Myalgic Encephalomyelitis Clinical Trials

12 recruitingLast updated: June 18, 2026

There are 12 actively recruiting myalgic encephalomyelitis clinical trials across 5 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3. Top locations include New York, New York, United States, Bethesda, Maryland, United States, Calgary, Alberta, Canada. Updated daily from ClinicalTrials.gov.


Myalgic Encephalomyelitis Trials at a Glance

12 actively recruiting trials for myalgic encephalomyelitis are listed on ClinicalTrialsFinder across 6 cities in 5 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in New York, Bethesda, and Calgary. Lead sponsors running myalgic encephalomyelitis studies include Charite University, Berlin, Germany, Deakin University, and Brain Inflammation Collaborative.

Browse myalgic encephalomyelitis trials by phase

Treatments under study

About Myalgic Encephalomyelitis Clinical Trials

Looking for clinical trials for Myalgic Encephalomyelitis? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Myalgic Encephalomyelitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Myalgic Encephalomyelitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting

Patient-Centered Assessment of Symptoms and Outcomes

Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCancerFatigue+5 more
National Center for Complementary and Integrative Health (NCCIH)692 enrolled1 locationNCT03952624
Recruiting
Not Applicable

RCT of Mind-body in Long COVID and Myalgic Encephalomyelitis

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
University of Alberta200 enrolled3 locationsNCT06933173
Recruiting

Observational Study on Immunoadsorption (IA) in Patients With Autoantibody-Positive Post-Infectious ME/CFS

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)ME/CFS Following COVID-19
Charite University, Berlin, Germany50 enrolled1 locationNCT07529197
Recruiting
Phase 1Phase 2

Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Myalgic EncephalomyelitisChronic Fatigue SyndromePost-treatment Lyme Disease Syndrome+1 more
Icahn School of Medicine at Mount Sinai120 enrolled1 locationNCT06511050
Recruiting

Chronic Infections and Inflammation in ME/CFS: An Observational Study

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
University of California, San Francisco200 enrolled1 locationNCT07227441
Recruiting
Phase 2

Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Myalgic EncephalomyelitisChronic Fatigue Syndrome
Weill Medical College of Cornell University95 enrolled1 locationNCT04542161
Recruiting

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Traumatic Brain InjuryEhlers-Danlos SyndromePost-Acute COVID-19 Syndrome+41 more
Brain Inflammation Collaborative10,000 enrolled1 locationNCT04806620
Recruiting
Not Applicable

A 3-day Course for CFS/ME

Myalgic EncephalomyelitisChronic Fatigue Syndrome
Norwegian University of Science and Technology100 enrolled1 locationNCT05236465
Recruiting
Not Applicable

The Long COVID-19 Wearable Device Study

Postural Orthostatic tachycardia SyndromeMyalgic EncephalomyelitisChronic Fatigue Syndrome+3 more
Scripps Translational Science Institute100,500 enrolled1 locationNCT05741112
Recruiting
Phase 2Phase 3

TRI-ME: Trimetazidine to treat Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A double-blind, randomised, placebo-controlled efficacy trial

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Deakin University126 enrolled1 locationACTRN12625000095460
Recruiting

FUNCAP-27 (Functional Capacity), A Repeat Measure Study (FARMS), A survey to establish the utility of the FUNCAP-27 for serial measurements in Myalgic Encephalomyelitis, Chronic Fatigue Syndrome (ME/CFS) and Long Covid

ME/CFS (Myalgic Encephalomyelitis / Chronic Fatigue Syndrome)
The University of Melbourne1,000 enrolled1 locationACTRN12624001479594
Recruiting

Munich ME/CFS Cohort Study

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
Technical University of Munich200 enrolled1 locationNCT06005246