosis in women with augmented or natural breast tissue in prone position who experience breast discomfort
National Institute of Integrative Medicine30 enrolled1 locationACTRN12613000541707
Recruiting
Phase 2
Evaluation of Anxiolysis and Pain Associated with Retrobulbar Eye Block for Cataract Surgery : Melatonin versus Gabapentin ( A randomized, double-blind, placebo-controlled study)
Tolerance of retrobulbar injection
and comfort during the surgical procedureanxiety during performance retrobulbar block and cataract surgerypain during performance retrobulbar block and cataract surgery
Qazvin university of medical science90 enrolled1 locationACTRN12610000727044