Migraine Without Aura Clinical Trials

9 recruitingLast updated: May 5, 2026

There are 9 actively recruiting migraine without aura clinical trials across 5 countries. Studies span Not Applicable, Phase 3. Top locations include Florence, Italy, Pavia, Italy, Cincinnati, Ohio, United States. Updated daily from ClinicalTrials.gov.


Migraine Without Aura Trials at a Glance

9 actively recruiting trials for migraine without aura are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Florence, Pavia, and Cincinnati. Lead sponsors running migraine without aura studies include University of Florence, Children's Hospital Medical Center, Cincinnati, and Fundación de Investigación Biomédica - Hospital Universitario de La Princesa.

Browse migraine without aura trials by phase

Treatments under study

About Migraine Without Aura Clinical Trials

Looking for clinical trials for Migraine Without Aura? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Migraine Without Aura trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Migraine Without Aura clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Not Applicable

Trial Designs for Evaluating Migraine Treatment

Migraine with auraHeadache, MigraineMigraine Without Aura
University of Aarhus128 enrolled2 locationsNCT06617832
Recruiting
Not Applicable

Mind Body Balance for Pediatric Migraine

Migraine with auraMigraineChronic Migraine+5 more
Children's Hospital Medical Center, Cincinnati260 enrolled2 locationsNCT04715685
Recruiting
Not Applicable

Responding With Evidence and Access for Childhood Headaches

Migraine with auraMigraineChronic Migraine+5 more
Children's Hospital Medical Center, Cincinnati400 enrolled15 locationsNCT05889624
Recruiting

RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment

Migraine with auraMigraineChronic Migraine+1 more
University of Florence100 enrolled2 locationsNCT06409832
Recruiting

Gepant treAtments: EffectIveNess and tolERability (GAINER)

Migraine with auraMigraineChronic Migraine+1 more
University of Florence100 enrolled2 locationsNCT05903027
Recruiting

Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification

migraine headacheMigraine with auraMigraine+5 more
Hospital Universitari Vall d'Hebron Research Institute440 enrolled1 locationNCT06674772
Recruiting
Phase 3

TIzanidine for the Preventive Treatment of Episodic MigrainE (TIME)

Migraine Without Aura
Second Affiliated Hospital, School of Medicine, Zhejiang University189 enrolled6 locationsNCT05484349
Recruiting

Migraine Attack Pain Phase Prediction Study

migraine headacheMigraine with auraMigraine+2 more
Fundación de Investigación Biomédica - Hospital Universitario de La Princesa70 enrolled1 locationNCT06459635
Recruiting

Effectiveness and Tolerability of Eptinezumab

Migraine with auraMigraineChronic Migraine+1 more
University of Florence100 enrolled2 locationsNCT06409845