Necrosis Clinical Trials

70 recruitingLast updated: May 13, 2026

There are 70 actively recruiting necrosis clinical trials across 27 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4. Top locations include Paris, France, Baltimore, Maryland, United States, Cleveland, Ohio, United States. Updated daily from ClinicalTrials.gov.


Necrosis Trials at a Glance

70 actively recruiting trials for necrosis are listed on ClinicalTrialsFinder across 6 cities in 27 countries. The largest study group is Not Applicable with 28 trials, with the heaviest enrollment activity in Paris, Baltimore, and Cleveland. Lead sponsors running necrosis studies include Medacta International SA, Zimmer Biomet, and Corin.

Browse necrosis trials by phase

Treatments under study

About Necrosis Clinical Trials

Looking for clinical trials for Necrosis? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Necrosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Necrosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 70 trials

Recruiting
Not Applicable

Safety and Effectiveness of the HIT Reverse HRS

Degenerative Joint DiseaseOsteoarthritis, HipAvascular Necrosis of Hip+1 more
Hip Innovation Technology288 enrolled6 locationsNCT05357378
Recruiting
Not Applicable

EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

Rheumatoid ArthritisOsteoarthritisTraumatic Arthritis+3 more
DePuy Orthopaedics118 enrolled5 locationsNCT06631638
Recruiting
Not Applicable

Development of MRF for Characterization of Brain Tumors After Radiotherapy

Brain MetastasesBrain TumorGlioma+1 more
Case Comprehensive Cancer Center90 enrolled2 locationsNCT06101069
Recruiting
Not Applicable

Clinical Transformation of Bone Reconstruction With Autologous Bone Marrow Mesenchymal Stem Cells in Vitro to Repair Avascular Necrosis of Femur Head

Avascular Necrosis of Femur Head
The First Affiliated Hospital of Xinxiang Medical College30 enrolled1 locationNCT07101562
Recruiting

RETRO-PROSPECTIVE POSTMARKET CLINICAL STUDY FOR FX SHOULDER SOLUTIONS SHOULDER SYSTEMS

Glenohumeral OsteoarthritisAvascular Necrosis of the Head of HumerusInflammatory Arthritis+4 more
FX Solutions1,004 enrolled22 locationsNCT07558590
Recruiting

Talus Replacement Registry

Avascular Necrosis of the Talus
Kyle Schweser MD50 enrolled1 locationNCT03965143
Recruiting

Screening for Biomarkers of Osteonecrosis of the Femoral Head

Osteonecrosis of the Femoral Head
The First Affiliated Hospital of Xinxiang Medical College300 enrolled1 locationNCT07545616
Recruiting

Prospective Registry Of Therapeutic EndoscopiC ulTrasound

Chronic PancreatitisGastric Outlet ObstructionAcute Pancreatic Fluid Collection+3 more
Paolo Giorgio Arcidiacono, MD510 enrolled1 locationNCT04813055
Recruiting
Phase 2

Alendronate for Osteonecrosis in Adults With Sickle Cell Disease

Sickle Cell DiseaseOsteonecrosisAvascular Necrosis+2 more
University of California, Davis30 enrolled1 locationNCT06016634
Recruiting
Not Applicable

Contribution of the CEST Sequence in the Characterization of Radionecrosis of Brain Metastases of Pulmonary Origin

Brain MetastasesPulmonary CancerRadionecrosis
Assistance Publique - Hôpitaux de Paris60 enrolled1 locationNCT05977803
Recruiting
Not Applicable

Marrow Cellution™ vs. Traditional BMA Harvest Project

Hip ArthropathyAvascular Necrosis of BoneSubchondral Cysts
Ohio State University6 enrolled1 locationNCT06388993
Recruiting

Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty

Hip ReplacementFemur Head NecrosisPrimary, Secondary or Post-traumatic Osteoarthrosis+2 more
Corin2,500 enrolled13 locationsNCT02230826
Recruiting

Observational Study to Evaluate Long-Term Outcome in Hip Hemiarthroplasty

Hip FracturesOsteoarthritis, HipAvascular Necrosis of Hip+2 more
Corin368 enrolled4 locationsNCT05686278
Recruiting
Phase 4

Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG)

Hip FracturesFemoral Neck FracturesFemur Head Necrosis
Huazhong University of Science and Technology60 enrolled1 locationNCT06565910
Recruiting
Phase 2

Triple Antibiotic Paste vs Simvastatin for Lesion Sterilization and Tissue Repair in Primary Molars.

Pulpal necrosis
Dow University of Health Sciences60 enrolled1 locationNCT07264842
Recruiting

Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France

Apical periodontitisPulpitis - IrreversiblePulp Necrosis
University Hospital, Strasbourg, France100 enrolled1 locationNCT07297836
Recruiting
Not Applicable

Necrosectomy With Cryotechnology for Accelerated Removal

Acute PancreatitisPancreatic NecrosisAcute Pancreatic Necrosis+3 more
Christopher C. Thompson, MD, MSc20 enrolled1 locationNCT06553651
Recruiting
Phase 3

Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases

Radiation ToxicityBrain MetastasasesHigh Grade Glioma (III or IV)+4 more
The Netherlands Cancer Institute408 enrolled5 locationsNCT06888817
Recruiting

Perform Humeral System Study

Osteoarthritis ShoulderRotator Cuff Tear ArthropathyAvascular Necrosis+1 more
Stryker Trauma and Extremities300 enrolled10 locationsNCT05067543
Recruiting
Not Applicable

REMASTer: REcurrent Brain Metastases After SRS Trial

Brain MetastasesRadiation NecrosisRecurrent Tumor+1 more
Monteris Medical261 enrolled9 locationsNCT05124912