Early Phase 1 MS Clinical Trials
22 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–20 of 22 trials
Recruiting
Early Phase 1
Pencil Beam Scanning in Patients With Renal Tumors
Wilms TumorRenal Tumor
Children's Hospital of Philadelphia28 enrolled1 locationNCT03810651
Recruiting
Early Phase 1
Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia
Myelodysplastic SyndromesChronic Myelomonocytic LeukemiaMyeloproliferative Overlap Neoplasms+1 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins18 enrolled1 locationNCT07071155
Recruiting
Early Phase 1
Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease
DepressionDepressive SymptomsAlzheimer Disease+1 more
Johns Hopkins University20 enrolled1 locationNCT04123314
Recruiting
Early Phase 1
Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms
Breast CancerAromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS)Joint Pain
Philip Chang30 enrolled2 locationsNCT06123286
Recruiting
Early Phase 1
Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease
Alzheimer DiseaseMild Cognitive ImpairmentLogopenic Progressive Aphasia+1 more
Massachusetts General Hospital30 enrolled1 locationNCT06538311
Recruiting
Early Phase 1
Effects of Ublituximab on Motor Functions in Multiple Sclerosis
Multiple Sclerosis (MS) - Relapsing-remitting
Georgia State University25 enrolled2 locationsNCT06629428
Recruiting
Early Phase 1
In-Human CXCR4 Imaging of Hematologic and Solid Tumors Using [68Ga]-Pentixafor-PET
Non-Hodgkin LymphomaMultiple MyelomaErdheim-Chester Disease+1 more
Memorial Sloan Kettering Cancer Center30 enrolled1 locationNCT05093335
Recruiting
Early Phase 1
Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases
SLESystemic SclerosisNMOSD+4 more
Nanjing Bioheng Biotech Co., Ltd.18 enrolled1 locationNCT06775912
Recruiting
Early Phase 1
CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases
Relapsing or Refractory Multiple Sclerosis (MS)Myasthenia Gravis (MG)Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)+1 more
Daishi Tian36 enrolled1 locationNCT07337785
Recruiting
Early Phase 1
Virtual Histology of the Bladder Wall for Bladder Cancer Staging
Urinary Bladder Neoplasms
Jodi Maranchie42 enrolled1 locationNCT04369560
Recruiting
Early Phase 1
[18F]ACI-15916 PET in α-synucleinopathies
Parkinson's Disease (PD)Multiple System Atrophy (MSA)Dementia With Lewy Bodies (DLB)
AC Immune SA46 enrolled1 locationNCT06891703
Recruiting
Early Phase 1
The Study of Safety and Preliminary Efficacy of Aleeto in Patients With MultIple System Atrophy
Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
Beijing Tiantan Hospital20 enrolled1 locationNCT06765733
Recruiting
Early Phase 1
A Molecular Probe Targeting BCMA for the Clinical Diagnosis of Multiple Myeloma
Multiple Myeloma and Malignant Plasma Cell Neoplasms
Peking University First Hospital50 enrolled2 locationsNCT06717113
Recruiting
Early Phase 1
Study of KRAS Neoantigen mRNA Vaccine (ABO2102) in Patients With KRAS -Mutated Solid Tumors
Pancreatic NeoplasmsOther Solid Tumors
Ruijin Hospital56 enrolled1 locationNCT06577532
Recruiting
Early Phase 1
Safety and Efficacy of Intravenous IDOV-SAFETM in Patients With Advanced Solid Tumors
Neoplasms
Cancer Institute and Hospital, Chinese Academy of Medical Sciences19 enrolled1 locationNCT06346041
Recruiting
Early Phase 1
Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System
Myasthenia GravisAutoimmune EncephalitisMultiple Sclerosis+7 more
Tongji Hospital36 enrolled1 locationNCT04561557
Recruiting
Early Phase 1
68Ga-FAPI-RGD PET/CT Imaging in the Lung Cancer Patients
Lung Neoplasms
Peking Union Medical College Hospital60 enrolled1 locationNCT05543954
Recruiting
Early Phase 1
Pilot Study of Neoantigen Peptides and Leukine for the Treatment of Neoplasms
Neoplasms
Instituto de Medicina Regenerativa100 enrolled1 locationNCT05475106
Recruiting
Early Phase 1
A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer
Esophageal CancerHead and Neck CancerLaryngeal Cancer+4 more
Shanghai Yunying Medical Technology9 enrolled1 locationNCT05830240
Completed
Early Phase 1
The buccal administration of a NanoCelle™ Cannabidiol formulation to healthy volunteers: a pharmacokinetic, safety and tolerability exploratory pilot study.
The Investigational Product may be indicated for insomniaThe Investigational Product may be indicated for the treatment of inflammatory painThe Investigational Product may be indicated for mood symptoms+1 more
Medlab Clinical16 enrolled1 locationACTRN12617001491358