Phase 4 Neoplasm Clinical Trials

23 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 23 trials

Recruiting
Phase 4

Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

Breast Neoplasm Female
University of Wisconsin, Madison50 enrolled2 locationsNCT03096418
Recruiting
Phase 4

Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study

Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hepatocellular CarcinomaMetastatic Lung Non-Small Cell Carcinoma+18 more
OHSU Knight Cancer Institute160 enrolled1 locationNCT07405086
Recruiting
Phase 4

Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

OsteoradionecrosisMalignant Oral Cavity NeoplasmMalignant Skull Base Neoplasm
M.D. Anderson Cancer Center425 enrolled1 locationNCT04265430
Recruiting
Phase 4

Fluid Challenge and Plasma Volume, During Surgery

Colorectal, CancerGynecologic CancerUrologic Cancer+2 more
Joachim Zdolsek60 enrolled1 locationNCT05726136
Recruiting
Phase 4

Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing Surgery

Malignant Female Reproductive System Neoplasm
Mayo Clinic140 enrolled1 locationNCT06525740
Recruiting
Phase 4

Erector Spinae Block for Thoracic Surgery

Thoracic CancerPulmonary CancerThoracic Neoplasms+2 more
George Washington University70 enrolled1 locationNCT05521789
Recruiting
Phase 4

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Malignant Neoplasm in the Brain
City of Hope Medical Center10 enrolled1 locationNCT05376878
Recruiting
Phase 4

A Study of Revaree Plus in People With Breast Cancer

Breast CancerStage III Breast CancerHormone Receptor-Positive Breast Cancer+8 more
Memorial Sloan Kettering Cancer Center60 enrolled7 locationsNCT07042581
Recruiting
Phase 4

Tranexamic Acid During Colonic Endoscopic Resection Procedures

Colon Neoplasm
Assaf-Harofeh Medical Center200 enrolled1 locationNCT05345613
Recruiting
Phase 4

Prospective Multicenter Real-world Study of Surufatinib in Patients With Advanced Neuroendocrine Neoplasms

Neuroendocrine TumorsNeuroendocrine Neoplasms
Shanghai Zhongshan Hospital350 enrolled4 locationsNCT07272512
Recruiting
Phase 4

Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA)

Neuro Endocrine TumoursPDAC - Pancreatic Ductal AdenocarcinomaPancreas Adenocarcinoma+7 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)400 enrolled1 locationNCT07262957
Recruiting
Phase 4

Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

Metastatic Malignant Neoplasm in the LiverDigestive System Neuroendocrine Tumor G1Digestive System Neuroendocrine Tumor G2+3 more
Vanderbilt-Ingram Cancer Center6 enrolled1 locationNCT06016855
Recruiting
Phase 4

DPYD Pharmacogenomics and Fluoropyrimidine (FP) Dose-Adjustment

Breast NeoplasmsColorectal NeoplasmsHead and Neck Neoplasms+1 more
Rutgers, The State University of New Jersey100 enrolled12 locationsNCT07158164
Recruiting
Phase 4

Fenofibrate Role in the Prophylaxis From Peripheral Neuropathy Induced by Bortezomib, Lenalidomide and Dexamethasone (VRd) Protocol in the Treatment of Patients With Multiple Myeloma (MM)

Peripheral NeuropathyMultiple Myeloma, Neoplasms
Tanta University44 enrolled2 locationsNCT07025005
Recruiting
Phase 4

Primary Tumor Ablation and Outcome in Metastatic Renal Cell Carcinoma Treated With Immunotherapy Combinations.

Renal Cell CancerRadiotherapyKidney Cancer+3 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS409 enrolled1 locationNCT06903312
Recruiting
Phase 4

Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic Disease

Hematological Neoplasms
Wei Zhao1,500 enrolled2 locationsNCT03844360
Recruiting
Phase 4

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Breast CancerHeart FailureBreast Diseases+10 more
Silesian Centre for Heart Diseases600 enrolled4 locationsNCT05465031
Recruiting
Phase 4

Pre- Vs. Postoperative Thromboprophylaxis in Pancreatic Surgery

SurgeryPancreas CancerThrombosis+2 more
Helsinki University Central Hospital800 enrolled5 locationsNCT05245877
Recruiting
Phase 4

Impact of Using the Airseal System With Ultra-low Pneumoperitoneum in Patients Undergoing Robot-assisted Radical Prostatectomy: A Prospective, Comparative, Randomized Clinical Study.

Quality of Life (QOL)Prostate CarcinomaProstate Neoplasm+1 more
Brazilian Institute of Robotic Surgery200 enrolled2 locationsNCT06784986
Recruiting
Phase 4

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

NeoplasmsMetastatic Prostate CancerNeoplasms by Site+8 more
VA Greater Los Angeles Healthcare System15 enrolled1 locationNCT06706921