Phase 2 Nephropathy Clinical Trials
37 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 37 trials
Recruiting
Phase 2
Chinese Adults With Kidney Disease
Immunoglobulin A Nephropathy (IgAN)IC-MPGNComplement 3 Glomerulopathy (C3G)
ADARx Pharmaceuticals, Inc.30 enrolled10 locationsNCT07522099
Recruiting
Phase 2
Phase 2 Study of ADX-038 in Complement-Mediated Kidney Disease
IgA Nephropathy (IgAN)IgANC3G+2 more
ADARx Pharmaceuticals, Inc.45 enrolled29 locationsNCT06989359
Recruiting
Phase 2Phase 3
Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
Primary Membranous Nephropathy
Vertex Pharmaceuticals Incorporated176 enrolled98 locationsNCT07204275
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)
Lupus NephritisPrimary Membranous Nephropathy
Nkarta, Inc.120 enrolled19 locationsNCT06557265
Recruiting
Phase 2
Therapeutic Effect of Hydroxychloroquine on Immunoglobulin A (IgA) Nephropathy Course QUIgAN Study
IgA Nephropathy
Centre Hospitalier Universitaire de Saint Etienne334 enrolled7 locationsNCT06350630
Recruiting
Phase 2
A Study of the Safety and Activity of Sparsentan for the Treatment of Patients With Immunoglobulin A Nephropathy
Kidney DiseasesImmune System DiseasesAutoimmune Diseases+3 more
University of Leicester24 enrolled6 locationsNCT04663204
Recruiting
Phase 2
A Study to Evaluate the Long-Term Safety and Efficacy of HSK39297 Tablets in Primary IgA Nephropathy
IgA Nephropathy (IgAN)
Haisco Pharmaceutical Group Co., Ltd.73 enrolled2 locationsNCT07616700
Recruiting
Phase 2
A Study of JADE101 in Participants With Immunoglobulin A Nephropathy
IgA Nephropathy
Jade Biosciences, Inc.30 enrolled7 locationsNCT07541287
Recruiting
Phase 2
A Study to Assess the Effects of Zigakibart on IgA Nephropathy.
Immunoglobulin A Nephropathy (IgAN)
Novartis Pharmaceuticals32 enrolled9 locationsNCT07146906
Recruiting
Phase 2
Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of EVER001 in Participants With Selected Proteinuric Glomerular Diseases
Focal segmental glomerulosclerosis (FSGS)IgA Nephropathy (IgAN)Minimal Change Disease (MCD)
Everest Medicines (China) Co.,Ltd.45 enrolled2 locationsNCT07614477
Recruiting
Phase 2
Belimumab With Rituximab for Primary Membranous Nephropathy
Membranous NephropathyNephrotic Syndrome
National Institute of Allergy and Infectious Diseases (NIAID)58 enrolled20 locationsNCT03949855
Recruiting
Phase 2
A Study of SHR-2173 in Participants With Primary IgA Nephropathy
Primary IgA Nephropathy
Guangdong Hengrui Pharmaceutical Co., Ltd84 enrolled2 locationsNCT07354932
Recruiting
Phase 2
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases
Alport SyndromeFocal Segmental GlomerulosclerosisImmunoglobulin A Nephropathy+2 more
Travere Therapeutics, Inc.67 enrolled47 locationsNCT05003986
Recruiting
Phase 2
A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease
Primary Membranous Nephropathy
AstraZeneca43 enrolled21 locationsNCT07571746
Recruiting
Phase 2Phase 3
A Clinical Study of B007 in the Treatment of Primary Membranous Nephropathy.
Primary Membranous Nephropathy
Shanghai Jiaolian Drug Research and Development Co., Ltd216 enrolled21 locationsNCT06470191
Recruiting
Phase 2
A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy
Primary Membranous Nephropathy
Climb Bio, Inc.45 enrolled45 locationsNCT07096843
Recruiting
Phase 2
Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN
Glomerulonephritis, IGAImmunoglobulin A Nephropathy
Novartis Pharmaceuticals20 enrolled18 locationsNCT06797518
Recruiting
Phase 2
Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)
Primary Membranous Nephropathy
Alexion Pharmaceuticals, Inc.30 enrolled40 locationsNCT07157787
Recruiting
Phase 1Phase 2
A Study of MIL116 in Healthy Participants and Patients With IgA Nephropathy.
Immunoglobulin A Nephropathy
Beijing Mabworks Biotech Co., Ltd.130 enrolled1 locationNCT07375758
Recruiting
Phase 2
Study of WAL0921 in Patients With Glomerular Kidney Diseases
Diabetic NephropathiesPrimary Focal Segmental GlomerulosclerosisMinimal Change Disease+2 more
Walden Biosciences96 enrolled50 locationsNCT06466135