Necrosis Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Necrosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 53 trials

Recruiting
Not Applicable

Marrow Cellution™ vs. Traditional BMA Harvest Project

Hip ArthropathyAvascular Necrosis of BoneSubchondral Cysts
Ohio State University6 enrolled1 locationNCT06388993
Recruiting
Not Applicable

Contribution of the CEST Sequence in the Characterization of Radionecrosis of Brain Metastases of Pulmonary Origin

Brain MetastasesPulmonary CancerRadionecrosis
Assistance Publique - Hôpitaux de Paris60 enrolled1 locationNCT05977803
Recruiting

Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty

Hip ReplacementFemur Head NecrosisPrimary, Secondary or Post-traumatic Osteoarthrosis+2 more
Corin2,500 enrolled13 locationsNCT02230826
Recruiting

Observational Study to Evaluate Long-Term Outcome in Hip Hemiarthroplasty

Hip FracturesOsteoarthritis, HipAvascular Necrosis of Hip+2 more
Corin368 enrolled4 locationsNCT05686278
Recruiting
Not Applicable

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Rheumatoid ArthritisOsteoarthritisTraumatic Arthritis+3 more
DePuy Orthopaedics118 enrolled5 locationsNCT06631638
Recruiting
Phase 4

Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)

Hip FracturesFemoral Neck FracturesFemur Head Necrosis
Huazhong University of Science and Technology60 enrolled1 locationNCT06565910
Recruiting

Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France

Pulpitis - IrreversiblePulp Necrosis
University Hospital, Strasbourg, France100 enrolled1 locationNCT07297836
Recruiting
Not Applicable

Necrosectomy With Cryotechnology for Accelerated Removal

Acute PancreatitisPancreatic NecrosisAcute Pancreatic Necrosis+3 more
Christopher C. Thompson, MD, MSc20 enrolled1 locationNCT06553651
Recruiting
Phase 3

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting

Perform Humeral System Study

Osteoarthritis ShoulderRotator Cuff Tear ArthropathyAvascular Necrosis+1 more
Stryker Trauma and Extremities300 enrolled10 locationsNCT05067543
Recruiting
Not Applicable

REMASTer: REcurrent Brain Metastases After SRS Trial

Brain MetastasesRadiation NecrosisRecurrent Tumor+1 more
Monteris Medical261 enrolled9 locationsNCT05124912
Recruiting
Not Applicable

Development of MRF for Characterization of Brain Tumors After Radiotherapy

Brain MetastasesBrain TumorGlioma+1 more
Case Comprehensive Cancer Center60 enrolled2 locationsNCT06101069
Recruiting
Phase 2

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

Sickle Cell DiseaseOsteonecrosisAvascular Necrosis+2 more
University of California, Davis30 enrolled1 locationNCT06016634
Recruiting

Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)

Rheumatoid ArthritisOsteoarthritis, KneePolyarthritis+6 more
Zimmer Biomet760 enrolled16 locationsNCT05787821
Recruiting

Prospective Registry Of Therapeutic EndoscopiC ulTrasound

Chronic PancreatitisGastric Outlet ObstructionAcute Pancreatic Fluid Collection+3 more
Paolo Giorgio Arcidiacono, MD510 enrolled1 locationNCT04813055
Recruiting

Exactech Shoulder Post Market Clinical Follow-up Study

Rheumatoid ArthritisInfectionsAnkylosing Spondylitis+6 more
Exactech20,000 enrolled38 locationsNCT05603728
Recruiting
Not Applicable

Safety and Effectiveness of the HIT Reverse HRS

Degenerative Joint DiseaseOsteoarthritis, HipAvascular Necrosis of Hip+1 more
Hip Innovation Technology288 enrolled6 locationsNCT05357378
Recruiting
Not Applicable

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

Osteonecrosis of the Femoral HeadAvascular Necrosis of the Femoral Head
Johns Hopkins University192 enrolled10 locationsNCT06123481
Recruiting
Phase 4

Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

OsteoradionecrosisMalignant Oral Cavity NeoplasmMalignant Skull Base Neoplasm
M.D. Anderson Cancer Center425 enrolled1 locationNCT04265430
Recruiting

Registry of Patients Undergoing Endoscopic Management of Pancreatic Fluid Collections

Acute PancreatitisPancreatic PseudocystPancreatic Necrosis
Orlando Health, Inc.1,000 enrolled1 locationNCT06179459