Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification
Fenotipado Molecular De Pacientes Con Migraña Según Edad Y Sexo a Través De La Cuantificación De CGRP En Saliva Para Realizar Medicina De Precisión: Estudio FAST
Hospital Universitari Vall d'Hebron Research Institute
440 participants
Nov 29, 2022
OBSERVATIONAL
Conditions
Summary
Patients will be asked to visit the study center 2 times, the first time for clinical assessment and a second time for sample collection. Healthy controls will only be asked to visit the study center for sample collection. A sample of blood and saliva will be collected in order to measure CGRP levels and DNA and hormone testing.
Eligibility
Inclusion Criteria2
- Migraine patients according to ICHD-3 criteria
- Healthy controls paired to patient age and sex, without headache and without first degree family history of headache.
Exclusion Criteria5
- Presence of any major medical or neurological illness.
- Presence of any salivary gland malfunction.
- Abuse or dependence to tobacco, alcohol or any drug in the previous 12 months before the enrollment.
- Active migraine preventive treatment.
- Pregnant or breastfeeding female.
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Interventions
Sampling of CGRP in saliva and DNA blood test and sex hormones blood test.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06674772