Early Phase 1 MS Clinical Trials
26 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 26 trials
Recruiting
Early Phase 1
Evaluation of [¹⁸F]MODAG-009 PET Imaging in Synucleinopathies
Parkinson DiseaseHealthy AdultMultiple System Atrophy (MSA)
MODAG GmbH13 enrolled1 locationNCT07640555
Recruiting
Early Phase 1
CAR 70-BCMA CAR-T Cells for the Treatment of Relapsed or Refractory Plasma Cell Neoplasms
Relapsed or Refractory Plasma Cell Neoplasms
The General Hospital of Western Theater Command20 enrolled1 locationNCT07519187
Recruiting
Early Phase 1
Botensilimab, Balstilimab, and SBRT in Colorectal Cancer
Non-MSI-H or pMMR Colorectal Cancer With Liver Metastasis
Massachusetts General Hospital15 enrolled1 locationNCT07128355
Recruiting
Early Phase 1
CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases
Relapsing or Refractory Multiple Sclerosis (MS)Myasthenia Gravis (MG)Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)+1 more
Tongji Hospital36 enrolled1 locationNCT07337785
Recruiting
Early Phase 1
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting
Early Phase 1
Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
Breast CancerAromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)Joint Pain
Philip Chang30 enrolled2 locationsNCT06123286
Recruiting
Early Phase 1
Pencil Beam Scanning in Patients With Renal Tumors
Wilms TumorRenal Tumor
Children's Hospital of Philadelphia28 enrolled1 locationNCT03810651
Recruiting
Early Phase 1
Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia
Myelodysplastic SyndromesChronic Myelomonocytic LeukemiaMyeloproliferative Overlap Neoplasms+1 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins18 enrolled1 locationNCT07071155
Recruiting
Early Phase 1
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Early Phase 1
177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors
Endometrial CancerNon-small Cell Lung CancerTNBC - Triple-Negative Breast Cancer+6 more
Radiopharm Theranostics, Ltd30 enrolled5 locationsNCT06305962
Recruiting
Early Phase 1
Effects of Ublituximab on Motor Functions in Multiple Sclerosis
Multiple Sclerosis (MS) - Relapsing-remitting
Georgia State University25 enrolled2 locationsNCT06629428
Recruiting
Early Phase 1
In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET
Non-Hodgkin LymphomaMultiple MyelomaErdheim-Chester Disease+2 more
Memorial Sloan Kettering Cancer Center30 enrolled1 locationNCT05093335
Recruiting
Early Phase 1
Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases
SLESystemic SclerosisNMOSD+4 more
Nanjing Bioheng Biotech Co., Ltd.18 enrolled1 locationNCT06775912
Recruiting
Early Phase 1
Virtual Histology of the Bladder Wall for Bladder Cancer Staging
Urinary Bladder Neoplasms
Jodi Maranchie42 enrolled1 locationNCT04369560
Recruiting
Early Phase 1
[18F]ACI-15916 PET in α-synucleinopathies
Parkinson's Disease (PD)Multiple System Atrophy (MSA)Dementia With Lewy Bodies (DLB)
AC Immune SA46 enrolled1 locationNCT06891703
Recruiting
Early Phase 1
The Study of Safety and Preliminary Efficacy of Aleeto in Patients With MultIple System Atrophy
Multiple System Atrophy (MSA)Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
Beijing Tiantan Hospital20 enrolled1 locationNCT06765733
Recruiting
Early Phase 1
A Molecular Probe Targeting BCMA for the Clinical Diagnosis of Multiple Myeloma
Multiple Myeloma and Malignant Plasma Cell Neoplasms
Peking University First Hospital50 enrolled2 locationsNCT06717113
Recruiting
Early Phase 1
Study of KRAS Neoantigen mRNA Vaccine (ABO2102) in Patients With KRAS -Mutated Solid Tumors
Pancreatic NeoplasmsOther Solid Tumors
Ruijin Hospital56 enrolled1 locationNCT06577532
Recruiting
Early Phase 1
Safety and Efficacy of Intravenous IDOV-SAFETM in Patients With Advanced Solid Tumors
Neoplasms
Cancer Institute and Hospital, Chinese Academy of Medical Sciences19 enrolled1 locationNCT06346041
Recruiting
Early Phase 1
Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System
Myasthenia GravisAutoimmune EncephalitisMultiple Sclerosis+7 more
Tongji Hospital36 enrolled1 locationNCT04561557